<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17804

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMRGPLSSMTSKTSSLKALLLRAWRERWSDLQWGIHIKTILPRGVSGDVYNLADCILQQALVGPGPNQLVVSYLKHSLSSQLVSYAAVLQRISKYDGFHKPHCIISLLEFLEAIQGGITCRGKPEEGLLAASVLSIVQWLLTCMQHALKNMPELRNGNIELTSMLDKPAVILTEILKCDFLVAMLYLAKHECRDIYHEVVKKCHELEALLSQNSFQPSVPIGDSMRKLRQLDISSDGGVDGKPDDTEPVTYCLQALLAIEVLLNPSSDTQMFVNELLMVQRLKGYSMPRLYSEVMRACLITLNDALGMSIESQWGAFTFLKVPHILRQLHFTIRGGENGDRQQEKLEFSQDVVDALELLLQYTPLLDIMDAKCSCNCIECLLKELLRNGLVTESHVAHFTSKRCVLPPALTFQDEREAVTATVQKLDQATSPASSIPKVIVRAEPTLARILKTLDADYVKVQEALLSVLCQVLTGKSFELILAVAAVEGKLRTFVTKLLKFNECSKQIGGEGGKASQTRALLFDVTFLMLCSIVHTYGPEVVLSEEGGDSFFEQWVRECMVERGRPKSPDQMLQHCDPARVDALLAQFNSADGDFKTSQVKWHEVCLHVPAAIREVLLAWEHGAVTANDVKRILDAMRSRMCCLPVCAAAWLCSYMQILHQDALLKPLNMVQQFLTPLSNEDMSQQDNFKERSGLMFQIIRKMQYDVHPPTQSKVKVMTLSHSIISRQPISEQLDSVWAAIQQRGWVNIEATHSLESLLNTGGSQWFVTNLVKEVLKFRYQEDLDRAVDLAFGVFHLDIEHCTLALLLQVLPQYLYNRLQSEELVEPQASALAKLCAYCVFAALEFQNNATPGHVNSRKRSRRDLEGEDLEGLCPSSKLLRLSSGVTEAADTAALFGTTASSSQNSNQPYSNSNQPVTIKEPLQKALNDLFHTFTVIAGRDGEISQQTHFVCKFLQFVVRCGRDRTRLVLQGMPNTLVPCLLRSLPDLFTMDLLLKLYDINTVAGRKATARDLCMLRNMNLKMSMKDVL
Length1028
PositionTail
OrganismCryptotermes secundus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Polyneoptera> Dictyoptera> Blattodea> Blattoidea> Termitoidae> Kalotermitidae> Cryptotermitinae> Cryptotermes.
Aromaticity0.07
Grand average of hydropathy-0.025
Instability index46.36
Isoelectric point6.45
Molecular weight115100.26
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17804
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.84|      11|      22|     930|     940|       1
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  930-  940 (21.52/11.26)	FHTFTVIAGRD
  953-  963 (22.32/11.89)	FLQFVVRCGRD
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.55|      21|      22|     163|     184|       2
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  164-  184 (36.20/22.20)	LDKPAV..ILTEIL.KCDFLVAML
  186-  209 (29.35/12.16)	LAKHECrdIYHEVVkKCHELEALL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.50|      10|      22|     110|     119|       3
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  110-  119 (18.35/11.11)	LEAIQGGITC
  133-  142 (19.15/11.92)	LSIVQWLLTC
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     386.54|     125|     279|     240|     374|       6
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  240-  317 (100.73/66.46)	..................................................................................................................................................................................................GKPDDTEPVTYcLQALL...............AIEVLLNPSSDTQMF...VNE........LLMVQRLKGYSM.PRLYSEVMRACL...ITLNDALGMSIESQWGAFT
  318-  374 (35.97/37.52)	FLKVPHILRQLhftIRGGENGDRQQEklefsqDVVDALELLLQYTPLLDIMDAKCSC.....................................................................................................................................................................................................................................................
  512-  595 (68.10/37.70)	.........................................................nciecllkellrnglvteshvahftskrcvlppaltfqdereavtatvqkldqatspassipkvivraeptlarilktldadyvkvqeallsvlcqvltgksfelilavaavegklrtfvtkllkfnecskqiggegGKASQT.......RALLfdvtflmlcsivhtyGPEVVLSEEGGDSFFeqwVRE.........CMVERGR.....PKSPDQMLQHCD...PARVDALLAQFNSADGDFK
  605-  739 (181.73/121.52)	CLHVPAAIREV...LLAWEHGAVTAN......DVKRILDAMRSRMCCLPVCAAAWLC.........................................................................................................................................SYMQILHQDAL.LKPLN...............MVQQFLTPLSNEDMS...QQDnfkersglMFQIIRKMQYDVhPPTQSKVKVMTLshsIISRQPISEQLDSVWAA..
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     143.62|      47|     696|      58|     107|       7
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   58-  107 (77.18/60.04)	QALVGPGPNQ.LVVSYLKHSLSsqlVSYAAVLQRISK..YDGFH..KPHCIISLL
  755-  806 (66.44/43.85)	ESLLNTGGSQwFVTNLVKEVLK...FRYQEDLDRAVDlaFGVFHldIEHCTLALL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     118.75|      38|     541|     431|     469|       9
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  431-  469 (57.90/44.73)	PASSIPkVIVRAEP...TLARILKTLDADYVKVQEALLSVLC
  973- 1013 (60.85/42.24)	PNTLVP.CLLRSLPdlfTMDLLLKLYDINTVAGRKATARDLC
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17804 with Med24 domain of Kingdom Metazoa
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