<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18057

Description Mediator of RNA polymerase II transcription subunit 15a-like protein
SequenceMDPKNWRLNQDTELTIDTTDWRAQLLPDSRQQIINKVLDTLKKHLPVNGSEGLLELQKIAQRFEDKIFTAATDESDYQRKISLKILSMDSKSRNTTTANNMLSNDIGPSNKLLSQGNCGIAPISVVERNAIWNQRKTGLNSNSKTIPSEVWPSSSTDPLGQEKEYLSTQPDHFKRQKVSLGNPSYSSERTASGTPKAKDVFETWPSEKLKYEEELQRLTDQLKEKNELIAQLKEDNFNLATKSEGEKAELSAQLESSKKACENANTLLKDAQQSLEEVRKKHSEQHC
Length287
PositionTail
OrganismTrifolium pratense (Red clover)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Trifolium.
Aromaticity0.05
Grand average of hydropathy-0.947
Instability index35.25
Isoelectric point6.18
Molecular weight32489.90
Publications
PubMed=24500806
PubMed=28382043

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18057
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     171.51|      41|      95|      72|     112|       1
---------------------------------------------------------------------------
   72-  112 (65.22/35.73)	TDESDYQR.KISLKILSMDSKSRNTTTANNMLSNDIGPSNKL
  134-  165 (43.32/21.66)	......QR.KTG...LNSNSKTIPSEVWPSSSTDPLGQEKEY
  168-  209 (62.96/34.27)	TQPDHFKRqKVSLGNPSYSSERTASGTPKAKDVFETWPSEKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.81|      20|      20|     212|     231|       2
---------------------------------------------------------------------------
  212-  231 (32.20/19.67)	EEELQRLTDQLKEKNELIAQ
  234-  253 (32.60/19.99)	EDNFNLATKSEGEKAELSAQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18057 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KEDNFNLATKSEGEKAELSAQLESSKKACENANTLLKDAQQSLEEVRKKHSEQHC
2) NSKTIPSEVWPSSSTDPLGQEKEYLSTQPDHFKRQKVSLGNPSYSSERTASGTPKAKDVFET
233
142
287
203










Molecular Recognition Features






MoRF SequenceStartStop




1) EVRKKH
2) KISLKIL
277
80
282
86