<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18067

Description Mediator of RNA polymerase II transcription subunit 16-like protein (Fragment)
SequenceAMTKIADSATNPNRQNNQELPNSNSKSNGSEFEEKKKKKNNEEAVTVTDNPVEEEEEEEVPMETEVEKEEDENSLSLSPATVFRIRLNQPTSNLLHIMSLPQISRNFSVVSWCGKLNAIACASETCTRIPSSTENPPFWIPIHIVIPERPTESAVFNVTADSPRDSVQFMEWSPACCPRALLIANFLGRVTIWTQPSQGPANLVVDTGCWLREHEWQQDIAVVTKWLSGVSMYRWLPSKSSATSNSKSVFEEKFVSQQPQTSARWPNFLCVCTVFSSGLVQLHWSQWPPSQNATPPKWFCTSKGLLGCGPNGIMAGDAIITDSGTLHVAGVPIVNPSTVVVWEVMPGPGNGFHLTPKTSINNGVPPLSPPNWSGFAPLAAYLFSWQDYLLSEEKQGKNQMDQNLGESIPLHCSPVSNFSAYVTPEAAAQYTETTTWGSGVTAVAFDPTRGGSVITVVIVEGQYMSPYYPDEGPSITGWRVQRWESSFQHVVLHPIFGNPTSSMGGKPPMQTVWQSKVDMSIPPTNGFNNHQTPPVEMNANVQKASESGSNNSKGVNFDPFDLPSDIRTLARIVFSAHGGEIAIAFLWGGVHVFSGLNFAPVANYQINVGSAIAVPAFSATSCCSASVWHDTSKGQTILKIIRVLPPAIPIGQVKANSSTWEHAIAERKSRFWWSLLVGVDWWDAVGCAQSAAEDGIVSLNGVIAVLDADFHSLPTAQHRQQYCPSLDRIKCRLLEGSNAQEVTAIVLDMQARLLLDMLEKGIESALINPSALVPDPWKASSETLSSIGLEAAAVEPALIPSIQAYVDSVLDLASHFITRLRRYAGFCHTLANHAVTAGTGSNRNMVASAAQNSTTPATNQGGENETTNSTGSKQMKAWVRGTFPGIPAVRLIGDCYFLHRLCRLVFFCFFFRRSQLPRNTSGVQRSADTNTQKPQHNAFVTVKVEENAKPVPSLVRSDDSQTGRVGEVVTGSKGCEELSLGRSRLGNGNAGRGYTYDEVKVLFLVLMDLCFRTSKLQHPLPVSQVGSSNIQVRLHYIDGNYTVLPEVLEASIGPHMKSMPRPRAADAAGRLLRELELYPPAEEWHQWNMVGGPWTDSDDEDYANDVSKLVSLNPLDSSSLENNDIYYGANGLWPRKRRMSERDAAFGLNTSEGLGAYLGIMGSRRDVISTLWKTGLGGVWYKCIRCLRQTSAFASPGSTNLPSQNDRESWWVSRWAYSCPMCGGRWARVV
Length1230
PositionTail
OrganismTrifolium pratense (Red clover)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Trifolium.
Aromaticity0.09
Grand average of hydropathy-0.261
Instability index43.27
Isoelectric point5.98
Molecular weight134831.59
Publications
PubMed=24500806
PubMed=28382043

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18067
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     236.52|      72|      80|     782|     859|       1
---------------------------------------------------------------------------
  782-  859 (107.34/96.58)	ETLSSIG.LEAAAVEPALIPSIQAyVDSVLDlaSHFITRLRRYAGFCHTLANHAVTAGTGSNRNmvaSAAQNSTTPATN
  865-  937 (129.18/93.84)	ETTNSTGsKQMKAWVRGTFPGIPA.VRLIGD..CYFLHRLCRLVFFCFFFRRSQLPRNTSGVQR...SADTNTQKPQHN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     591.73|     180|     537|     485|     687|       2
---------------------------------------------------------------------------
  485-  687 (281.09/172.27)	SSFQHVVLHPIFGNPT.......SSMGgkPPMQTvwqskvdMSIPPTNGFNNHQTPPVEMNANVQKASESGSNNSKGVNFDPFDLPSDIRTLARI....VFSAHGGEI..AIAFLWGGVHVFSGLNFAPVANYQINVGSAIAVPAfSATSCCSaSVWHdTSKGQTILKIIRVLPPAipiGQVKANSSTWEHAIAERKSrfWWsllvgVDWWdAVGC
 1027- 1219 (310.64/143.41)	SSNIQVRLHYIDGNYTvlpevleASIG..PHMKS.......MPRPRAADAAGRLLRELELYPPAEEWHQWNMVGGPWTDSDDEDYANDVSKLVSLnpldSSSLENNDIyyGANGLWPRKRRMSERDAAFGLNTSEGLGAYLGIMG.SRRDVIS.TLWK.TGLGGVWYKCIRCLRQT...SAFASPGSTNLPSQNDRES..WW.....VSRW.AYSC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     139.89|      40|      81|     299|     340|       3
---------------------------------------------------------------------------
  299-  340 (66.57/51.65)	FCTSKGLLGCGPNGIMAGDAIITDSGTLHVAgvPIVNPSTVV
  383-  422 (73.32/50.23)	FSWQDYLLSEEKQGKNQMDQNLGESIPLHCS..PVSNFSAYV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.85|       8|      74|     288|     298|       4
---------------------------------------------------------------------------
  288-  298 (14.76/10.98)	PPsqnATPPKW
  365-  372 (20.09/ 7.25)	PP...LSPPNW
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18067 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AMTKIADSATNPNRQNNQELPNSNSKSNGSEFEEKKKKKNNEEAVTVTDNPVEEEEEEEVPMETEVEKEEDENSL
2) SNRNMVASAAQNSTTPATNQGGENETTNSTGSKQ
1
841
75
874










Molecular Recognition Features






MoRF SequenceStartStop




1) SEFEEKKKK
30
38