<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18147

Description Transcription elongation factor A2
SequenceMGKEEEIARIARRLDKMVTKKSAEGAMDLLRELKAMPVTLHLLQSTRVGMSVNALRKQSSDEEVIALAKSLIKSWKKLLDASDAKARERGRGTPLPTPSRDASEAQDPSRKRPELPRAPSTPRITTFPPVPVTCDAVRSKCREMLTAALQTDHDHVATGADCKRLSAQIEEYILSLARIFRDVGNTDMKYKNRVRSRISNLKDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDELKEVRKAMTKEAIREHQMARTGGTQTDLFTCGKCRKNNCTYTQVQTRSSDEPMTTFVVCNECGNRWKVGERPRLPSQPRSLVVGCVSLCGGVNWGWPCPASLLGVSGTVGRDPSLGCTCAASHSGALVWPQDWRPHPFLTVLLSPRADMLHAAPSPVSSVTQLLWRPQKAACPALHLPAWIAPFCPFPLVIKCFLLPFCSPQLLLLVGPRAPHMTHSHCCGQGPSLGLGPGGSVPGEGLG
Length475
PositionUnknown
OrganismAotus nancymaae (Ma's night monkey)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Platyrrhini> Aotidae> Aotus.
Aromaticity0.04
Grand average of hydropathy-0.301
Instability index53.86
Isoelectric point9.34
Molecular weight51898.64
Publications

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
nucleic acid binding	GO:0003676	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP18147
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     123.16|      30|      55|     332|     361|       1
---------------------------------------------------------------------------
  332-  355 (40.31/21.73)	........................PCPASLLGVSG..........TVGRDPSLGCTCA
  356-  387 (33.62/16.83)	ASHSGA..........lvwpqdwrPHP..FL..............TVLLSPRADMLHA
  389-  408 (27.53/12.35)	........................PSPVS..SVTQ..........LLWR.PQ.KAACP
  409-  462 (21.69/ 8.06)	ALHLPAwiapfcpfplvikcfllpFCSPQLLLLVGpraphmthshCCGQGPSLG....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.63|      22|      25|     280|     301|       2
---------------------------------------------------------------------------
  280-  301 (43.14/24.60)	QTRSSDEPMTTFVVC.NECGN.RW
  306-  329 (34.49/18.23)	RPRLPSQPRSLVVGCvSLCGGvNW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     151.45|      49|      52|      80|     130|       3
---------------------------------------------------------------------------
   80-  117 (56.25/30.34)	.................DASDAKARERGRGTPLPTPSRDASEAQDPSRKRPELPR
  118-  171 (71.29/46.57)	APSTPRIttFPPVpvtcDAVRSKCREM.LTAALQTDHDHVATGADCKRLSAQIEE
  173-  195 (23.91/ 9.04)	ILSLARI..FRDV....GNTDMKYKNRVR..........................
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP18147 with Med26 domain of Kingdom Metazoa

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