<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18106
Description |
Mediator of RNA polymerase II transcription subunit 11 |
Sequence | MSAPHDVVMGEGDAPENPPVQQPFTVEENIHQLNATDKSIVQLMNHAATALNALTTPATSSIANPSPDAAARKPALDPPAQMEAFRRATDSFLTTLHSVDVRMKRQVLALEEAGIVNLSNAPRQGTNGAVKASLQPNGVGTVGGLDVGWLNSRSTGVERGMEAELWQEALKFLEKQGEKVKLAERP |
Length | 186 |
Position | Head |
Organism | Tolypocladium capitatum |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Hypocreomycetidae> Hypocreales> Ophiocordycipitaceae> Tolypocladium.
|
Aromaticity | 0.03 |
Grand average of hydropathy | -0.377 |
Instability index | 44.23 |
Isoelectric point | 5.38 |
Molecular weight | 19852.15 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364147
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP18106
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 50.00| 15| 15| 135| 149| 1
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135- 149 (27.79/18.56) QPNGVGTVGGLDVG.W
151- 166 (22.21/13.56) NSRSTGVERGMEAElW
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 69.93| 20| 20| 39| 58| 2
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39- 58 (33.81/18.49) SIVQLMNHAATALNALTTPA
61- 80 (36.12/20.16) SIANPSPDAAARKPALDPPA
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