<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17865

Description Uncharacterized protein
SequenceMHRYPASAGGSSSGGPGGSGPPPARSSDPSFQNASNFTFTSRRAIPLQPYKLRCEREPLSARLGPPDFYPPTPNCAEEILNRDTTINGYKELIDGVEESKESVHTLTNNEALWARPNVNRYKESIRKRLRELNIATIRKRKAGQVYGVPLTGQLLAKAGVFPEHRTCGEDFRKKWVEDLSQRKRLRALAEHVPHGYQRRTIFEALIKHEVPLLRATWFIKIIYLNQVKPMSIGMSAGGPDKSQSKRVDLWTKNVLEYIQTLLDDLCQAGGASGSRSQVLPTRSALVEKEPDVLTKWRYVVRLAQWHYTEGLLNRTQVVDWTLKQLQDKESLEALELLLPIVLELIDGISSSQIHSRMLIELCLQWLRKLYSSGHVPSTGDSSQNNQVADTLVKLLQYLLLVVPDTFVALDCFPLPQPVSLGGSNSSAIESSSNDLGRVNSLDEDQSIFNAKGKRKTNFEVGVDESVDLIERRTASLARAVSPTLLRNNEGRIVQALDKALEKGDIAGAYRSVYDEEFCRSDNLPTDWRADVISRTTFNLSGPVNPSELYPVRFLCEWAVCDFRDSRGIVSKIVRKQCACRDMSRVYVAVSVLRMRLAEMDLKIGSHSSDPRLPEHFHCDFPMSRGGVPVQVRSRKSKKEHAVHARMGRSLKHNDSDFLALQAYSHNSVAIHDLVYAWLDQHDLWQGDSSDRLPLLLSELVREGLFSPEAYVRQLLCNGVLDKQSSATEIARASRHRHVLQHLPFPGELIVDGESNAGQSAAFRTYRIERRVALNVLGIPRHKHQTQETGVTGFLAQREDSRCSDLKPPLHDSRGRKRSQKRNLKIVELKQLIATSLRFPEDSLRILAKQLEPKAGAGSSGSKSFASNYTEIMDATPGCEQCSRAKRQKITEGKEWIASGSAIPSTEEEENWWFKKSPPKVVENPVKLEPPVKAAPKQTTRGRPKPVRKTQSLAQMASNRIDFNQGVSTTHMLEPKVSCPMHHPCLESGIAGDLRVLGEAMKRLRVLENQLLVSWLNIQVRSLLTNQGVTSPSSQSDRRLANGGISSIKSSDTSSWRLGEEQFSILVYIMDVGNDLRTLVQLLLWLLPISGTVSSLPASHVNHGIPAYVGIRGGSPCAVGETTLLSCLQRYENVMASMDMLPQALSAAMQRAANVMAAVPGGRAGCSALLCYVRDLLRKYGSLASVQAWEKCWKASCDQRLRAELEALKAGDGEGGFGLVSSMGDDRDDPIPPRLIGRLVRYGNVMKDIIQRNADAATQVIINKGREGGEDFMEDVFRHGHTLVVSVMNTVRQNSGGVSQNDAALVANAVSTIVNHAGQSVANVLENLGYNLSGEITATATSALQSGRRILQFYVYCLNLLKSAIDDRQIRMMEVAIANEANIIVQAGVGQFLGRSPRSQFHLSPEISDTNSTLANDSGGTLGRPTMAASAILALVAGLVVNGVTSLERMVSVLRVKDGLENLHLQKSGGLNANGKVSVMGGSAKAESVPEAHIHWFWVLIGDCRTILDGLVADLLGEPAVLGLARLQRSMALVTVFPPAYAIFAVALRRQQTIFANSMSREEAIIQAVTAAVNDIIAHEPFRDVCLRDTAALYRCMSLDPGEVKYAAMLDLQGFELYKKVSAMVPLRARLFLHALLDRKMPEDDMRGQNHTLNGPGQIEQVVQVLDELQAATFHWQWVELRLLLNEQVILEKLKIHPQSAQDAVQAAMQGPDRQQLDECEKTFTEVVLTRLLVRPDAAALYSEVVHLLGKALEDYLILHVKWVLENNDMLLGRKSLRQLLHNIAAKSFSIRPRQARTWDWQPPKQPHRDLAEMSEKKQASLQVGANSPEEGELEEEAMDWQKSDEKSFQQSSRAFSGSSCKPFATEKALADLVLPCLARSSLENRSGFAFELVKEMNNLEQHISNLTRSSGRPAASALPGSDGILGSKGSSVRRGPRIGMDVGSPGLGRRLTGSISEAVPVSLAALQTSVWLRLQFLLPLLPIILTEREQQSGPNKRQTLAPVLLRLLGTRAVQEEADVSCCWDPSSSNDFERNSQATSAAAAASACEPLFDRLLSILHALLSNTWPVWLKPRKISVKPLRDIPPFDKETAERMQVDLEHMQLPCGIRGRLQAAFPLLPPTPVTTVSAAPPQVPAAVFSLLQARGSNSTPASTMYPGSAQKSLYPAENNVGKLKAVALPDSEMEVDPWTLLEDGVGASNGPIGGGEVGNLKACAWLKGAVRIRRTDLTYIGAVDEES
Length2237
PositionKinase
OrganismPhyscomitrella patens subsp. patens (Moss)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Bryophyta> Bryophytina> Bryopsida> Funariidae> Funariales> Funariaceae> Physcomitrium.
Aromaticity0.06
Grand average of hydropathy-0.267
Instability index49.60
Isoelectric point8.65
Molecular weight246486.84
Publications
PubMed=18079367
PubMed=29237241

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17865
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.89|      23|      57|     550|     574|       4
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  550-  574 (37.73/29.03)	PvRfLCEWAVCDFRDSRGIVSKIVR
  610-  632 (49.15/28.13)	P.R.LPEHFHCDFPMSRGGVPVQVR
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.48|      22|     433|     248|     269|       7
---------------------------------------------------------------------------
  248-  269 (39.31/28.52)	DLWTKNVLEYIQTLLDDLCQAG
  682-  703 (38.16/27.42)	DLWQGDSSDRLPLLLSELVREG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.79|      41|      60|     297|     341|       8
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  297-  339 (67.52/59.30)	RYVVRLA.QW...HYTEGLLNRTQvvDWTL.KQLQDK..ESLEALELLLP
  356-  403 (54.27/33.94)	RMLIELClQWlrkLYSSGHVPSTG..DSSQnNQVADTlvKLLQYLLLVVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     234.48|      70|     893|     983|    1152|       9
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 1080- 1152 (118.75/160.66)	QLLLWLLPISGTVSSLPASHVNHGIPAYVGIRGGSPCAVGETTLLSCLQryeNVMASMDML..PQALSAAMQRAA
 1975- 2046 (115.72/32.87)	QFLLPLLPIILTEREQQSGPNKRQTLAPVLLRLLGTRAVQEEADVSCCW...DPSSSNDFErnSQATSAAAAASA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.78|      24|     984|     412|     437|      10
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  412-  437 (38.08/33.20)	FPLPQPVSlgGSNSSAIESSSNDLGR
 1400- 1423 (42.70/29.59)	FHLSPEIS..DTNSTLANDSGGTLGR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     183.81|      61|     482|     450|     519|      11
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  450-  519 (84.20/76.57)	AKGKRKTNfevGVDESVdlieRRTASLARAVSPTLLRNN........EGRIVQALDK.ALEKGdIAGAYRsVYDEEFCR
  933- 1002 (99.61/62.33)	AAPKQTTR...GRPKPV....RKTQSLAQMASNRIDFNQgvstthmlEPKVSCPMHHpCLESG.IAGDLR.VLGEAMKR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     167.54|      49|     181|    1449|    1498|      13
---------------------------------------------------------------------------
 1449- 1498 (82.74/60.56)	MVSvLRVKDGLENLHLQKSGGLNANGKVSVMGGSAKAESVPE.......AHIHWFWV
 1623- 1678 (84.81/57.57)	MVP.LRARLFLHALLDRKMPEDDMRGQNHTLNGPGQIEQVVQvldelqaATFHWQWV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     140.53|      43|    2048|      23|      73|      14
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   23-   73 (62.41/60.72)	PARSSdPSFQNASnftfTSRRAIPLQPYKLRCE.REPLSARLgpPdFYPPTP
 2079- 2122 (78.12/46.28)	PLRDI.PPFDKET....AERMQVDLEHMQLPCGiRGRLQAAF..P.LLPPTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     110.53|      24|     915|     896|     919|      15
---------------------------------------------------------------------------
  896-  919 (44.33/24.92)	IASGS.AI.PS....TEEEENWWFKKSPPK
 1783- 1808 (35.31/18.30)	IAAKSfSIrPR....QARTWDWQPPKQPHR
 1821- 1846 (30.89/15.06)	LQVGA.NS.PEegelEEEAMDW..QKSDEK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17865 with Med12 domain of Kingdom Viridiplantae
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