<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18398

Description Runt related transcription factor 2
SequenceMRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRNPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISARSRYSLR
Length285
PositionKinase
OrganismCercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Cercopithecidae> Cercopithecinae> Cercocebus.
Aromaticity0.05
Grand average of hydropathy-0.657
Instability index72.27
Isoelectric point10.25
Molecular weight31303.65
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
DNA binding	GO:0003677	IEA:InterPro
DNA-binding transcription factor activity	GO:0003700	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18398
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.01|      10|      22|      35|      44|       1
---------------------------------------------------------------------------
   35-   44 (21.13/ 8.08)	QQQQQQQQQQ
   58-   67 (20.88/ 7.93)	QQQQQQQQQE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     163.95|      51|     133|      86|     144|       2
---------------------------------------------------------------------------
   86-  144 (80.56/67.11)	PRL.RPPHDNRTMVEIIAD..HPAELVRTDSPNfLCSVLP.SHWRcNKTLPvafkvvALGEVP
  219-  273 (83.39/48.56)	PREpRNPRQAQSSPPWSYDqsYPSYLSQMTSPS.IHSTTPlSSTR.GTGLP......AITDVP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18398 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAA
2) SQMTSPSIHSTTPLSSTRGTGLPAITDVPR
1
245
76
274










Molecular Recognition Features






MoRF SequenceStartStop




1) MSDVSPVVAA
2) VDPSTSRRFSPPSSSLQP
25
5
34
22