<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18166

Description Mediator complex subunit 23
SequenceMETQLQSIFEEVVVSSAAGHPGLCMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCIQWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQVLYYHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGRLVDNILSAFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKMEPVAVPPQAINSGSPAPQSNQVPVSLPVTQ
Length1358
PositionTail
OrganismAotus nancymaae (Ma's night monkey)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Platyrrhini> Aotidae> Aotus.
Aromaticity0.10
Grand average of hydropathy0.024
Instability index45.17
Isoelectric point7.31
Molecular weight155161.84
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18166
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.11|      13|      17|    1042|    1057|       1
---------------------------------------------------------------------------
 1042- 1055 (24.76/21.97)	RPQG.WCLSDTYLkC
 1060- 1073 (24.35/ 9.17)	REENpWVPDDTYY.C
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.37|      18|      21|     243|     262|       2
---------------------------------------------------------------------------
  243-  262 (29.66/20.54)	LDP..ATLRFPLKGllPYDKDL
  263-  282 (29.71/14.81)	FEPqtALLRYVLEQ..PYSRDM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.34|      17|      21|     898|     915|       3
---------------------------------------------------------------------------
  898-  915 (26.47/20.88)	NDFRNRVSDFVKENsPEH
  919-  935 (34.87/22.94)	NDWHTKHMNYHKKY.PEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.22|      15|      15|     999|    1013|       5
---------------------------------------------------------------------------
  999- 1013 (28.53/20.22)	YKFHDRPVTYLYNTL
 1016- 1030 (24.69/16.40)	YEMHLRDRAFLKRKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     192.54|      59|     738|      21|      89|       6
---------------------------------------------------------------------------
   21-   89 (98.96/75.45)	PG.LCMFM...DTPEDEKTKLISCLGAFRQFWGGLSQESHeqciqwIVKFIHGQHSPKrisfLYDCL..AMAVET
  740-  804 (93.58/51.41)	PGpLQAFFkqnNVPQESRFNLKKNVEEEYRKWKSMSNEND......IITHFSMQGSPP....LFLCLlwKMLLET
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.35|      29|     738|     190|     230|       8
---------------------------------------------------------------------------
  190-  224 (47.77/34.85)	LYPEGklphwlLGNLVSDFVDTFRPTARI..NSICGR
  936-  966 (48.58/17.29)	LYFEG......LAEQVDPPVQIQSPYLPIyfGNVCLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      31|     343|     352|       9
---------------------------------------------------------------------------
  343-  352 (18.69/10.07)	IFFVLFQFAS
  376-  385 (19.45/10.79)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     157.83|      53|      80|     437|     489|      10
---------------------------------------------------------------------------
  437-  489 (91.36/56.50)	NRKAQNDNSKLQIPIP..................HSLRLHHEF.LQQSLRNKSLQMNDYK..IALLCNAYSTNS
  499-  572 (66.47/39.15)	LVETIYGNGIMRIPLPgtncmasgsitplpmnllDSLTVHAKMsLIHSIATRVIKLAHAKssVALAPALVETYS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      58.84|      12|     827|     396|     407|      14
---------------------------------------------------------------------------
  396-  407 (24.41/13.54)	FLPVMKL.FDLLY
  967-  975 (17.12/ 7.36)	FLPV....FDIVI
 1225- 1237 (17.30/ 7.52)	LLPIVKTeFQLLY
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18166 with Med23 domain of Kingdom Metazoa
Unable to open file!