<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17646

Description Uncharacterized protein
SequenceMMNSGSTGSERAADLYNEPDMDIETWVNELYTDEFRDSLMNLGFDDIIINPDYASDQPNMSVNSRSIFGGGSADKSQRGIPEERMTVSSLTPNSSTPTLQTSGHILSPLPTFVSNPASQSSPSHTTQDLPQFTNQNQPLKQQIFEHTAVQQPPTHPSMTQSTIMFGQQKTNQQMASDHLRPCPRPVSTIKKIHLQNLQTPMQQISNTSQVQKRQKQMVVHPLQNFQQNQNQTQQPAVMTPHILMPEGGQHRVHGLLIGSEGQKKPQGHISTALPATAGFSHPNEFSTNENWRECAFRQETNVEIATKYGHAKVFLEKMINFLNIATIDKIPKNRERVYNYMNFIINYLTSFRIKNGGSSPIFDQMINQAPEDHSQSKGSYLQPSGGDMRLPYNLQENLNHGVINLEQNILNFNQQRLHQPVDIQKGNGDMRLQNMPPPNSSQGINLATREAEMMKFNQYFPSRRPEGRITSTLISNDSYQMGSVNPLLTGSFKSTQPTVLGTTQRSNLGPRPSSVNVSTSSMSLLRAATAANFPSRQVNHQPSLVNQSFNSEKMKQPMQKSNHEMITGSNQGQVLSPLAALLQNQFPSQPAPNPIILQPSGQHSVSSWQVNANNVLSPQSIACSPFLLGSSSAPSRREKHHSSSGPASVSNTEGQRQEIPIIAGMFKNQKTMNNKVSDMDHPKTPTASPPMDTTPCTEKAAVSEDSKDPVVHLTETVESLPSKTVGSSMNDITIVEQDHHSVPAYPEPAKPVGGNTEPIFDEELVNLDHLNIGEETAFLFAPENVPQQKVKRKFTSASHSSQDFGDFDSIDQFFSEEWDSDSTVPSMKKKSKIECTNLAISEEIKEINKKLLETSSEMVANYPVEDSNSILEGHEGIKVTLVYRNVCIPDLFRNQAGVTSKMRPEFRIKLLVPLNYPASSPTILKGSHDNVSSEPWPQLYEEMVSKFHCAIRELPEPMSLGDMARKWDACARSVITDFVQGIGGKSFSIKYGSWESSSVSK
Length1001
PositionTail
OrganismLactuca sativa (Garden lettuce)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Cichorioideae> Cichorieae> Lactucinae> Lactuca.
Aromaticity0.06
Grand average of hydropathy-0.638
Instability index57.61
Isoelectric point6.22
Molecular weight111095.26
Publications
PubMed=28401891

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IBA:GO_Central
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17646
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     626.55|     136|     136|     384|     519|       1
---------------------------------------------------------------------------
   77-  152 (46.37/17.27)	.......................................................QRGIPEERMTvS.SLTP.....NSST........................PT...LQTSGHILSplpTFVSNPASQSSPSHttqdlpqftnqnqPLKQQIFEHT.......AVQQ.......P.........
  156-  291 (159.81/79.10)	.......PSMTQ..STIMFGQQKTNQ..QMAS..D........HLRPCPRPVS.TIK...KIHLQ.N.LQTPmqqisNTSQ...VQKRQKQMVvhplqNF.QQNQNQ...TQQPAVMTP...HILMPEGGQH.RVH.............GLLIGSEGQKKPQgHISTALPATAGfshPNEFSTNENW
  292-  382 (58.95/24.12)	RECAFRQETNVEiaTKYGHAKVFLEKmiNFLN..IatidkipkNRERVYNYMNfIINYLTSFRIK.NgGSSP.....IFDQMINQAPEDHSQS.....K..GSYLQ.................................................................................
  384-  519 (231.04/117.92)	SGGDMRLPYNLQ..ENLNHGVINLEQ..NILN..F........NQQRLHQPVD.IQKGNGDMRLQ.N.MPPP.....NSSQGINLATREAEMM.....KF.NQYFPS...RRPEGRITS...TLISNDSYQMGSVN.............PLLTGSFKSTQPT.VLGTTQRSNLG...PRPSSVNVST
  528-  649 (130.38/63.05)	ATA...........ANFPSRQVNHQP..SLVNqsF........NSEKMKQP...MQKSNHEM........IT.....GSNQGQVLSPLAALLQ....nQFpSQPAPNpiiLQPSGQ........HSVSSWQVNANN...vlspqsiacsPFLLGS..SSAP....SRREKHHSS...SGPASV....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     183.33|      57|     172|     743|     822|       2
---------------------------------------------------------------------------
  758-  822 (91.55/83.69)	PIFDEELVNLDHLNIGEetaflfAPENVPQQKVKRKFTSASHSS.QDFgdFDSI.DQFFSEE...WDSDS
  937-  998 (91.78/43.07)	PQLYEEMVSKFHCAIRE......LPEPMSLGDMARKWDACARSViTDF..VQGIgGKSFSIKygsWESSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      86.47|      21|     136|     696|     721|       3
---------------------------------------------------------------------------
  696-  716 (34.24/16.75)	CTEKAAVSEDSKDPVVHLTET
  835-  854 (31.73/14.58)	CT.NLAISEEIKEINKKLLET
  864-  881 (20.51/18.40)	VEDSNSILEGHEGIKVTL...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.36|      19|      60|     672|     690|       4
---------------------------------------------------------------------------
  672-  690 (36.99/18.16)	MNN.KVSDMDH...PKTPTASPP
  729-  751 (27.37/11.67)	MNDiTIVEQDHhsvPAYPEPAKP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17646 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ATAANFPSRQVNHQPSLVNQSFNSEKMKQPMQKSNHEMITGSNQGQV
2) FLLGSSSAPSRREKHHSSSGPASVSNTEGQRQEIPIIAGMFKNQKTMNNKVSDMDHPKTPTASPPMDTTPCTEKAAVSEDSKDPVVHLTETVESLPSKTVGSSMNDITIVEQDHHSVPAYPEPAKPVGGNTEPIFDEELVN
3) GSFKSTQPTVLGTTQRSNLGPRPSSVNVSTSS
4) PNMSVNSRSIFGGGSADKSQRGIPEERMTVSSLTPNSSTPTLQTSGHILSPLPTFVSNPASQSSPSHTTQDLPQFTNQNQPLKQQIFEHTAVQQPPTHPSMTQSTIMFGQQKTNQQMASDHLRPCPRPVSTIKKIHLQNLQTPMQQISNTSQVQKRQKQMVVHPLQNFQQNQNQTQQPAVMTPHILMP
5) RLHQPVDIQKGNGDMRLQNMPPPNSSQGINLAT
528
626
490
58
416
574
766
521
245
448










Molecular Recognition Features






MoRF SequenceStartStop




1) AADLY
2) IKKIHL
12
189
16
194