<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17784

Description Uncharacterized protein (Fragment)
SequenceMMGFSYEKRALKRPRLGPPDVYPQEPKQKEDELTTLNVKHGFTTLPQLSDEFGTARNCNITASKVGAYFNAILTKKEELNTLPDTGRKRQQINPKDNFWPATARTKNAIEAWFKDLAGSKPLSSLSKKAPNFNKKEEIFIMLCEYQVPMLRAAWFIKLSYAYTVAVSEVKIKKRQLSDPSQEWTATLIKFLKDQLNRLQDFYHQSGGNVSGGTASTAANSSSVSTGVVNSSATGGNNAAGNGSSSNGSSTATPVASAGAASSTNTGVNTNAGSSSVQPTAGSTSVPAMTEDQKLAQRQWQFCVQLAKYLYEEGLLERQEFLQWILELLDKMRSSPSDDGILKLLLPLALQYLDEFVQSELLARKLAYLCAKKLAQLCSVATDTAVTNALSSSPALPPSASPQSPLLPGNIILPQSGPTQQTAPVNPLLVTFNEYMSCPHHRDIVLGLSAILQAVTLDCATALVWNCVGEGKSPSVLNGSSLDHLSCAPSTLPMPQRANNPAVRRQLRAAEEHIRNRSRAAEGRWSCDKWQQSSAGRTTSKVLTALDALDRHSFDRMDATNSLDTLYAKIFAPPGTKESSLAGSSCGNTNTTSNNGSNSTVSNSGTNGGDSSRENRADYTLLQDEAVVQILCEWAVSSQRSGEHRAMAVAKLLEKRQSDLMSGEADAADEKDSVSSANGAPTGVPVFQPLLMRFLDNDAPILEDNPTAQNRAMFTNLVHLFSELIRHDIFSHDVYMCTLISRGDLNTGGPAAVASHHPTSNKPATPAESRGPVNNSGIQDDDGSLFPGIDLKPTKLDVQDHGRNMDYDDSKIDDDLDKLLQHIKEEQQNSLDAPDSPKDDGVPPGSLVAAPMASVTPMEGAESGGPGEMRSRHLLYTTHFPLPHDEPGSLHDCNQRHVLLYGVGRVRDEARHTIKKMTKEICKLFSKKFSIDVAEGGKVKKHSRGEFNFEATTAKMQALSYFDQHVVTWQCTVTVVEMLNSFASGSSNYLPVQEHVAFLFDLMELAFSIYDLIDVCIQILKELPEVEGQLQAKGSGLVRSYTTSLSLYVVGVLRRYHCCLLLFPEQTTAVFEGLCRVVKHVTNPGDCSSAERCILAHLYDLYSSCSLLKSKPHCVEPFGNAYPKIRQALYSTVQPSSSNHVCNAQFMADVFSNPRRGGRIEPHWARQLAETPNNRYSFVCNAVVAVCNETDNDRLNDLAILCAELTACCNSLSAEWLGVLMALCCSSNHSSHFIDVLAQVDVQDLSIHNSLAVFTSILIARHCFSLEDFVVHIALPSLVKACNEGRGDADIEAEAGARLTCHLLLRLFKTVECPQPALYSVGTSPHPIPCATSNLGYSIKLSCDRHLLAAAHNNIRVGPVLAVLKAILVVGDATAREGKTPSSKSKPEQSQQMHSSGAAGGSNKTPISGSSGGELSISHILGTSDILSGGEDPLLDLGVVDAEPATRTGQR
Length1450
PositionKinase
OrganismCryptotermes secundus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Polyneoptera> Dictyoptera> Blattodea> Blattoidea> Termitoidae> Kalotermitidae> Cryptotermitinae> Cryptotermes.
Aromaticity0.06
Grand average of hydropathy-0.275
Instability index45.98
Isoelectric point6.13
Molecular weight157067.56
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17784
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     247.76|      69|     155|     172|     253|       1
---------------------------------------------------------------------------
  182-  243 (97.40/61.06)	...................EWTATLIKFLKDQLNRLQDFYHQSGGNVSGGTASTAANSSSV.....STGVVNSSATGGNNAAGNGS
  244-  275 (39.37/20.27)	SSNGSST......................................................atpvaSAGAASSTNTGVNTNAGSSS
  582-  611 (36.88/11.61)	............................................GSSCGNT.NTTSNNGSN.....ST.VSNS...G..TNGGDSS
  613-  682 (74.11/37.00)	ENRADYTllqdeavvqilcEWAVSSQRSGEHRAMAVAKLLEKRQSDLMSGEADAADEKDSV.....SS..ANGAPTG.........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.75|      14|      15|     344|     357|       2
---------------------------------------------------------------------------
  320-  333 (23.43/14.53)	FLQWILELLDKMRS
  344-  357 (23.31/14.42)	LLPLALQYLDEFVQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.00|      24|      36|    1118|    1152|       3
---------------------------------------------------------------------------
 1118- 1143 (39.98/38.97)	GNAYPKIRQALYSTvqPSSS.NHVCNA
 1157- 1181 (42.02/17.30)	GRIEPHWARQLAET..PNNRySFVCNA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.58|      13|      15|     397|     411|       4
---------------------------------------------------------------------------
  397-  409 (24.19/16.45)	PSASPQSPLLPGN
  413-  425 (24.38/ 9.27)	PQSGPTQQTAPVN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      62.59|      13|      15|    1207|    1219|       5
---------------------------------------------------------------------------
 1207- 1219 (24.60/14.13)	CCNSLSAEWLGVL
 1224- 1236 (20.62/10.61)	CSSNHSSHFIDVL
 1246- 1257 (17.37/ 7.72)	IHNSL.AVFTSIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.02|      27|      40|    1006|    1038|       6
---------------------------------------------------------------------------
 1006- 1038 (34.14/32.98)	FSIYdLIDV.....CIQILkeLPEvegQLQAKGSGLVR
 1044- 1075 (44.88/23.50)	LSLY.VVGVlrryhCCLLL..FPE...QTTAVFEGLCR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.10|      35|      43|      29|      69|       7
---------------------------------------------------------------------------
   29-   69 (47.47/42.78)	KEDELTTLNvKHGfTTLPQLS..DEF..GTARncniTASKVGAYF
   75-  113 (53.63/28.96)	KKEELNTLP.DTG.RKRQQINpkDNFwpATAR....TKNAIEAWF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.44|      34|     267|     539|     574|      10
---------------------------------------------------------------------------
  539-  574 (54.26/50.11)	SKVLTALDALDRHSfdRMDATNSLDTLYAKI..FAPPG
  809-  844 (56.19/43.33)	SKIDDDLDKLLQHI..KEEQQNSLDAPDSPKddGVPPG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.73|      19|      23|     856|     874|      13
---------------------------------------------------------------------------
  856-  874 (35.69/22.93)	PMEGAESGGPGEMRSRHLL
  880-  898 (36.04/23.24)	PLPHDEPGSLHDCNQRHVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.25|      29|     910|     440|     474|      14
---------------------------------------------------------------------------
  440-  474 (45.40/41.96)	HRDIVLG.LSAILQAV.TLDCATAlvwncvGEGKSPS
 1351- 1381 (41.85/24.31)	HNNIRVGpVLAVLKAIlVVGDATA......REGKTPS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17784 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AREGKTPSSKSKPEQSQQMHSSGAAGGSNKTPISGSSGGE
2) ESSLAGSSCGNTNTTSNNGSNSTVSNSGTNGGDSSRENRAD
3) NTGGPAAVASHHPTSNKPATPAESRGPVNNSGIQDDDGSLFPGIDLKPTKLDVQDHGRNMDYDDSKIDDDLDKLLQHIKEEQQNSLDAPDSPKDDGVPPGSLVAAPMASVTPMEGAESGGPGEMRSRHLLYTT
4) TGVVNSSATGGNNAAGNGSSSNGSSTATPVASAGAASSTNTGVNTNAGSSSVQPTAGSTSVPAMT
1374
577
745
225
1413
617
877
289










Molecular Recognition Features






MoRF SequenceStartStop




1) MMGFSYEKRALKRPRLGPPDVYP
1
23