<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18465

Description Mediator complex subunit 23
SequenceIVQMETQLQSIFEEVVVSSAAGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCIQWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQVLYYHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGRLFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKMEPVAVPPQAINSGSPAPQSNQVPVSLPVTQ
Length1349
PositionTail
OrganismCebus capucinus imitator
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Platyrrhini> Cebidae> Cebinae> Cebus.
Aromaticity0.10
Grand average of hydropathy0.023
Instability index44.77
Isoelectric point7.47
Molecular weight154281.86
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18465
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.05|      13|      17|    1040|    1055|       1
---------------------------------------------------------------------------
 1040- 1053 (24.51/19.43)	RPQG.WCLSDTYLkC
 1058- 1071 (23.54/ 7.53)	REENpWVPDDTYY.C
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.37|      18|      21|     241|     260|       2
---------------------------------------------------------------------------
  241-  260 (29.66/21.88)	LDP..ATLRFPLKGllPYDKDL
  261-  280 (29.71/15.81)	FEPqtALLRYVLEQ..PYSRDM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.34|      17|      21|     896|     913|       3
---------------------------------------------------------------------------
  896-  913 (26.47/23.90)	NDFRNRVSDFVKENsPEH
  917-  933 (34.87/26.26)	NDWHTKHMNYHKKY.PEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.00|      15|      20|     981|    1000|       4
---------------------------------------------------------------------------
  981- 1000 (18.08/24.26)	PVSKSLETLldHlggLYKFH
 1003- 1017 (30.92/18.62)	PVTYLYNTL..H...YYEMH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     281.18|      78|     232|     561|     646|       5
---------------------------------------------------------------------------
  496-  558 (81.19/38.63)	...ALVETiYG.............NGIMR...........IPLPGT...NCMASGSI.TP......LPM..NLLDSLTVHAKMSLIHSIATRViklAHAKSS
  561-  639 (129.03/84.58)	LAPALVET.YSRLLVYMEIESLGIKGFIS...........QLLPTV..FKSHAWGILHTL......LEMFsYRMHHIQPHYRVQLLSHLHTLA...AVAQTN
  677-  758 (70.96/34.82)	VLSAESEE.LNRALILTLARATHVTDFFTgsdsiqgtwckDILQTImsFTPHNWAS.HTLscfpgpLQAF.FKQNNVPQESRFNL.................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.77|      23|      74|     776|     810|       8
---------------------------------------------------------------------------
   61-   87 (37.87/12.64)	IVKFIHGQHSPKrisfLYDCL..AMAVET
  778-  802 (38.90/32.55)	IITHFSMQGSPP....LFLCLlwKMLLET
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.82|      12|      21|     353|     364|      10
---------------------------------------------------------------------------
  353-  364 (21.06/13.29)	HMVLSLHQKLAG
  373-  384 (22.76/15.04)	HLMWVLLQFISG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.63|      16|      21|     934|     949|      11
---------------------------------------------------------------------------
  934-  949 (27.99/15.33)	LYFEGLAEQVDPPVQI
  956-  971 (29.64/16.64)	IYFGNVCLRFLPVFDI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18465 with Med23 domain of Kingdom Metazoa
Unable to open file!