<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17760

Description Mediator of RNA polymerase II transcription subunit 28
SequenceMAATTNGNGNLVDEFEEAFQSCLSVLTKEEVLPTMEKDEIRVEVDHTILRFIDLARQMEAFFLQKRFLLSALKPELVVKEDTNELRQELVRKEELIKRHYEKIAVWQNLFADLQGWAKSPAQGPASSGLPNGNSGPQPPAPPTGAPPQPNMSSNMQQQLQQQQLQQQQIQQQQQQQLQQQIQQQQMQQQIQQQQMQQQGPPGISVASGSGGPGPMVSPQQAMFLQQSAGPRGAPGFPTQGPGGVLQGPLAFLEKTTSNIGMPEGRR
Length266
PositionHead
OrganismCryptotermes secundus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Polyneoptera> Dictyoptera> Blattodea> Blattoidea> Termitoidae> Kalotermitidae> Cryptotermitinae> Cryptotermes.
Aromaticity0.05
Grand average of hydropathy-0.698
Instability index74.85
Isoelectric point5.33
Molecular weight29396.85
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17760
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      84.26|      15|      15|     165|     179|       1
---------------------------------------------------------------------------
  165-  179 (30.46/ 9.76)	QQQQIQQQ.QQQQLQQ
  182-  197 (27.41/ 8.09)	QQQQMQQQiQQQQMQQ
  212-  226 (26.39/ 7.53)	PGPMVSPQ.QAMFLQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.60|      22|     114|     111|     132|       4
---------------------------------------------------------------------------
  111-  132 (42.66/20.68)	ADLQGWAKSPAQGP...............ASSGLPNG
  228-  264 (34.94/15.69)	AGPRGAPGFPTQGPggvlqgplaflekttSNIGMPEG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.63|      32|      34|      26|      59|       5
---------------------------------------------------------------------------
   26-   59 (44.54/37.47)	LTKEEVLPTMeKDEIRVEVDHTILRfIDLARQME
   63-   94 (51.10/32.79)	LQKRFLLSAL.KPELVVKEDTNELR.QELVRKEE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17760 with Med28 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) WAKSPAQGPASSGLPNGNSGPQPPAPPTGAPPQPNMSSNMQQQLQQQQLQQQQIQQQQQQQLQQQIQQQQMQQQIQQQQMQQQGPPGISVASGSGGPGPMVSPQQAMFLQQSAGPRGAPGFPTQGPGGVLQGPLAFLEKTTSNIGMPEGRR
116
266










Molecular Recognition Features






MoRF SequenceStartStop




1) LAFLEK
249
254