<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18041

Description Mediator of RNA polymerase II transcription subunit 12-like protein (Fragment)
SequenceMLVISVLIRNNVPLLRATWFVKVTYLNQVRPGSAAISSGTADKVQLSRTEIWTKDVIHYLQTLFDEFFSKNTSHSTLHNRERSPQMPYAGTLLHKSDPLSSVSGGEEPSLHFRWRYITRLLQWHHAEGLILPSLVIDWVLNQLQEKDLLEVWQLLLPIIYGFLEIVVLSQTYVRALAGLTLRVIRDPAPVPDTFVALDCFPLPSSVVSHTMNDGSFVLKSTEAVGKIKNSLDDFGRIVSCIQKRGEDLAKSASPGNPGHCLAKVAKALDKSLMLGDLREAYNFLFEDFCDGTVSEGWIAKVSPCLRLSLKWFGTVNMSLIHSVFFLCEWATCDFRDFCTTPPCDIKFTGRKDLSHVHIAVRLLKMKLRDVKTSSRRTNRSIHRASQRHNQNYMTTGSSVISESPGPLHDIIVCWIDQHVVHKGEGLKRLHLFIVELIHAGIFYPLAYVRQLIVSGIMDMDANMVDLERRKRHSHILKQLPGHFMRDALAETGIADGPLLSEALQIYLTERRLILRSSPSELHDGANSAKVSTLKRKRYPASSKNGTSVVLTGPWKTAQTTVSSKSSKDGASIEEVKETISLLLQLPSSLSNLNSTGCVESEGSVRRPTWPNYGNIEPVEGTPGCEECRRAKRQKLSEERSSFVPGDDDTWWVKKGSKPSEPLKVDQPQKTTKQVTKSRQKNVRKMSLAQLAASRIEGSQGPSTSHVCDNKVSCPHHRTPIDGDALRSVDSIRTSSSRDIVFIGKALKRLRFVEKRVVAVWLLTVVKQAIEETEKNIGKTGQFGGAYSMEDDGNSIRWKLGEDELSAILYLIDISDDLVSAVKFLLWLMPRVLSSPSSTIHSGRNVLMLPRNVENQVCDVGEAFLLSSLKRYENILVAADLIPEALSLAMHRAATIIASNGRVSNLGATAFTRYLLKKYSNVASVIEWEQTFKSTCDARLSAELESVRSVDGESGLPFGVPAGVEDPDEFFRQKISGSRLPSRVGAGMRDIVQRNVEEAFQYLFGKDRKLYAAGTPKGHALEKWDNGYQIAQQIVMSLIDSIRQTGGAAQEGDPSLVLSAVSAIVGSVGPTLAKMPDFSSGNNQSSIVSLNYARCILRMHITCLRLLKEALGERQSRVFDIALATEASNVFAGVFAPSKASRAQFQMSSSEVHDT
Length1154
PositionKinase
OrganismTrifolium pratense (Red clover)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Trifolium.
Aromaticity0.07
Grand average of hydropathy-0.184
Instability index51.28
Isoelectric point8.98
Molecular weight128019.25
Publications
PubMed=24500806
PubMed=28382043

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18041
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     939.04|     326|     629|      12|     523|       1
---------------------------------------------------------------------------
  136-  523 (489.30/564.60)	IDWVLNQLQ..EKDLLEVWqlLLPII....................YGFLEivvlSQTYVR.ALAGLTLRVIRDPAPVPDTFVALDCFPL...PS..SVVSHTMNDGSFVLKSTEAVgkiKNSLDDFGR..IVSCIqKRGEDLaksaspgnpghclakvakaldksLMLGDL.REAYNFLFEDFCDGTVSEGWIAKV..SPCLRLSLKWFGTVnMSLIhsvfflcEW.....ATCDFR.............................DFCTTppcdiKFTGRKDLSHVHIAVRllKMKLRDVKTSSRR...TNRSIHRAS..QRHNQNYMTTGSSVISEspgplhdIIVCWIDQhVVHKG....EGLKRLHLFIVELIHAGIFYPLAYVRQLiVSGimDMDANMVDLE..RRKRHSHILKQlpgHFMRDALAE..TGIADGPLLSEALQIYL......TERRLILRSSPSELHD
  742- 1153 (449.74/240.36)	IGKALKRLRfvEKRVVAVW..LLTVVkqaieeteknigktgqfggaYSMED....DGNSIRwKLGEDELSAILYLIDISDDLVSAVKFLLwlmPRvlSSPSSTIHSGRNVLMLPRNV...ENQVCDVGEafLLSSL.KRYENI.......................LVAADLiPEALSLAMHRAATIIASNGRVSNLgaTAFTRYLLKKYSNV.ASVI.......EWeqtfkSTCDARlsaelesvrsvdgesglpfgvpagvedpdEFFRQ.....KISGSRLPSRVGAGMR..DIVQRNVEEAFQYlfgKDRKLYAAGtpKGHALEKWDNGYQIAQQ.......IVMSLIDS.IRQTGgaaqEGDPSLVLSAVSAIVGSVGPTLAKMPDF.SSG..NNQSSIVSLNyaRCILRMHITCL...RLLKEALGErqSRVFDIALATEASNVFAgvfapsKASRAQFQMSSSEVHD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     286.04|      90|     629|      12|     103|       2
---------------------------------------------------------------------------
   12-  103 (143.73/115.67)	VPLLRATWFVKvTYLNQVRPGSAAISSGTADKVQLSRTEIWTK.DVIHYLQTLFDEFFSKNTSHsTLHNRERSP..QMPYAGTLLHKSDPLSSVS
  643-  735 (142.31/104.99)	VPGDDDTWWVK.KGSKPSEPLKVDQPQKTTKQVTKSRQKNVRKmSLAQLAASRIEGSQGPSTSH.VCDNKVSCPhhRTPIDGDALRSVDSIRTSS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18041 with Med12 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DDDTWWVKKGSKPSEPLKVDQPQKTTKQVTKSRQKNVR
2) STGCVESEGSVRRPTWPNYGNIEPVEGTPGCEECRRAKRQKLSEERSSF
646
594
683
642










Molecular Recognition Features






MoRF SequenceStartStop




1) DTWWVKK
2) LKRKRY
648
533
654
538