<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17841

Description Uncharacterized protein
SequenceMHRYPAAAGGSSSGGPGGGGPPPARSSDPSFQNSSNFTFASRRAVPLQPYKLRCEREPLSARLGPPDFYPPTPNCAEEILNRDTTVNGYKELIAGVEENRESSLSLTDSDALWAKPNVNRYKESIRKRLRELSIALIRKRKAGQVYGVPLSGNLLAKSGVFPEHRTCGEDFRKKWIEDLSQRKRLRALAEHVPHGYQRRTIFEALIKHDVPLLRATWFIKIIYLNQVKPMSIGMSAGGPDKSQSKRVELWTKNVLEYTQSLLDDLCQTGGASGSHSQILSVRGDSVENEPDLLAKWRYIVGLAQWHYTEGLLNRTQVVDWALKQLQEKESVEALELLLPILLELVDGISMSQTHSRMLVELCLQWLRKLYPLGHVPSIGDNSRNNRVADTLVKLLQYLVLVIPDTFVALDCFPLPQCVSLGGSESSAIESSSNDLGRVNSVVEDRSIMYAKGKRKTYSEVGVVESVDLIQKRTASLASAVSPTLLRNNEGKIVQALDKALEKGDIAGAYRSVYDDEFCSSDNLPADWRADVTSRTAFNLSGPVNPSELYPVRFLCEWAVCDFRDCRGIVSKTIRKQSACRDMSRVYVAVSVLRMRLAEMDSKIGPHSPDTRLPEHFDSCDPLSRGGLPVHVRNRKSKKGQAVHAPMDHSVEFSSGNFSALHNHSHNSIAIHDLIYAWLDQHELWQGDSSDRLPLLLSELVREGLFSPEAYVRQLLCNGVLDRQSTATEVARASRHRHVLQQLPFPGGLIGDAVSNIDSRQSVAFRMYRIERRLALDGLGIRRHEQHIQGTGATGSIVRREGSKGSESRPSVHEFRDRKKRQKRNFMIAELKQLIAINLQLPEYSFRMVAKQLEMKVGVGSRGSKRFSYNNMGTRDATPGCEECSRAKRQKTAEGKEWIATGSMTPLEDEDENWWFKKGPQKVVENPIKLEPPVKVAPKQTTRGRPKPVRKTQSLAQMATNRLDSNLGASTTHVLEPKISCPIHHSSLEGGTAAQLKTSHYSKMTGDLRAIGEAMKRLRVVENQMIVSWLDSQLRSILTNQGITSPSLQGDRRLANGGVSNTDSADPGTWRLGEEQFSIIVYIMDVGNDLHTLMQLLLWLLPISGTISSPSVIHVNHGIPAYVGSRDGSSCAVGETALLSCLQRYEGVLASMDMLPQALSAVVQRAANVMAAVPGGRAGCSALLCYVRDLLRKYGSLANVQAWEKSWKASCDQRLRAELEALKGDTEGGFGLVSSMGDDRDDPVPPRLTGRLVRYGNAMKEIIQRSADAITQIIINKERDVGGEPVEDVLRHGHTLLVGVMNIIKQNSGGVSQNDVALLANAVSTIVNHAGQSVANVLENLGYNAPGETTATALSALQAGRRTLQFYVYCLHLLKGAVDDRTFRMLEVAIANEANTIVQAGVGHFPGRAPRSQFHLSPETPDTNSTLASDPGGTLGRPTMAASAVLALVTGLVVNGVTTLERMVSVLRVKDGLENMYLQKSGSLNSNGKVSSMGGNAKTESVPEAHIHWFRVLIGDCRTVLEGLVADLLGEPAVLGLARLQRSLALVTVFPPAYAIFSVALRRQQTIFVNNMSREEAIIQAVTVAGNDVVAHEPFRDVCLRDTTSLYRCLSGDSGDSKYAAMLDVQGFELYKKVSAMVPLRARLFLHALLDRKMPEDDTRSQNRSHTSNGPGQIEQVVQVLDELQAATFHWQWIELRLLLNEQVILEKLKIHPQNAREAVLAAMQGPERQQLDECEKTFTEILLTRLLVRPDAAALYSEVVHLLGKALEDYLILHVKWVLENNDMLLGRKSLRQLLDNIAAKSVPVRARQVRALNWQPPRPLHRDSEEAAEKKQWSLQGGAASPEEGELEDERMDWQKSDEKPSRQSSGTLSGLTCKPFATEKALADLVLPCLARSSMDNRNGFAHELVKEMNNLEQHISNLTRNSGRTIASTSPGGDGILGSKGSSVRRGGRSGMDVGSPGLGRRFTGPVPEAVPVSPAALQTSVWLRLQFLLPLLPIILAEREQQSVPNKRQTLAPVLLRLLGTRIVQEETDPLCCWDPSSSNDFERNSQATSAAAAASAGEPLFDRLLSILHALLSNTWAVWLKPRKGSVKPLRDIPPFDKEAAERMQVDLEHMQLPCGIRARLQAAFPLLPPTPVTTVSAAPPQVPVSVLSQLQVKGFNSTLGVSTTYPGSAQKSLYPLENNAGKLKAVTSADSEMEVDPWTLLEDGVGASSGPIGSGEVGNLKACAWLKGAVRVRRTDLSYIGAVDEEP
Length2253
PositionKinase
OrganismPhyscomitrella patens subsp. patens (Moss)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Bryophyta> Bryophytina> Bryopsida> Funariidae> Funariales> Funariaceae> Physcomitrium.
Aromaticity0.06
Grand average of hydropathy-0.293
Instability index47.64
Isoelectric point8.67
Molecular weight247653.67
Publications
PubMed=18079367
PubMed=29237241

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17841
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      69.39|      15|      15|    1039|    1053|       1
---------------------------------------------------------------------------
 1022- 1037 (19.65/ 6.76)	NQMI..VS.WLDSQLRsiL
 1039- 1053 (27.49/12.11)	NQGI..TSPSLQGDRR..L
 1055- 1071 (22.25/ 8.54)	NGGVsnTDSADPGTWR..L
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     106.53|      25|      46|    1163|    1188|       2
---------------------------------------------------------------------------
 1142- 1162 (26.65/ 9.16)	QRYEGVLASMDMLPQALSAVV....
 1163- 1187 (41.97/21.07)	QRAANVMAAVPGGRAGCSALLCYVR
 1212- 1236 (37.91/12.86)	QRLRAELEALKGDTEGGFGLVSSMG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.72|      22|      60|     541|     567|       3
---------------------------------------------------------------------------
  541-  567 (33.59/39.35)	GPVNPSELYPVRFlcewAVCDFRDcRG
  604-  625 (45.13/29.41)	GPHSPDTRLPEHF....DSCDPLS.RG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     345.41|     110|     163|    1628|    1742|       4
---------------------------------------------------------------------------
 1628- 1742 (170.82/106.85)	ELYKKVSA.MVPLRARLF..LHALLDRKMPEDDTRSQNRSHTSNGPGQIEQVVqvlDELQAATFHWQWIELRLLLNEQVILEKLKIHPqNAREAVLAAMQGP..ERQQLDEcEKTFTEIL
 1793- 1907 (174.59/95.06)	QLLDNIAAkSVPVRARQVraLNWQPPRPLHRDSEEAAEKKQWSLQGGAASPEE...GELEDERMDWQKSDEKPSRQSSGTLSGLTCKP.FATEKALADLVLPclARSSMDN.RNGFAHEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.10|      29|      48|     734|     762|       6
---------------------------------------------------------------------------
  734-  762 (50.71/35.23)	RHRHVLQQLPFPGGLI.GDAVSNIDSRQSV
  782-  811 (45.39/30.56)	RHEQHIQGTGATGSIVrREGSKGSESRPSV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.34|      24|     479|     138|     161|       8
---------------------------------------------------------------------------
  138-  161 (41.55/24.99)	RKRKAGQVYGVPLSGNLLAKSGVF
  634-  657 (43.78/26.76)	RKSKKGQAVHAPMDHSVEFSSGNF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.81|      17|      20|    1975|    1994|       9
---------------------------------------------------------------------------
 1978- 1994 (31.41/24.05)	PAAL....QTSVWLRLQFLLP
 1997- 2017 (25.40/ 9.36)	PIILaereQQSVPNKRQTLAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     172.84|      55|      59|    1428|    1483|      15
---------------------------------------------------------------------------
 1428- 1483 (85.24/61.15)	SDPGGTlGRPTMAASAVLALVTGLVVNGVTTLERMVSVLRVKDGLENMY.LQKSGSL
 1490- 1545 (87.59/58.42)	SSMGGN.AKTESVPEAHIHWFRVLIGDCRTVLEGLVADLLGEPAVLGLArLQRSLAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.21|      14|      15|    1938|    1951|      22
---------------------------------------------------------------------------
 1938- 1951 (25.22/13.66)	GI.LGSKGSSVRRGG
 1954- 1968 (22.99/11.71)	GMdVGSPGLGRRFTG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17841 with Med12 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GSRGSKRFSYNNMGTRDATPGCEECSRAKRQKTAEGKEWIATGS
2) GTGATGSIVRREGSKGSESRPSVHEFRDRK
3) LEQHISNLTRNSGRTIASTSPGGDGILGSKGSSVRRGGRSGMDVGSPGLGRRFTGP
4) MHRYPAAAGGSSSGGPGGGGPPPARSSDPSFQNSSNFT
5) NPIKLEPPVKVAPKQTTRGRPKPVRKTQSLAQMATNRLDSNLGAST
6) NWQPPRPLHRDSEEAAEKKQWSLQGGAASPEEGELEDERMDWQKSDEKPSRQSSGTLSGLTC
859
789
1914
1
925
1814
902
818
1969
38
970
1875










Molecular Recognition Features






MoRF SequenceStartStop




NANANA