<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17780
Description |
Mediator of RNA polymerase II transcription subunit 15 |
Sequence | MAAEDSSWRTATFRQSVVVKIDEAIRTSGMPTSKNSMEMENHVFQKAKSKEEYLGFVARLILHVREMNAKKGPGIGVPGGGTGGQAAQDPIGALQNLARQGTGNQIMGLGPQGGGMVQPSSIPASSLLQTLNQRPQGLSGMQPMQDKIPPGIGMGPGPQVGPMVGMPGQMQSGPLPNVSCPSQMPGQIPTQMRVQLPAQMGGQLQGQIQGQSLGQMPQMAGQMPGQMSHMTQMQQPRKGGEGIMMTGQNAGFAGPRNVASSAFLRRSPSPSALQASPAGLGAAPASNQMAASPALAPSPSSQLTPMSTAQRSGGMAPSPSSSLNTPGPAVPTPSPCSLQEDQAYREKVRQLSKYIEPLRRMINRMGNDG |
Length | 369 |
Position | Tail |
Organism | Cryptotermes secundus |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Polyneoptera> Dictyoptera> Blattodea> Blattoidea> Termitoidae>
Kalotermitidae> Cryptotermitinae> Cryptotermes.
|
Aromaticity | 0.02 |
Grand average of hydropathy | -0.460 |
Instability index | 66.95 |
Isoelectric point | 10.23 |
Molecular weight | 38411.62 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364148
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GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
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GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
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GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP17780
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 53.74| 17| 27| 102| 123| 2
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102- 123 (28.30/17.58) TGNQimglGPQG.GGMvQP..SSIP
130- 149 (25.44/ 6.07) TLNQ....RPQGlSGM.QPmqDKIP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 48.87| 14| 18| 292| 305| 4
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292- 305 (27.68/11.56) SPALAPSPSSQL.TP
312- 326 (21.19/ 6.93) SGGMAPSPSSSLnTP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 123.18| 27| 27| 199| 225| 5
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199- 225 (50.53/23.32) QMG..GQLQGQIQGQSLGQMPQMAGQMP..G
226- 251 (38.13/15.41) QMShmTQMQQPRKG...GEGIMMTGQNA..G
259- 287 (34.53/13.11) ASS..AFLRRSPSPSALQASPAGLGAAPasN
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