<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18060

Description Mediator of RNA polymerase II transcription subunit 33A
SequenceMDLMESLAEIEKIYEIAIDGSDEEKLSAATILCGASLVRGWNVQEHTILFITKLLSPICLPNHTGTDNHLISQAPFLNVLLVGISPVDCVHIFSLHGLVPLLAAGLMQICEVFGSCDPDVSWTVATTGEKISHREVFSNAFTLLLRFWRFDHLPSEQVRVNAATPPLGSLFSPEYLLLVRNYKVASFGKSAKDSLKLKRLPKIIPFPKEPVFMDSFPKLNFWYRQHQQCIASIHSGLVPGGPVHQIVDALLCMMFRKVNDGSEPSTPTTLGSRSSSGSGSALDDALMKLKVPAWDILEAIPFVLDASLNACAYGRVSTRELATGLKDLADFIPASLVAIASYFSAEVTRGIWKPAFMNGTDWPSPAANLSLVEQQIKKILAATGVDVPSLAVDGDSPATLPLPLAAFVSLSITYKLEKGKERFLVLIGPALSAVASGCPWPCMPILTSLWIQKVKRWSDYFLLSASGTVFHHNKDAVVQLLKSCFTSTLGVGSTCMSNNGGVGALLGHGLASQVAGGISPVAPGILYLRAYRSIGDIMFLNKEIMSILMLSVRDITSSELHKGNARKQLKKFKYGMKCGEVSFVRYMARVKHAALLGASLVWISGGQKLVQSLIRDTVPSWFLSADMFEQDGGESGALVAMLSGYALAFFVMLSVAFAWGIDHCSVSPNQRAEVIWQHLEFLTSTLERNTSLRCHHATWRAYVSGFVSLLLSCTPMWVREVDAELLKRLSKGLRQLNEDELALQLLEIGGIGVMGAAAETIVKFEHML
Length768
PositionTail
OrganismTrifolium pratense (Red clover)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Trifolium.
Aromaticity0.08
Grand average of hydropathy0.264
Instability index37.45
Isoelectric point7.27
Molecular weight83698.54
Publications
PubMed=24500806
PubMed=28382043

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18060
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     213.56|      75|     132|     450|     525|       1
---------------------------------------------------------------------------
  428-  506 (125.93/83.80)	GPAL.SAVASGCPwPCMPILtslWIQKVKRWSDYFLLSASGTVFHHNKDAVVQLLKSCFTSTLGVGSTCMSNNGGVGALL
  507-  540 (27.44/16.47)	GHGLaSQVAGGIS.PVAPGI..lYLRAYRSIGDIMFL...........................................
  595-  639 (60.19/35.56)	...................................LLGASLVWISGGQKLVQSLIRDTVPSWFLSADMFEQDGGESGALV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.87|      21|     137|      89|     113|       2
---------------------------------------------------------------------------
   89-  113 (32.97/28.48)	CvhIFSLH.GLVPllAAGLMQI.....CEVF
  229-  255 (34.90/18.03)	C..IASIHsGLVP..GGPVHQIvdallCMMF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      81.28|      17|      72|     136|     152|       6
---------------------------------------------------------------------------
  136-  152 (32.81/17.85)	VFSNAFTLLLRFWRFDH
  170-  183 (17.18/ 6.41)	LFSPEYLLLVRNYK...
  211-  226 (31.29/16.74)	VFMDSFP.KLNFWYRQH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.20|      11|     241|     404|     414|      10
---------------------------------------------------------------------------
  404-  414 (19.19/12.78)	LAAFVSLSITY
  647-  657 (20.01/13.65)	LAFFVMLSVAF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18060 with Med33 domain of Kingdom Viridiplantae
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