<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17871

Description ATP-dependent DNA helicase
SequenceMESDLKQQLRLVDQELHQVQDQIQSLLQHQESLLEQQAELQQLIASCRDVAAHDENGNGPGASKSGGVNWSGSFEWDNRAADIRLNLFGIKSYRQNQHEIINAVMSGRDVIVIMAAGGGKSLCYQLPAMLRTGTALVISPLLSLIQDQVMGLTALGISASMLTSTTTKDEEKSIYKSLEKGEGDLKILYVTPEKVAKSKRFVSKLEKCNHGGRLSLIAIDEAHCCSQWGHDFRPDYKQLGILKKQFPRVPMIALTATATERVQTDLREMLQITRCEKFVSTVNRPNLFYEVREKKANGSAAIDDIASFILDKYSKKESGIVYCFSRKECEQVAAELRKRGISAAHYHADMKPETRSSVHMRWSTNKLQVIVGTVAFGMGINKPDVRFVIHHSLSKSLETYYQESGRAGRDGLPAHCLLYFRPADLPRQSSMVFAEMAGLHNLYAICRFCQSKQACRRAAFFRHFGEKIQKCNGMCDNCAFTKEVVDTDVTEHARSLVSMVKESNDVEQKLTILQLVEQWRSQTKKSDTDAQLAKDLSKDDVERVIVQLILDGILKEEFAHTAYATNAYVALGTGWRGLLQGTGNRKVKLEIVKGAQSAKKKSKANTAPISEEGMTFSGLGSALDDLRQNLAASHGGIFPHSVLTSQHISLLASQKPVTMEELEEVIGKRIAEQYGNEILVSITDYLEEHPADTENGGAWIAPKGKRAAEGPSTGQAKRVAKAPSDKPTKAPATRQSKRVAEGPAHDATKTRSIKNFLQKSTKADTDVGPSNTARSNQTPESFGPSTTKTPTKRLSLPRPSAISTPAPTTPKEEDVKQEAGKVPQSECIDLDSDSEGEEDQPALNGTVFKRENEEEDVIEETSSEEDEFSLFKRLKRQ
Length877
PositionUnknown
OrganismPhyscomitrella patens subsp. patens (Moss)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Bryophyta> Bryophytina> Bryopsida> Funariidae> Funariales> Funariaceae> Physcomitrium.
Aromaticity0.06
Grand average of hydropathy-0.512
Instability index45.01
Isoelectric point7.55
Molecular weight97014.80
Publications
PubMed=18079367
PubMed=29237241

Function

Annotated function 
GO - Cellular Component
chromosome	GO:0005694	IBA:GO_Central
cytoplasm	GO:0005737	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IBA:GO_Central
ATP binding	GO:0005524	IEA:UniProtKB-KW
four-way junction helicase activity	GO:0009378	IBA:GO_Central
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA duplex unwinding	GO:0032508	IBA:GO_Central
DNA recombination	GO:0006310	IBA:GO_Central
DNA repair	GO:0006281	IBA:GO_Central
DNA unwinding involved in DNA replication	GO:0006268	IBA:GO_Central
double-strand break repair via homologous recombination	GO:0000724	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17871
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     135.27|      32|      32|     698|     729|       1
---------------------------------------------------------------------------
  654-  691 (27.95/16.62)	QKPV.TmeeleEVI......GKRIAE...............qyGNEilVSI..TDYLE.EHPA
  692-  724 (51.39/37.81)	DTENgG.....AWIA...PKGKRAAE.................GPS..TGQ..AKRVA.KAPS
  725-  744 (34.50/22.54)	DKPT.K.....A................................PA..TRQ..SKRVA.EGPA
  745-  800 (21.44/10.73)	HDAT.K....tRSIKnflQKSTKADTdvgpsntarsnqtpesfGPS..TTKtpTKRLSlPRPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.67|      21|      26|     826|     850|       2
---------------------------------------------------------------------------
  826-  850 (31.86/29.59)	ECIDLDSDSEGEEDQPALngtvFKR
  853-  873 (34.81/21.31)	EEEDVIEETSSEEDEFSL....FKR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.99|      21|      26|       6|      31|       4
---------------------------------------------------------------------------
    6-   31 (29.93/36.46)	KQQlrlvdQELHQVQDQIQSLLQHQE
   35-   55 (35.05/27.11)	EQQ.....AELQQLIASCRDVAAHDE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      32.83|      11|      32|     504|     516|       5
---------------------------------------------------------------------------
  504-  516 (14.10/16.16)	NDVEQklTILQLV
  539-  549 (18.73/12.68)	DDVER..VIVQLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.07|      20|      25|     161|     180|       6
---------------------------------------------------------------------------
  161-  180 (32.22/18.51)	MLTSTTTK.DEEKSIYKSLEK
  187-  207 (27.85/15.15)	ILYVTPEKvAKSKRFVSKLEK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17871 with Med34 domain of Kingdom Viridiplantae
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