<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18421

Description Uncharacterized protein
SequenceMTAAPASPQQIRDRLLQAIDPQSNIRNMVAVLEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPAHQHEAALRGLAGATGSANGGAHNCRPEVGAAGPPRSIHDLKSRNDLQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDPLVPNSSPLPTNGISGSPESFPGSLDGSGHAGPEGGRLERGENDKHSGKIPINAVRPHTSSPGLGKPPGPCLQPKASVLQQLDRVDETPGPHHPKGPPRCSFSPRNSRHEGSFARQQSLYAPKGSVPSPSPRPQALDATQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPESHQRLAGPGCKAGLSPAEPLLSRAGFSPDSSKADSDAASSGGSDGKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHMEQQSRTELDKQEAKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLKQEESTRQGARQLHVLVPQSPPTDLPGLTRDITQDDLDRIQASQWPGVNGCQDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length600
PositionUnknown
OrganismCercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Cercopithecidae> Cercopithecinae> Cercocebus.
Aromaticity0.04
Grand average of hydropathy-0.864
Instability index63.07
Isoelectric point9.41
Molecular weight65430.67
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18421
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.80|      13|      15|     275|     288|       1
---------------------------------------------------------------------------
  275-  288 (19.91/14.02)	PRNSRHEGSfARQQ
  293-  305 (25.89/13.38)	PKGSVPSPS.PRPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      72.19|      19|      20|     415|     433|       2
---------------------------------------------------------------------------
  393-  415 (19.19/ 8.34)	KKKRYRPRDYTvnLDgqV..AEAGV
  416-  434 (32.53/19.13)	KPVRLKERKLT..FD..P..MTRQI
  435-  454 (20.47/ 9.38)	KPLTQKEPVRA..DS..PvhMEQQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     152.80|      28|     111|     139|     166|       3
---------------------------------------------------------------------------
  139-  166 (52.71/22.07)	QRLDRLGS.RKRRG...........DQRDLGHP.GP..PPKVS
  183-  205 (27.18/ 7.77)	NGIS..GSpESFPG...........SLDGSGHA.GP..E....
  207-  248 (31.48/10.18)	GRLERGEN.DKHSGkipinavrphtSSPGLGKPpGPclQPKAS
  251-  272 (41.43/15.75)	QQLDRVD...ETPG...........PH....HP.KG..PPRCS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.73|      31|     209|     321|     357|       4
---------------------------------------------------------------------------
   72-  112 (42.02/17.46)	RAKKLLRSWQKLIEPAHQHEAALRgLAGATgsanggahnCR
  327-  357 (56.71/41.65)	RRLELLPSAESPVRWLEQPESHQR.LAGPG.........CK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.01|      13|      22|     489|     503|       7
---------------------------------------------------------------------------
  489-  503 (17.33/13.29)	YLSRQSSllSSSGAQ
  514-  526 (22.68/11.35)	YLKQEES..TRQGAR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18421 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HQHEAALRGLAGATGSANGGAHNCRPEVGAAGPPRSIHDLKSRNDLQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDPLVPNSSPLPTNGISGSPESFPGSLDGSGHAGPEGGRLERGENDKHSGKIPINAVRPHTSSPGLGKPPGPCLQPKASVLQQLDRVDETPGPHHPKGPPRCSFSPRNSRHEGSFARQQSLYAPKGSVPSPSPRPQALDATQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPESHQRLAGPGCKAGLSPAEPLLSRAGFSPDSSKADSDAASSGGSDGKKKKRYRPRDYTVNLDGQVAEAGV
2) PVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHMEQQSRTELDKQEAKASLQSPFEQTNW
3) RQGARQLHVLVPQSPPTDLPGLTRDITQDDLDR
88
417
522
415
477
554










Molecular Recognition Features






MoRF SequenceStartStop




1) IRDRLL
2) KKKKRYRPRDYTVNLD
3) VRRLELL
11
392
326
16
407
332