<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18146

Description Transcription elongation factor A2
SequenceAMGKEEEIARIARRLDKMVTKKSAEGAMDLLRELKAMPVTLHLLQSTRVGMSVNALRKQSSDEEVIALAKSLIKSWKKLLDASDAKARERGRGTPLPTPSRDASEAQDPSRKRPELPRAPSTPRITTFPPVPVTCDAVRSKCREMLTAALQTDHDHVATGADCKRLSAQIEECIFRDVGNTDMKYKNRVRSRISNLKDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDELKEVRKAMTKEAIREHQMARTGGTQTDLFTCGKCRKNNCTYTQVQTRSSDEPMTTFVVCNECGNRWKFC
Length299
PositionUnknown
OrganismAotus nancymaae (Ma's night monkey)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Platyrrhini> Aotidae> Aotus.
Aromaticity0.03
Grand average of hydropathy-0.650
Instability index54.77
Isoelectric point9.39
Molecular weight33469.16
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
nucleic acid binding	GO:0003676	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18146
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.82|      16|      19|      81|      99|       1
---------------------------------------------------------------------------
   81-   97 (25.87/11.94)	DASDAKARERGRGtPLP
  102-  117 (28.95/12.87)	DASEAQDPSRKRP.ELP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     195.25|      48|      48|     183|     230|       2
---------------------------------------------------------------------------
  138-  184 (58.41/33.67)	....VRSKCREMLTAALQTDHDHVA.TGADCKRlsaQIEECIFRDVGNTDMK
  185-  232 (73.49/44.07)	YKNRVRSRISNLKDAKNPDLRRNVL.CGAITPQ...QIAVMTSEEMASDELK
  235-  281 (63.34/37.07)	RKAMTKEAIREHQMARTGGTQTDLFtCGKCRKN...NCTYTQVQTRSSDE..
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18146 with Med26 domain of Kingdom Metazoa
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