<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17844

Description Uncharacterized protein
SequenceMVANGSVKQRTRPEWLQQYELVGKIGEGTYGLVYLARSKEPAHRGTKIAIKKFKQSKEGDGVSPTAIREIMLLRECVHENIVKLVNVHINHGDMSLYLAFDYAEHDLYEIIRHHREKVTCSINPYTVKSLLWQILNGLNYLHSNWIIHRDLKPSNILVMGEGEEQGVVKIGDFGLARIFQAPSRPLSDNGVVVTIWYRAPELLLGSKHYTSAVDMWAVGCIFAELLTLKPLFQGIEDKSSPSPFQFDQLDKIFKVLGNPTADKWPTLTTLPHWAQNRQSIQSRKYDNPGFYSIVQLPPKSPGFDLLSKMLEYDPIKRITAAQALEHEYFRNDPIPGRNSLVPANSADKVVPYPQRPVDYSTDFDGTTAPPPSQMPNSSNMSGSSNQLHPSMNVNMQQQHRIQNSNTLSVNQPVGMHGMNSSSNMYIQRGNATVPQQQPQQQQGLRRKDQTNVGYPGHYQPPNKSRRI
Length467
PositionKinase
OrganismPhyscomitrella patens subsp. patens (Moss)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Bryophyta> Bryophytina> Bryopsida> Funariidae> Funariales> Funariaceae> Physcomitrium.
Aromaticity0.08
Grand average of hydropathy-0.551
Instability index50.31
Isoelectric point9.20
Molecular weight52789.41
Publications
PubMed=18079367
PubMed=29237241

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IBA:GO_Central
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IBA:GO_Central

GO - Biological Process
protein phosphorylation	GO:0006468	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17844
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.87|      13|      17|     351|     365|       1
---------------------------------------------------------------------------
  351-  365 (23.34/18.76)	PYP.QRPvdYSTDFDG
  369-  382 (23.53/12.10)	PPPsQMP..NSSNMSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      79.52|      16|      17|     384|     399|       2
---------------------------------------------------------------------------
  384-  399 (30.51/18.43)	SNQLHPSMNVNMQQQH
  404-  416 (22.34/11.60)	SNTLSVNQPVGM...H
  422-  437 (26.68/15.23)	SNMYIQRGNATVPQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.46|      17|      17|     180|     196|       4
---------------------------------------------------------------------------
  180-  196 (30.60/20.66)	QAPSRPLSDN..GVVVTIW
  198-  216 (24.86/15.51)	RAPELLLGSKhyTSAVDMW
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17844 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HEYFRNDPIPGRNSLVPANSADKVVPYPQRPVDYSTDFDGTTAPPPSQMPNSSNMSGSSNQLHPSMNVNMQQQHRIQNSNTLSVNQPVGMHGMNSSSNMYIQRGNATVPQQQPQQQQGLRRKDQTNVGYPGHYQPPNKSRRI
326
467










Molecular Recognition Features






MoRF SequenceStartStop




1) KIAIKKF
2) YQPPNKSR
47
458
53
465