<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18082

Description Mediator of RNA polymerase II transcription subunit 15a-like protein
SequenceMDNNNWRPNQGAEPNMDTNDWRGQLQPESRQRIVNKIMDTLKRHLPVSGQEGLHELRKIAQRFEEKIFTAATSQSDYLRKISLKMLTMETKSQGTTMANNIPPNQVGPSNKPPDPGLVMQSQVHNQGQQNPIALPNQPQSRQQLLSQNIQNNFAAQPNLPSVSGLAQTPIPNVGQNSNIQNMFNASQRQMQGRQQVVPQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQQQQQSQNPQQYLYQQQLFRHKLHMQSQQQQQQQQQQQQQQPQQQQQQQNLLQPNQLQSSQQSVMQQPSMMQTSSLSSIQHNQQSNNGQQSTQSMLQQHPQVIRQQQQQQNSIIHQQQTPMTQQSILPQQQQPQQQLLGPQTNTTNMQHTQMLGQQNNVGDVQQSQRLLAQQNNLSNLQKQQLINQQNNLSNIHPQLGNNVPGLQSQQVLGPQSGNSGMQTSQHSAHVLQQSKVPIQQQSQQGASNLLPSQAQQSQPQAPQQQLMSQIQSQPAQLQQQLGLQQQQPNPLQRDMQLYQSQRPLPETSSST
Length536
PositionTail
OrganismTrifolium pratense (Red clover)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Trifolium.
Aromaticity0.02
Grand average of hydropathy-1.331
Instability index93.97
Isoelectric point10.26
Molecular weight61244.74
Publications
PubMed=24500806
PubMed=28382043

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18082
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     243.24|      49|      53|     193|     243|       1
---------------------------------------------------------------------------
  194-  243 (95.30/14.98)	QQVVPQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQ...QQQQSQNpQQYLYQQ
  248-  293 (77.98/ 9.93)	HKLHMQSQQQQQQQQQQQQQQPQQQQQQQNLLQPN...QLQSS...QQSVMQ.
  294-  344 (69.96/ 6.30)	QPSMMQTSSLSSIQHNQQSNNGQQSTQSMLQQHPQvirQQQQQQN..SIIHQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     233.75|      54|      54|     367|     420|       2
---------------------------------------------------------------------------
  367-  420 (93.56/21.31)	PQ..TNTTNMQ..HTQMLGQ.QNNVGDVQQSQR..LLAQQNNLSNLQKQ.QLINQQNNLSNI
  422-  474 (74.41/14.73)	PQlgNNVPGLQ..SQQVLGP.QSGNSGMQTSQHsaHVLQQSKVP.IQQQ....SQQGA.SNL
  477-  531 (65.78/11.77)	SQ..AQQSQPQapQQQLMSQiQSQPAQLQQQLG..LQQQQPN..PLQRDmQLYQSQRPLPE.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.85|      15|      19|      56|      74|       5
---------------------------------------------------------------------------
   56-   74 (20.48/27.42)	LRKIAQrfeeKIFTAAT.SQ
   78-   93 (22.37/15.90)	LRKISL....KMLTMETkSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.55|      12|      28|     148|     159|       8
---------------------------------------------------------------------------
  148-  159 (23.15/14.59)	NIQNNF.AAQPNL
  178-  190 (19.40/10.73)	NIQNMFnASQRQM
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18082 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MDNNNWRPNQGAEPNMDTNDWRGQLQPESRQRIVNKIMDTLKRHLPVSGQEGLHEL
2) QQQQQQQNLLQPNQLQSSQQSVMQQPSMMQTSSLSSIQHNQQSNNGQQSTQSMLQQHPQVIRQQQQQQNSIIHQQQTPMTQQSILPQQQQPQQQLLGPQTNTTNMQHTQMLGQQNNVGDVQQSQRLLAQQNNLSNLQKQQLINQQNNLSNIHPQLGNNVPGLQSQQVLGPQSGNSGMQTSQHSAHVLQQSKVPIQQQSQQGASNLLPSQAQQSQPQAPQQQLMSQIQSQPAQLQQQLGLQQQQPNPLQRDMQLYQSQRPLPETSSST
3) RKISLKMLTMETKSQGTTMANNIPPNQVGPSNKPPDPGLVMQSQVHNQGQQNPIALPNQPQSRQQLLSQNIQNNFAAQPNLPSVSGLAQTPIPNVGQNSNIQNMFNASQRQMQGRQQVVPQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQQQQQSQNPQQYLYQQQLF
1
270
79
56
536
246










Molecular Recognition Features






MoRF SequenceStartStop




1) LQRDMQLY
2) QQYLYQQQLFRHKLHM
516
237
523
252