<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17802
Description |
Mediator of RNA polymerase II transcription subunit 13 |
Sequence | MRAQAFSVFSQCRRMLTHTSNIKALTGFGTAAMADLFLKNKDEKNRAPYRVYTPPYVLAPVKEKAESGESFGQCSGEQCSVLYVSYCLSEDQRWLLAVATDERGEIFETATINIDIPNRIRRKKASARRIGLQKLMDFILGVMSQSVRPWRLVVGRIGRIGHGELKGWSWLLSRKSLLKASKHLKEICEQCSLMYPSDVPCVLSACLVSLEPDSALRLMPDQFTPDERFSQTSVNCQLSTPHDVSCTHILVFPTSATSQSSQTAFQEQHINGPDLGDDELFSALNDDMPEGIEGMQDFNDIFSWPETGPGGAQSPTGSPRRGDSPSQPGSPSCGVGGTSDQHSPFPCNGSSRGGGSVGVDTQEEVGTLHQQPLALGFFVSTAPTGRMPKWFWASCPHLENVCPAFLKNALHLHSPAIQQNSDDLLQQQSAVTVHALDSQYTTDVLRYVLEGYNALSWLALDSNTRDRLSCLPVHVQALMQLYHVTSALV |
Length | 489 |
Position | Middle |
Organism | Cryptotermes secundus |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Polyneoptera> Dictyoptera> Blattodea> Blattoidea> Termitoidae>
Kalotermitidae> Cryptotermitinae> Cryptotermes.
|
Aromaticity | 0.08 |
Grand average of hydropathy | -0.282 |
Instability index | 55.04 |
Isoelectric point | 5.97 |
Molecular weight | 53742.19 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364134
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP17802
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 40.12| 10| 111| 74| 85| 2
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74- 85 (16.75/14.07) CsgEQCSVLYVS
188- 197 (23.37/12.44) C..EQCSLMYPS
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 72.81| 21| 21| 418| 438| 3
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409- 424 (20.68/ 9.56) .....ALHLHSPAIQQNSDDL
425- 445 (34.87/20.48) LQQQSAVTVHALDSQYTTDVL
449- 462 (17.26/ 6.92) LEGYNALSWLALDS.......
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