<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18136
Description |
Mediator of RNA polymerase II transcription subunit 9 |
Sequence | MASAGVAAGRQAEDALPPTSDQPLPDNKPLPPPQPPPPVAAPQPQQSPAPRPQSPARAREEENYSFLPLVHNIIKCMDKDSPEVHQDLNALKTKFQEMRKLISTMPGIHLSPEQQQQQLHSLREQVRTKNELLQKYKSLCMFEIPKE |
Length | 147 |
Position | Middle |
Organism | Aotus nancymaae (Ma's night monkey) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia>
Eutheria> Euarchontoglires> Primates> Haplorrhini> Platyrrhini> Aotidae>
Aotus.
|
Aromaticity | 0.03 |
Grand average of hydropathy | -0.861 |
Instability index | 95.03 |
Isoelectric point | 6.91 |
Molecular weight | 16481.66 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364145
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP18136
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 61.57| 14| 16| 23| 36| 1
---------------------------------------------------------------------------
23- 36 (31.35/10.90) PLPDNKPLPPPQPP
42- 55 (30.23/10.28) PQPQQSPAPRPQSP
---------------------------------------------------------------------------
|