<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17849

Description Uncharacterized protein
SequenceMVADGSGKQRARPEWLQQYDLVGKIGEGTYGLVYLAKSKEPAHRGTKIAIKKFKQSKEGDGVSPTAIREIMLLRECIHENIVKLVNVHINHGDMSLYLAFDYAEHDLYEIIRHHREKINCSINAYTVKSLLWQILNGLNYLHSNWIIHRDLKPSNILVMGEGDEQGLVKIGDFGLARIFQAPLRSLSENGVVVTIWYRAPELLLGSRHYTSAVDMWAVGCIFAELLTLKPLFQGIEDKSSPNPFQLDQLDKIFKVLGNPTADKWPTLLTLPHWASNRQNIQTRKYDNPGLYSIVQLPPKSPGFDLLSKMLEYDPIKRITASQALEHDYFRNDPIPGRNSLVPPNAADKVVPYPQRPVDYSTDFDGTTAPPPPQMPNPSSMSGGSNQLHQSMNVNMQQQQHKVQNSNNMVVNPPVGMHGLNSSAGIYTQRGNPAVLLQQQQQQGLRRKEQSNVSYPGHYQPPNKSRRI
Length467
PositionKinase
OrganismPhyscomitrella patens subsp. patens (Moss)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Bryophyta> Bryophytina> Bryopsida> Funariidae> Funariales> Funariaceae> Physcomitrium.
Aromaticity0.08
Grand average of hydropathy-0.506
Instability index50.13
Isoelectric point9.11
Molecular weight52633.42
Publications
PubMed=18079367
PubMed=29237241

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IBA:GO_Central
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IBA:GO_Central

GO - Biological Process
protein phosphorylation	GO:0006468	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17849
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     128.66|      38|      39|     370|     407|       1
---------------------------------------------------------------------------
  356-  400 (66.32/33.95)	PVDYSTDfdgttapPPPQMPNPSSMSGGSNQLHQSMNVNMQQQQH
  401-  442 (62.34/31.52)	KVQNSNN...mvvnPPVGMHGLNSSAGIYTQRGNPAVLLQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.45|      18|      42|     225|     243|       2
---------------------------------------------------------------------------
  225-  243 (29.41/18.81)	LLTLkPLF....QGIEDKSSPNP
  267-  288 (31.04/15.76)	LLTL.PHWasnrQNIQTRKYDNP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17849 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HDYFRNDPIPGRNSLVPPNAADKVVPYPQRPVDYSTDFDGTTAPPPPQMPNPSSMSGGSNQLHQSMNVNMQQQQHKVQNSNNMVVNPPVGMHGLNSSAGIYTQRGNPAVLLQQQQQQGLRRKEQSNVSYPGHYQPPNKSRRI
326
467










Molecular Recognition Features






MoRF SequenceStartStop




1) KIAIKK
47
52