<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18181

Description Uncharacterized protein
SequenceATAPCPGIFFINILRILARFFSPKCKYLLLLFQNAFSVFQDESSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKSTTETGGGDEGQKARKNKQETFPTLETVFTKLQLLSYFDQHQVTSQISNNVLEQITSFASGTSYHLPLAHHIQLIFDLMEPALNINGLIDFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFGDLFSSACSKVKQTIYNNVMPANSNLRWDPDFMMDFIENPSARSINYSMLGKILSDNAANRYSFVCNTLMNVCMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSNHVWGFNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACGDADAEPGARMTCRLLLHLFRAPQACILPQATGKPFPGIRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGNNSVSSLKNDDFTMRGLRCDGNADDIWTASQNPKSCGKSISIETANLREYARYVLRTICQQEWVGEHCLKEPERLCTDKELILDPVLSNMQAQKLLQLICYPHGIKECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPGSGSVAEMNNLLDNIAKATIEVFQQSAELNNNSSNSGMSLFNPNSIGSADTSSTRQNGIKTFLSSSERRGVWLVAPLIARLPTSVQGRVLKAAGEELEKGQHLGSSSKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWREERYQDDIKARQMMHEALQLRLNLVGGMFDTVQKSTQWTTDWALLLLQIITSGTVDMHTNNELFTTVLDMLGVLINGTLASDLSNASPGGSEENKRAYMNLVKKLKKELGDKRSESIDKVQQLLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQGLQVSTKQKMSPWDLFEGQKNPAPLSWAWFGTVRVDRRVIKYEEQHHLLLYHTHPKPKPRSYYLEPLPLPPEEEEEEPTSPVSQEPERKSAELSDHGKTTTDEEKKTKGRKRKTKSSSRVDEYPQSNIYRVPPNYSPISSQMMHHPQSTLWGYNLVGQPQQPGFFLQNQSLNPGGSRLDPAGSFVPTNTKQALSNMLQRRSGAMMQPPSLHTITSQQQLIQMKLLQQQQQQRLLRQAQTRPFQQGQPGDQAPLFAAQTRPSPQLPQYPGLQQAQTMPQGYTMYGTQMPLQQTSQQQASSVVLSPSYNTRAYPAAHSNPVLMERLRQIQQQPSGYIQQQPSPYLQPLTGSQRLNHQALQQSPLVGGGIDAVLTSAHPNLPSVPLPQDPMRPRQPQVRQQQRILQMQQPQQPQPQQPPQPQQSSQPQSQTLGLQAMQSQQPLFPRQGLQQTQQQQQTAALVRQLQKQLSSNQPQQGVTPYGHPSHF
Length1471
PositionKinase
OrganismAotus nancymaae (Ma's night monkey)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Platyrrhini> Aotidae> Aotus.
Aromaticity0.06
Grand average of hydropathy-0.445
Instability index62.62
Isoelectric point8.53
Molecular weight164490.64
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
beta-catenin binding	GO:0008013	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18181
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     110.89|      17|      17|    1212|    1228|       1
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 1212- 1228 (32.38/10.64)	LQQQQQQRLLRQAQTRP
 1248- 1264 (27.60/ 8.05)	SPQLPQYPGLQQAQTMP
 1312- 1328 (26.65/ 7.53)	RQIQQQPSGYIQQQPSP
 1380- 1396 (24.27/ 6.24)	PQVRQQQRILQMQQPQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     112.96|      26|      26|    1400|    1425|       2
---------------------------------------------------------------------------
 1275- 1305 (22.45/ 6.30)	.....PLQQTSQQQassvvlspsyNTRAYPAAHSNP
 1400- 1425 (48.27/22.78)	QQPPQPQQSSQPQS..........QTLGLQAMQSQQ
 1427- 1451 (42.24/18.93)	LFPRQGLQQTQQQQ..........QTAAL.VRQLQK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.04|      13|      20|     689|     707|       3
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  672-  687 (16.56/11.40)	AEMNNlldNIAKATIE
  693-  705 (22.47/12.36)	AELNN...NSSNSGMS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.94|      13|      30|     585|     597|       4
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  585-  597 (23.79/13.67)	CLKEPERLCTDKE
  617-  629 (26.15/15.76)	CYPHGIKECTEGD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.27|      20|      27|     436|     461|       5
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  440-  461 (34.89/28.11)	ACGDADAE....PGARMTCRllLHLF
  466-  489 (33.38/12.94)	ACILPQATgkpfPGIRSSCD..RHLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.34|      37|      42|     729|     766|       6
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  729-  766 (57.85/37.30)	LSSS...ER.RGVWLVAPLIARLP.TSVQGRVLKAAGEELEkG
  769-  810 (49.49/27.22)	LGSSskkERdRQKQKSMSLLSQQPfLSLVLTCLKGQDEQRE.G
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     263.44|      81|     180|      91|     211|       7
---------------------------------------------------------------------------
  130-  211 (128.38/144.47)	ISNNVLEQITSFASGTSYHLPLAHHIQLIFDlMEPALNINGLIDFAIQLLNELSVVEAELL..LKSSSLAGSYTTGL..CVCIVAV
  316-  400 (135.06/77.37)	INYSMLGKILSDNAANRYSFVCNTLMNVCMG.HQDAGRINDIANFSSELTACCTVLSSEWLgvLKALCCSSNHVWGFndVLCTVDV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.87|      16|     189|     228|     244|      10
---------------------------------------------------------------------------
  228-  244 (26.86/25.26)	QVFeGLCGVVKHVVNPS
  420-  435 (30.01/22.30)	QCF.SLEDVVQHVALPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.25|      13|      19|    1104|    1122|      13
---------------------------------------------------------------------------
 1104- 1116 (24.16/21.58)	SSRVDEYPQSNIY
 1126- 1138 (27.09/ 8.66)	SSQMMHHPQSTLW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.80|      23|      23|     835|     857|      15
---------------------------------------------------------------------------
  835-  857 (39.80/32.62)	I.KARQMMHE.ALQLRLNLVGGMFD
  859-  883 (29.00/21.19)	VqKSTQWTTDwALLLLQIITSGTVD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.76|      12|      29|      57|      68|      16
---------------------------------------------------------------------------
   57-   68 (21.82/13.03)	GVGKERDEARHQ
   89-  100 (21.94/13.14)	GGGDEGQKARKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.70|      11|      28|    1339|    1349|      17
---------------------------------------------------------------------------
 1339- 1349 (19.42/ 9.36)	LNHQALQQSPL
 1360- 1370 (20.28/10.12)	SAHPNLPSVPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.83|      22|      28|    1043|    1064|      20
---------------------------------------------------------------------------
 1043- 1064 (39.26/28.66)	KPKPRSYYLEPLPLPPEEEEEE
 1072- 1093 (35.57/25.11)	EPERKSAELSDHGKTTTDEEKK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18181 with Med12 domain of Kingdom Metazoa
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