<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18099

Description Mediator of RNA polymerase II transcription subunit 31-like protein (Fragment)
SequenceMASGTRPRNVQPTVASASVGVANVAKNGRGMKTDPAWKHGVLINEATTRVICNYCQRDFTGGAHRLKHHLAGTSRDIKCCKYVPDDVKENMEDVIFMKGLRKKMRKKKCIDIEGHVDEVEVAPNSNGKSQSVGEIALKDTFKRGLTTLTVIVEDSDSMASKAESESPTDTPPSPPNKTRVYHRRGAKGKSEQGGGSAISTQPKEIRGGITEGTNGDGKVLEIVPKNVYKDPDDGRQRFLLELEFVQCLANPTYIHYLAQNRYFEDEAFIGYLKYLQYWQRPEYIKFIMYPHCLYFLELLQNANFRNAMAHPTNKELAHRQQFYFWKNYRNNRLKHILPKPLPEPTAALPASTQPQPPVPALPPPPPATNVAATTSSTQAPSPMPYGSVAKNDTRNPTVDRRKR
Length403
PositionMiddle
OrganismTrifolium pratense (Red clover)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Trifolium.
Aromaticity0.08
Grand average of hydropathy-0.700
Instability index43.53
Isoelectric point9.46
Molecular weight45103.84
Publications
PubMed=24500806
PubMed=28382043

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
DNA binding	GO:0003677	IEA:InterPro
metal ion binding	GO:0046872	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP18099
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.20|      22|      22|     338|     359|       1
---------------------------------------------------------------------------
  338-  359 (42.04/21.04)	PKPLP.EPTAALPASTQPQPPVP
  362-  384 (39.16/19.13)	PPPPPaTNVAATTSSTQAPSPMP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      81.40|      19|      19|     253|     271|       2
---------------------------------------------------------------------------
  235-  247 (14.38/ 7.56)	......RQRFLLELEFVQC
  253-  271 (34.69/29.13)	YIHYLAQNRYFEDEAFIGY
  274-  289 (32.33/26.63)	YLQYWQRPEYIK...FIMY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.02|      19|      19|     184|     202|       3
---------------------------------------------------------------------------
  184-  202 (32.48/23.01)	RGAKGKSEQGGGSAISTQP
  206-  224 (32.55/23.07)	RGGITEGTNGDGKVLEIVP
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP18099 with Med31 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) DSDSMASKAESESPTDTPPSPPNKTRVYHRRGAKGKSEQGGGSAISTQPKEIRGGITE
2) PTAALPASTQPQPPVPALPPPPPATNVAATTSSTQAPSPMPYGSVAKNDTRNPTVDRRKR
154
344
211
403

Molecular Recognition Features

MoRF SequenceStartStop
1) MPYGSVAKNDT
383
393