<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17837

Description Uncharacterized protein
SequenceMDNSSWRSSLAHDSRQKIVKRIMDTLQRHMPVAGQDGVEELLKIAWRFEEKIFQAATDQQDYLRKISLKMLSLETKANGNPLQRPPPGAQGATGAPGAPGTGGLQMRSVAALGNGVQLGGQNQQQQQLQQRQQQQQLLTQSLQGNGAGGIQTPATGLTSNLSAMTGVPQNPMAAMAGQVMNPTMMNNRLQQMQQQQRQAVQQQQVSQQQQQNNQQQQILYQQQQRLQQHQAMMKQKLQQQSLLQHQQHQSLQQQQQQQQVSSLQQQQQQPVSQLMNQNNAALQQQQQQMLQQQMMQSKQQQAQLQQQQQQQQQQQQQQQQQSQQQQVATPTQSQQSQQSQPIGQQPGQQGQLGQQQSGSNQQPQQRIGQSGGLQQQQQQQQQQQQQTNMLLQAQQQRAIPDTSTASVESSAQSGPTGAAAGNVDQRELVWNKLQLLKDKYLQDMTELFRMLSTRSTQPMPAEQLQKLKHYKDVLHRMIPYLRVPKDRVPKEFNQDKVDAFEKQIVSIMETFKKRRQPQAPLPAGPTVSGPPPTQQTPAQAVPAQHPDQVSMAQASQQQPSQMLQNGQPLQQIPSNSQGIQLVQQQQQQQQQQHQQQHQQLQQQQHQQQLQHQQQLLSQMQQEKQVQHQLAGIGSQAAGTMIQPTNNALTSLQQNPGTLQQTLAGAPLQTTVVPTSQSVGAAMPTSSTGSMGQSALTSLSANPNVPGNASQSGMNLPQSDGVSSQSGVNTYQQSLNNTLQQSVVGGLQQNGSSVTSLPNQNNALQQQILKQQQEQHQQQLLQAQHQRMIQQDLQQRNLQQQQQQMLQQQQQQRQIQQNHQKNQVAQLQALQAQQQQQQQQQQQLLDPYADVKIDASLKAKQASVKQALLQQQQQQQQQQQQQQQQQQQLKQRHIMQFQQQQQSQKTGSPQLVTSPQISQVMSPQPDQAFNAMQMHKTGTPPQSFRIPSPSALPTTPTQDDADHKGLTPAPSSGTPGTVQAFQTAIRNTPGMSGSINTPGMSVSPLMENTLSPSPAQLLMVHDAAQAFSPGTPLMDKTNSTEPPLERLKRKVDSMPREILKKAVNEMNDMVSCGDKLGASAPGTGSRAAIGEDLSAKTRSTMQARALSHDNCNVSKKRRRVDSIALNMISSDGTISNTLHRSCYNTDAENHMVSHINSPLVKITASLEEEIRDINSRLIDTVVEVSPEATEENAAQGGNGIVLSCCYKGNALSPNISFLQSKEYALVSRASLYLTVPPTYPVHFPDIWFDQSNPQANHHCFKGAREEFMRNLRCLPPPVSLASIATSWDECARKSLTEYAHQQGGGSFTTAYGTWETTAHQIAC
Length1322
PositionTail
OrganismPhyscomitrella patens subsp. patens (Moss)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Bryophyta> Bryophytina> Bryopsida> Funariidae> Funariales> Funariaceae> Physcomitrium.
Aromaticity0.03
Grand average of hydropathy-0.931
Instability index79.34
Isoelectric point9.37
Molecular weight146796.92
Publications
PubMed=18079367
PubMed=29237241

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IBA:GO_Central
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17837
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     621.21|      68|      68|     284|     351|       1
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  167-  225 (81.49/10.80)	V.PQNPMaaMA.......GQVMNPT.M...MNNRLQQMQQQ..Q.RQAVQQ..QQ..VSQ..QQQ...........QNNQQQQ.IL...YQ..QQQR
  228-  280 (79.83/10.38)	Q.HQ...............AMMKQKlQ...QQSLLQHQQHQ..SLQQQQQQ..QQ..............VSS....LQQQQQQPVS...QLMNQNNA
  284-  351 (138.28/24.99)	Q.QQQQM..LQ.......QQMMQSK.Q...QQAQLQQQQQQ..QQQQQQQQ..QQ..QSQ..QQQVATPTQS....QQSQQSQPIG...QQPGQQGQ
  354-  425 (87.14/12.21)	Q.QQSGS...N.......QQPQQRI.G...QSGGLQQQQQQ..QQQQQQQT..NMllQAQ..QQR.AIPDTStasvESSAQSGPTG...AAAGNVDQ
  581-  642 (77.40/ 9.77)	LvQQQQQ..QQ.......QQ..QHQ.Q...QHQQLQQQQHQ..QQLQHQQQllSQ..MQQ..EKQV..............QHQLAGigsQAAGTMIQ
  782-  838 (81.38/10.77)	A.QHQRM..IQ.......QDL.........QQRNLQQQQQQmlQQQQQQRQ.iQQ..NHQ..KNQVA.QLQA....LQAQQQQ.......QQ....Q
  839-  905 (75.68/ 9.34)	Q..QQQL..LDpyadvkiDASLKAK.QasvKQALLQQQQQQ..QQQQQQQQ..QQ..QQQlkQRHIM...QF....QQQQQSQK............T
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     239.57|      49|      62|     946|     994|       2
---------------------------------------------------------------------------
  907-  946 (67.90/34.19)	SPQ.LVTSPQISQV....MSPQP.............DQ......................AFNAMQMHKTGTPPQSFRIP
  947-  995 (84.18/44.42)	SPSALPTTPTQDDADHKGLTPAP.............SSG............TP......GTVQAFQTAIRNTPGMSGSIN
  996- 1058 (56.31/26.91)	TP.GMSVSPLMENT....LSPSPaqllmvhdaaqafSPG............TPlmdktnSTEPPLERLKRKVDSMPREIL
 1059- 1102 (31.19/11.13)	KKAVNEMNDMVSCGDKLGAS.AP.............GTGsraaigedlsakTR......STMQA................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      91.07|      24|      62|     438|     461|       3
---------------------------------------------------------------------------
  438-  461 (44.53/26.38)	DK....YLQDMTELF..RMLS.......TRSTQ.PMPA
  467-  485 (26.21/12.15)	LK....HYKDV..LH..RMIP......yLR.....VPK
  486-  523 (20.33/ 7.59)	DRvpkeFNQDKVDAFekQIVSimetfkkRRQPQaPLPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      78.26|      16|      62|    1141|    1156|       4
---------------------------------------------------------------------------
 1141- 1156 (29.73/22.44)	CYNTDAENHMVSHINS
 1159- 1174 (21.76/14.37)	VKITASLEEEIRDINS
 1204- 1219 (26.77/19.45)	CYKGNALSPNISFLQS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     224.03|      44|      45|     649|     693|       5
---------------------------------------------------------------------------
   78-  117 (57.08/18.23)	..NGNPLQRP.PPGAQGATGAPGAP.....GTGGLQMR.....SVAALGNGVQ.
  531-  564 (33.18/ 6.67)	...........PPTQQTPAQAVPAQhpdqvSMAQASQ.........QQPSQMLQ
  661-  703 (53.45/19.20)	TLAGAPLQTTvVPTSQSVGAAMPTS.....STGSMGQS..alTSLSANPN....
  704-  732 (36.48/ 8.43)	.VPGN........ASQS.GMNLP.Q.....SDGVSSQS..gvN.......TYQQ
  733-  765 (43.83/11.93)	SLNNT.LQ.......QSV.............VGGLQQNgssvTSLPNQNNALQQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17837 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ETKANGNPLQRPPPGAQGATGAPGAPGTGGLQMRSVAALGNGVQLGGQNQQQQQLQQRQQQQQLLTQSLQGNGAGGIQTPATGLTSNLSAMTGVPQNPMAAMAGQVMNPTMMNNRLQQMQQQQ
2) LLQQQQQQQQQQQQQQQQQQQLKQRHIMQFQQQQQSQKTGSPQLVTSPQISQVMSPQPDQAFNAMQMHKTGTPPQSFRIPSPSALPTTPTQDDADHKGLTPAPSSGTPGTVQAFQTAIRNTPGMSGSINTPGMSVSPLMENTLSPSPAQLLMVHDAAQAFSPGTPLMDKTNSTEPPLERLKRKVDSMPREILKKAVNE
3) LQQSVVGGLQQNGSSVTSLPNQNNALQQQIL
4) QIVSIMETFKKRRQPQAPLPAGPTVSGPPPTQQTPAQAVPAQHPDQVSMAQASQQQPSQMLQNGQPLQQIPSNSQGIQLVQQQQQQQQQQHQQQHQQLQQQQHQQQLQHQQQLLSQMQQEKQVQHQLAGIGSQAAGTMIQPTNNALTSLQQNPGTLQQTLAGAPLQTTVVPTSQSVGAAMPTSSTGSMGQSALTSLSANPNVPGNASQSGMNLPQSDGVSSQSGVNTYQQSL
5) SQQQQVATPTQSQQSQQSQPIGQQPGQQGQLGQQQSGSNQQPQQRIGQSGGLQQQQQQQQQQQQQTNMLLQAQQQRAIPDTSTASVESSAQSGPTGAAAGNVDQ
6) VSCGDKLGASAPGTGSRAAIGEDLSAKTRSTMQARALSHDNCN
74
867
738
503
322
1069
196
1064
768
734
425
1111










Molecular Recognition Features






MoRF SequenceStartStop




NANANA