<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18121

Description Sulfatase (Fragment)
SequenceVSLTHPHDPYTITNKYWNLYEGVDVALPKVRLPKEKLDAHSQRLLRVCDLWDHDLTDDQIKRAKRAYYGSVSYVDDCIGRLLGTLDEAGLADNTIIIFSGDHGDMLGERGLWYKMSYFESSVRVPLLVHYPKWFEPHRVPSNVSTLDLLPTICDLTGIKLAPCLPMDGVSMMPHLLGKEGPDTVFAEYTGEGTIRPTMMIRRGPWKYVTCPADEPQFYNLARDPRELDNLARLLRVAPQTPEEEEAKAAFEQYDAEAKAKWDFDAITAQVLQSQRSRRLVWGALTEGAFTSWDFDPVDDGRTKYIRSNMPLDHLERRARYPMVDTHGYEVTKTHHQHNHRRIVIEPSTLSRRYPCCHCPHPRRRGEHRPGRVKRGTMATLGLDDDELKSVEQTLSRLAQLSSSIQSLKLDILKSNPLPHPSSLQASAQILQRNLQTVLDNLSENAELFARIAIHPSTNYPGRAQESILTQLLRKKLEPDVEELVAEGRETARLATPEGLAELQGIWDELREWTHGRIAAYVRDEAGSVYTKEEREMGADKVRTGLRRGLDEESDDEDEAEDGDEDDGDDEDDEDDDEGGKGRTQPPRGPEPETLLWFAARGDFEVPRNVEYGRKGAARKGLEGVNIPPERMEGARSA
Length637
PositionHead
OrganismTolypocladium capitatum
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Ophiocordycipitaceae> Tolypocladium.
Aromaticity0.07
Grand average of hydropathy-0.713
Instability index45.01
Isoelectric point5.24
Molecular weight72214.06
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
sulfuric ester hydrolase activity	GO:0008484	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18121
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.30|      11|     104|     341|     354|       1
---------------------------------------------------------------------------
  341-  354 (17.60/19.19)	RIVIEPSTlsrRYP
  450-  460 (23.70/15.20)	RIAIHPST...NYP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.83|      10|      28|     257|     266|       2
---------------------------------------------------------------------------
  257-  266 (19.56/12.79)	AKAKWDFDAI
  288-  297 (21.27/14.57)	AFTSWDFDPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.38|      33|      39|     519|     552|       4
---------------------------------------------------------------------------
  519-  552 (52.03/33.58)	AYVRDE.AGSVYTKEEREMGAdKVRTGLRRGLDEE
  559-  592 (57.35/32.80)	AEDGDEdDGDDEDDEDDDEGG.KGRTQPPRGPEPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.61|      20|      22|     387|     408|       5
---------------------------------------------------------------------------
  387-  408 (26.13/20.49)	LKSveQTLSRLAQLSSSIQSLK
  412-  431 (33.49/20.10)	LKS..NPLPHPSSLQASAQILQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.33|      28|     188|      17|      47|       6
---------------------------------------------------------------------------
   17-   47 (38.66/37.89)	WNlYEGVDVALPKV....RLPKEkLDaHSQRLLRV
  205-  236 (48.67/31.58)	WK.YVTCPADEPQFynlaRDPRE.LD.NLARLLRV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18121 with Med8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DEAGSVYTKEEREMGADKVRTGLRRGLDEESDDEDEAEDGDEDDGDDEDDEDDDEGGKGRTQPPRGPEPETLLWFAARG
2) PCCHCPHPRRRGEHRPGRVKRGTMATLGLDDD
3) RNVEYGRKGAARKGLEGVNIPPERMEGARSA
523
354
607
601
385
637










Molecular Recognition Features






MoRF SequenceStartStop




1) GKGRTQPPRGPEPETLLWFAARGDFEVPRNVEYGRKG
579
615