<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17680

Description Uncharacterized protein
SequenceMGRSGIVLAIVLIGCLSAISIAKEEANKLGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVAFTDSERLIGEAAKNQAPINAERTIFDVKRLIGRKFEDKEVQRDMKLVPYKLVNKDGKPYIQVKLSGGETKVFSPEEISAMILTKMKETAEAFLGKKIKDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSILTIDNGVFEVLSTNGDTHLGGEDFDQRIMEYFIKLIKKKHGKDISKDNRALGKLRREAERAKRALSSQHQVRVEIESLFDGVDFSEPLTRARFEELNNDLFRKTMGPVKKAMDDAGLQKSQIDEIVLVGGSTRIPKVQQLLKDYFDGKEPNKGVNPDEAVAFGAAVQGGILSGEGGDETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTVVSIKVYEGERSMTKDCRLLGTFDLSGIPPAPRGTPQIEVTFEVDANGILNVKAEDKASGKSEKITITNEKGRLSQEEIERMVREAEEFAEEDKKVKEKIDARNALETYVYNMKNQIGDKDKLADKLESDEKEKIESATKEALEWLDENQSAEKEEYDEKLKEVEAVCNPIITAVYQRSGGAPGGGAESTEDDDEHDEL
Length661
PositionUnknown
OrganismLactuca sativa (Garden lettuce)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Cichorioideae> Cichorieae> Lactucinae> Lactuca.
Aromaticity0.06
Grand average of hydropathy-0.434
Instability index31.01
Isoelectric point5.08
Molecular weight72614.49
Publications
PubMed=28401891

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
endoplasmic reticulum chaperone complex	GO:0034663	IBA:GO_Central
endoplasmic reticulum lumen	GO:0005788	IBA:GO_Central
membrane	GO:0016020	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
endoplasmic reticulum unfolded protein response	GO:0030968	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central
ubiquitin-dependent ERAD pathway	GO:0030433	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17680
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.38|      29|      32|     559|     590|       1
---------------------------------------------------------------------------
  559-  590 (44.07/40.93)	KEKIDA..RNALEtyvYNMKNQIGDKDKLADKLE
  594-  624 (44.32/31.42)	KEKIESatKEALE...WLDENQSAEKEEYDEKLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.30|      11|      26|     226|     236|       2
---------------------------------------------------------------------------
  226-  236 (20.46/10.14)	LGGGTFDVSIL
  254-  264 (21.85/11.25)	LGGEDFDQRIM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.01|      17|      21|      61|      78|       3
---------------------------------------------------------------------------
   61-   78 (27.81/26.05)	NR..ITPSWVAFtDSERLIG
   83-  101 (25.20/17.45)	NQapINAERTIF.DVKRLIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.14|      20|      26|       5|      24|       4
---------------------------------------------------------------------------
    5-   24 (31.61/22.91)	GIVLAIVLIGCLSAISIAKE
   30-   49 (35.53/26.69)	GTVIGIDLGTTYSCVGVYKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.66|      25|      28|     382|     406|       6
---------------------------------------------------------------------------
  382-  406 (42.72/24.49)	GKEPNKGVNPDEA.VAFGAAVQGGIL
  411-  436 (35.94/19.54)	GDETKDILLLDVApLTLGIETVGGVM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     113.42|      44|     193|     271|     317|       7
---------------------------------------------------------------------------
  271-  293 (26.58/10.34)	............................................................................................................................................................................IKKKHG.KD..ISKDNRALGKLR........REA
  294-  317 (12.20/11.28)	ERAKRAlSSQHQVRVEIESlfDGV......................................................................................................................................................................................
  466-  489 (21.05/ 6.67)	........................dfsepltrarfeelnndlfrktmgpvkkamddaglqksqideivlvggstripkvqqllkdyfdgkepnkgvnpdeavafgaavqggilsgeggdetkdillldvapltlgietvggvmtkliprntviptkksqvfttyqdqqtvvsIKVYEGeRS..MTKDCRLLGTFD........LSG
  491-  548 (53.60/29.06)	PPAPRG.TPQIEVTFEVDA..NGI...............................................................................................................................................lnvkaEDKASG.KSekITITNEK.GRLSqeeiermvREA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17680 with Med37 domain of Kingdom Viridiplantae
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