<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18091

Description Mediator of RNA polymerase II transcription subunit 15a-like protein (Fragment)
SequenceELSEMYQKIATKLQQHDSLPHQPKSDQLEKLKVFKMMLERLITFLQVSKSNISPSLKEKLGSYEKQIINFINTNRPRKLSSLQPGQLPPPHMHSMSQTQSQVTQVQSHENQMNNQLQTTNMQGPGATMLQNNITSMQHSSLSGVSTAQQHMMNTIQPSASLDSGQGNMSSLQQVPVSSLQQNSVTAPQQSNASSLSSQAGVNVIQQNLNPLQPGSGMLQHQQLKQQQEQQQQQMLQSQQFKQAQYQRQLMQRQQMLQQQLHQPAKQQLPAQLQTHQMQQLHQMNDVNDMKMRQGIGVKQGGFQQHIASNQRSGYPHQQLKQGPFTVSSPQLLQATSPQIPQHSSPQVDQQNHLPSLTKVGTPLQSANSPFVVPTPSPPLAPSPMPGDFEKPISGVSSISNAANVGHQQTGGAAAPAQSLAIGTPGISASPLLAEFTGPDGAHGNALVPSSGKSTVTEEPMDRLIKAVSSLTPAALSAAVSDISSVISMNDRIAGSAPGNGSRAAVGEDLVAMTNCRLQARNFITQDGANGTRRMKRCTNATPLNVVSSAGSVNDSIKQLTALEASDLESTATSNIKKPKIEANHALLEEIREVNQRLIDTVVSISDEEVNPTAAAAAAEGAEGTIVKCSYIAVALSPSLKALYASAQMSPIQPLRLLVPTNYPNCSPIFLDKFPVESSMENEDLSAKAKSKFSISLRGLSQPMSLKDIAKTWDVCARTVISEYAQQSGGGTFSSKYGSWEDCSTW
Length745
PositionTail
OrganismTrifolium pratense (Red clover)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Trifolium.
Aromaticity0.03
Grand average of hydropathy-0.494
Instability index59.08
Isoelectric point8.70
Molecular weight80439.76
Publications
PubMed=24500806
PubMed=28382043

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18091
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      70.98|      18|      18|     217|     234|       1
---------------------------------------------------------------------------
  230-  246 (25.39/ 9.53)	QQQQM.......lQSQQFKQAQYQ
  262-  278 (25.17/ 9.38)	QPAKQ.....QL..PAQLQTHQMQ
  279-  301 (20.42/ 6.19)	QLHQMndvndMK.MRQGIGVKQGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      85.16|      15|      15|     177|     191|       2
---------------------------------------------------------------------------
  145-  158 (22.78/10.70)	STAQ..QHMMNTI.QPS
  159-  175 (18.77/ 7.22)	ASLDsgQGNMSSLQQVP
  177-  191 (26.19/13.66)	SSLQ..QNSVTAPQQSN
  193-  207 (17.42/ 6.05)	SSLS.sQAGVNVIQQ.N
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.04|      14|      15|     101|     114|       4
---------------------------------------------------------------------------
  101-  114 (25.87/14.78)	QVTQVQSHENQM..NN
  117-  132 (22.17/11.53)	QTTNMQGPGATMlqNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.35|      23|      44|     303|     326|       5
---------------------------------------------------------------------------
  303-  326 (39.95/29.55)	QQHIASNQRSGYPHQQlKQGPFTV
  350-  372 (41.40/25.84)	QNHLPSLTKVGTPLQS.ANSPFVV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      88.23|      25|      26|     407|     431|       6
---------------------------------------------------------------------------
  377-  423 (28.98/13.96)	PPLAPSP...MpgdfekpisgvssisnaanvghQQTG..GAAAPAQSLAIGT
  424-  452 (32.60/16.70)	PGISASP...L....................laEFTGpdGAHGNALVPSSGK
  453-  479 (26.64/12.19)	STVTEEPmdrL......................IKAV..SSLTPA.ALSAAV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      78.36|      24|      27|      25|      49|       7
---------------------------------------------------------------------------
    5-   35 (31.73/16.03)	MYQKIATKLQQHDslphqpkSDQL.EKLKVFK
   37-   64 (28.55/19.07)	MLERLITFLQVSK....sniSPSLkEKLGSYE
   65-   83 (18.08/ 7.61)	..KQIINFINTNR.......PRKL.SSLQ...
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18091 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QRQQMLQQQLHQPAKQQLPAQLQTHQMQQLHQMNDVNDMKMRQGIGVKQGGFQQHIASNQRSGYPHQQLKQGPFTVSSPQLLQATSPQIPQHSSPQVDQQNHLPSLTKVGTPLQSANSPFVVPTPSPPLAPSPMPGDFEKPISGVSSISNAANVGHQQTGGAAAPAQSLA
2) TNRPRKLSSLQPGQLPPPHMHSMSQTQSQVTQVQSHENQMNNQLQTTNMQGPGATMLQNNITSMQHSSLSGVSTAQQHMMNTIQPSASLDSGQGNMSSLQQVPVSSLQQNSVTAPQQSNASSLSSQAGVNVIQQNLNPLQPGSGMLQHQQLKQQQEQQQQQMLQSQQFKQAQ
251
73
420
244










Molecular Recognition Features






MoRF SequenceStartStop




NANANA