<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18139

Description Uncharacterized protein
SequenceMTAAPASPQQIRDRLLQAIDPQSNIRNMVAVLEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPAHQHEVALRGLAGATGSANGGAHNCRPEVGAAGPPRSIHDLKSRNDLQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKATHDPLVANSSPLPTNGISGSPESFPSSLDGSGHAGPEGSRLERGENDKHSGKIPINAVRPHTSSPGLSKPPGPCLQAKASVLQQLDRVDETPGPPHPKGPPRCSFSPRNSRHEGSFTRQQNLYVPKGSMPSPSPRPQALDATQVPSPLPLAQPSTPPVRRLELLPSSESPVRWLEQPESHQRLAGPGCKAGLSPAEPLLSRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRVDSPVHMEQPSRTELDKQEAKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLKQEESTRRGARQLHVLVPQSPPTDLPGLTREVTQDDLNRIQASQWPGVNGCQDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length600
PositionUnknown
OrganismAotus nancymaae (Ma's night monkey)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Platyrrhini> Aotidae> Aotus.
Aromaticity0.04
Grand average of hydropathy-0.857
Instability index63.99
Isoelectric point9.51
Molecular weight65658.04
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats
>MDP18139
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     160.98|      38|      38|     228|     265|       1
---------------------------------------------------------------------------
  132-  172 (51.15/19.01)	DLQRLPGQRLDRLGSRKRRGDQRDLGhPGP.P.PkvsKATH.DP
  197-  233 (46.54/16.67)	DGSGHAGP....EGSRLERGEN.DKH.SGKiPINavrPHTS.SP
  234-  275 (63.29/25.17)	GLSKPPGPCLQAKASVLQQLDRVDET.PGP.PHPkgpPRCSfSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      96.32|      22|      22|     300|     321|       2
---------------------------------------------------------------------------
  300-  321 (40.08/21.63)	PSPRPQALDATQVPSPLP.LAQP
  324-  345 (33.95/17.10)	PPVRRLELLPSSE.SPVRwLEQP
  442-  454 (22.29/ 8.47)	.PVR........VDSPVH.MEQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.38|      16|      18|      87|     102|       3
---------------------------------------------------------------------------
   87-  102 (27.51/15.17)	AHQHEVALRGLAGATG
  104-  119 (29.87/17.04)	ANGGAHNCRPEVGAAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.97|      18|      20|     403|     422|       4
---------------------------------------------------------------------------
  417-  435 (24.32/14.11)	PVRLKE.............rKLTFDPMTRQ..IK
  436-  469 (13.66/11.74)	PLTQKEpvrvdspvhmeqpsRTELDKQEAKasLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.76|      34|      62|     470|     506|       6
---------------------------------------------------------------------------
  470-  506 (50.90/38.24)	SPfeQTNWKELSRnEIIQSYLSR.QSSLLSS.SGAQ.TPG
  535-  571 (50.86/28.00)	SP..PTDLPGLTR.EVTQDDLNRiQASQWPGvNGCQdTQG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18139 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EVALRGLAGATGSANGGAHNCRPEVGAAGPPRSIHDLKSRNDLQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKATHDPLVANSSPLPTNGISGSPESFPSSLDGSGHAGPEGSRLERGENDKHSGKIPINAVRPHTSSPGLSKPPGPCLQAKASVLQQLDRVDETPGPPHPKGPPRCSFSPRNSRHEGSFTRQQNLYVPKGSMPSPSPRPQALDATQVPSPLPLAQPSTPPVRRLELLPSSESPVRWLEQPESHQRLAGPGCKAGLSPAEPLLSRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGV
2) PVRLKERKLTFDPMTRQIKPLTQKEPVRVDSPVHMEQPSRTELDKQEAKASLQSPFEQ
3) RRGARQLHVLVPQSPPTDLPGLTREVTQDDLNR
91
417
522
415
474
554










Molecular Recognition Features






MoRF SequenceStartStop




1) IRDRLL
2) KKKKRYRPRDYTVNLD
3) RRLELL
11
392
327
16
407
332