<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17787

Description Uncharacterized protein
SequenceMMGFSYEKRALKRPRLGPPDVYPQEPKQKEDELTTLNVKHGFTTLPQLSDEFGTARNCNITASKVGAYFNAILTKKEELNTLPDTGRKRQQINPKDNFWPATARTKNAIEAWFKDLAGSKPLSSLSKKAPNFNKKEEIFIMLCEYQVPMLRAAWFIKLSYAYTVAVSEVKIKKRQLSDPSQEWTATLIKFLKDQLNRLQDFYHQSGGNVSGGTASTAANSSSVSTGVVNSSATGGNNAAGNGSSSNGSSTATPVASAGAASSTNTGVNTNAGSSSVQPTAGSTSVPAMTEDQKLAQRQWQFCVQLAKYLYEEGLLERQEFLQWILELLDKMRSSPSDDGILKLLLPLALQYLDEFVQSELLARKLAYLCAKKLAQLCSVATDTAVTNALSSSPALPPSASPQSPLLPGNIILPQSGPTQQTAPVNPLLVTFNEYMSCPHHRDIVLGLSAILQAVTLDCATALVWNCVGEGKSPSVLNGSSLDHLSCAPSTLPMPQRANNPAVRRQLRAAEEHIRNRSRAAEGRWSCDKWQQSSAGRTTSKVLTALDALDRHSFDRMDATNSLDTLYAKIFAPPGTKESSLAGSSCGNTNTTSNNGSNSTVSNSGTNGGDSSRENRADYTLLQDEAVVQILCEWAVSSQRSGEHRAMAVAKLLEKRQSDLMSGEADAADEKDSVSSANGAPTGVPVFQPLLMRFLDNDAPILEDNPTAQNRAMFTNLVHLFSELIRHDIFSHDVYMCTLISRGDLNTGGPAAVASHHPTSNKPATPAESRGPVNNSGIQDDDGSLFPGIDLKPTKLDVQDHGRNMDYDDSKIDDDLDKLLQHIKEEQQNSLDAPDSPKDDGVPPGSLVAAPMASVTPMEGAESGGPGEMRSRHLLYTTHFPLPHDEPGSLHDCNQRHVLLYGVGRVRDEARHTIKKMTKEICKLFSKKFSIDVAEGGKVKKHSRGEFNFEATTAKMQALSYFDQHVVTWQCTVTVVEMLNSFASGSSNYLPVQEHVAFLFDLMELAFSIYDLIDVCIQILKELPEVEGQLQAKGSGLVRSYTTSLSLYVVGVLRRYHCCLLLFPEQTTAVFEGLCRVVKHVTNPGDCSSAERCILAHLYDLYSSCSLLKSKPHCVEPFGNAYPKIRQALYSTVQPSSSNHVCNAQFMADVFSNPRRGGRIEPHWARQLAETPNNRYSFVCNAVVAVCNETDNDRLNDLAILCAELTACCNSLSAEWLGVLMALCCSSNHSSHFIDVLAQVDVQDLSIHNSLAVFTSILIARHCFSLEDFVVHIALPSLVKACNEGRGDADIEAEAGARLTCHLLLRLFKTVECPQPALYSVGTSPHPIPCATSNLGYSIKLSCDRHLLAAAHNNIRVGPVLAVLKEWDKP
Length1369
PositionKinase
OrganismCryptotermes secundus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Polyneoptera> Dictyoptera> Blattodea> Blattoidea> Termitoidae> Kalotermitidae> Cryptotermitinae> Cryptotermes.
Aromaticity0.07
Grand average of hydropathy-0.274
Instability index45.01
Isoelectric point6.17
Molecular weight149184.01
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17787
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     247.76|      69|     155|     172|     253|       1
---------------------------------------------------------------------------
  182-  243 (97.40/63.79)	...................EWTATLIKFLKDQLNRLQDFYHQSGGNVSGGTASTAANSSSV.....STGVVNSSATGGNNAAGNGS
  244-  275 (39.37/21.30)	SSNGSST......................................................atpvaSAGAASSTNTGVNTNAGSSS
  582-  611 (36.88/12.28)	............................................GSSCGNT.NTTSNNGSN.....ST.VSNS...G..TNGGDSS
  613-  682 (74.11/38.73)	ENRADYTllqdeavvqilcEWAVSSQRSGEHRAMAVAKLLEKRQSDLMSGEADAADEKDSV.....SS..ANGAPTG.........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.75|      14|      15|     344|     357|       2
---------------------------------------------------------------------------
  320-  333 (23.43/15.17)	FLQWILELLDKMRS
  344-  357 (23.31/15.05)	LLPLALQYLDEFVQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.00|      24|      36|    1118|    1152|       3
---------------------------------------------------------------------------
 1118- 1143 (39.98/32.78)	GNAYPKIRQALYSTvqPSSS.NHVCNA
 1157- 1181 (42.02/14.44)	GRIEPHWARQLAET..PNNRySFVCNA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.58|      13|      15|     397|     411|       4
---------------------------------------------------------------------------
  397-  409 (24.19/14.94)	PSASPQSPLLPGN
  413-  425 (24.38/ 8.48)	PQSGPTQQTAPVN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      62.59|      13|      15|    1207|    1219|       5
---------------------------------------------------------------------------
 1207- 1219 (24.60/15.03)	CCNSLSAEWLGVL
 1224- 1236 (20.62/11.29)	CSSNHSSHFIDVL
 1246- 1257 (17.37/ 8.22)	IHNSL.AVFTSIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.02|      27|      40|    1006|    1038|       6
---------------------------------------------------------------------------
 1006- 1038 (34.14/44.22)	FSIYdLIDV.....CIQILkeLPEvegQLQAKGSGLVR
 1044- 1075 (44.88/31.58)	LSLY.VVGVlrryhCCLLL..FPE...QTTAVFEGLCR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.10|      35|      43|      29|      69|       7
---------------------------------------------------------------------------
   29-   69 (47.47/44.74)	KEDELTTLNvKHGfTTLPQLS..DEF..GTARncniTASKVGAYF
   75-  113 (53.63/30.36)	KKEELNTLP.DTG.RKRQQINpkDNFwpATAR....TKNAIEAWF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.95|      19|     155|     825|     848|      10
---------------------------------------------------------------------------
  825-  846 (29.86/22.69)	EQQNSLDAPDS..............PKDDgvpPGSL
  857-  889 (27.08/ 7.84)	MEGAESGGPGEmrsrhllytthfplPHDE...PGSL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17787 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ESSLAGSSCGNTNTTSNNGSNSTVSNSGTNGGDSSRENRAD
2) NTGGPAAVASHHPTSNKPATPAESRGPVNNSGIQDDDGSLFPGIDLKPTKLDVQDHGRNMDYDDSKIDDDLDKLLQHIKEEQQNSLDAPDSPKDDGVPPGSLVAAPMASVTPMEGAESGGPGEMRSRHLLYTT
3) TGVVNSSATGGNNAAGNGSSSNGSSTATPVASAGAASSTNTGVNTNAGSSSVQPTAGSTSVPAMT
577
745
225
617
877
289










Molecular Recognition Features






MoRF SequenceStartStop




1) MMGFSYEKRALKRPRLGPPDVYP
1
23