<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18543

Description Uncharacterized protein
SequenceMTAAPASPQQIRDRLLQAIDPQSNIRNMVAVLEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPAHQHEVALRGLAGATGSANGGAHNCRPEVGAAGPPRSIHDLKSRNDLQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKATHDPLVPNSSPLPTNGISGSPESFPGSLDGSGHAGPEGSRLERGENDKHSGKIPINAVRPHTSSPGLSKPPGPCLQAKASVLQQLDRVDETPGPPHPKGPPRCSFSPRNSRHEGSFARQQNLYAPKGSVPSPSPRPQALDATQVPSPLPLAQPSTPPVRRLELLSSSESPVRWLEQPESHQRLAGPGCKAGLSPAEPLLSRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHMEQPSRTELDKQEAKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLKQEESTRRGARQLHVLVPQSPPTDLPGLTREVTQDDLNRIQASQWPGVNGCQDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length600
PositionUnknown
OrganismCebus capucinus imitator
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Platyrrhini> Cebidae> Cebinae> Cebus.
Aromaticity0.04
Grand average of hydropathy-0.860
Instability index63.44
Isoelectric point9.51
Molecular weight65525.81
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18543
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     163.96|      39|      40|     119|     158|       1
---------------------------------------------------------------------------
  137-  180 (56.50/23.64)	PG..........QRLDRLGSRKRR....GDQRDlGH...pG..PPP.K.....VskatHDPLVPNS.SPL
  206-  238 (36.45/11.05)	.G..........SRLER...........GEN.D.KH...sGkiPIN.A.....V....RPHTSSPGLSKP
  239-  281 (34.35/10.00)	PGpclqakasvlQQLDRVD..ETP....GPP....H..pkG..PPRcS.....F....SPRNSRHE....
  325-  373 (36.66/11.15)	PV..........RRLELLSSSESPvrwlEQPE..SHqrlaG..PGC.KaglspA....EPLLSRAGFS..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.84|      17|      18|     415|     432|       2
---------------------------------------------------------------------------
  393-  411 (23.76/ 9.38)	KKKRYRPRDYTvnLDGQVA
  416-  432 (30.09/19.70)	KPVRLKERKLT..FDPMTR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18543 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HEVALRGLAGATGSANGGAHNCRPEVGAAGPPRSIHDLKSRNDLQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKATHDPLVPNSSPLPTNGISGSPESFPGSLDGSGHAGPEGSRLERGENDKHSGKIPINAVRPHTSSPGLSKPPGPCLQAKASVLQQLDRVDETPGPPHPKGPPRCSFSPRNSRHEGSFARQQNLYAPKGSVPSPSPRPQALDATQVPSPLPLAQPSTPPVRRLELLSSSESPVRWLEQPESHQRLAGPGCKAGLSPAEPLLSRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGV
2) PVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHMEQPSRTELDKQEAKASLQSPFEQTNW
3) RRGARQLHVLVPQSPPTDLPGLTREVTQDDLNR
90
417
522
415
477
554










Molecular Recognition Features






MoRF SequenceStartStop




1) IRDRLL
2) KKKKRYRPRDYTVNLD
3) RRLELL
11
392
327
16
407
332