<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18206

Description Transducin beta like 1 X-linked
SequenceMTELTGASSRCCPRPARRGAMQSPVDHVQRLRGREGGSHSASTSSQRGEAKMSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAASAATSTTAGVSQQNPPKNAQTPVNGEEIRAFNITEHNDGKEGNRDPEQAVESFLSPVFLFCRSGDSTARIWNLNENSNGCSTQLVLRHCIREGGHDVPSNKDVTSLDWNTDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCERPVKTFQGHTNEVNAIKWDPSGILLASCSDDMTLKIWSMKQEVCVHDLQAHSKEIYTIKWSPSGPATSNPNSKIMLASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQNGNLVYSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK
Length552
PositionTail
OrganismAotus nancymaae (Ma's night monkey)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Platyrrhini> Aotidae> Aotus.
Aromaticity0.08
Grand average of hydropathy-0.391
Instability index42.31
Isoelectric point6.02
Molecular weight60302.60
Publications

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-KW
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP18206
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     357.53|      40|      40|     360|     399|       1
---------------------------------------------------------------------------
  245-  282 (41.36/19.30)	TQLVLR...HCiREG.GHD..VPS....NKDVTSLDWNTDG.........tlL.A.TGS
  283-  323 (41.37/19.30)	YD.GF.....A.RIWTEDGnlASTLGQHKGPIFALKWNRKG..........nY.IlSAG
  324-  364 (51.57/25.61)	VDKTTI...IW.DAHTGEA..KQQFPFHSAPALDVDWQNN..........ttF.A.SCS
  365-  406 (66.08/34.58)	TDMCIH...VC.RLGCERP..VKTFQGHTNEVNAIKWDPSG.........ilL.A.SCS
  407-  457 (55.99/28.34)	DDMTLK...IW.SMKQEVC..VHDLQAHSKEIYTIKWSPSGpatsnpnskimL.A.SAS
  458-  499 (43.38/20.55)	FDSTVRlwdVE.RGVC.....IHTLTKHQEPVYSVAFSPDG..........kYlA.SGS
  500-  541 (57.76/29.44)	FDKCVH...IW.NTQNGNL..VYSYRG.TGGIFEVCWNARG........dkvG.A.SAS
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP18206 with Med16 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) LTGASSRCCPRPARRGAMQSPVDHVQRLRGREGGSHSASTSSQRGEA
2) SAATSTTAGVSQQNPPKNAQTPVNGEEIRAFNITEHNDGKEGNRDPEQ
4
164
50
211

Molecular Recognition Features

MoRF SequenceStartStop
1) PRPARRG
13
19