<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17637

Description Uncharacterized protein
SequenceMQRYHATNCTSAVNNSAVGGSLGRDNTSRAESSSLPANFPLNRRTSQLAPYKLRCEKEPLNSRLPPPDFHPPTANCPEETLTKDYVLGGYRETVEGLEESREISLSQIPTFTKPVILKCKEAIRKYHRAINESRAQKRKAGQVYGVPLTGNLLSKPGFFPEQKASGEDFRKKWIEGLSQQHKRLRSLADHVPHGYRRKSLFEVLIRNNVPLLRATWFIKVTYLNQVRPGSGTSSGSPDKTRFLRSDQWTKDIIEYLQYLLDEFVSKNNSHSTLHLKDRSPQFAYGGGVQHKNDVLAVVDGEEPSVHFKWWYVVRIIQWHHAEGLLLPSLIIDWVLNQLQEKESLGTLQLLLPIIYGVIETIILSQNYVRTLVAIAIRFIHEPSPGGSDLVENSRRAYTISALIEILRYLILAVPDTFVSLNCFPLPPSILSNPTTDNNSLITRVKPATSSELQGPFSSIDTLVYSIQKCAMNLARAARPGCPGHNVAKSVRELDKAVTHGDIGSAYKCLFEDFNDENVDRRWMADVSAGLQSSLKWVGTVNSAFVCSVFFVCEWATCDFRDSRNAPVEGVKFSGKRDFSQIYIATRILSMKMRNKRRKVKDLSRFFQSPGPLHDVIVCWLDQHQVQNGEGFKRVQLLITELTRSGIFYPQAYVRELIVSGIMGKNDNLLDIERKRRHYKLLKHLPGSYVQDSLEEAQVADVSLISEAMQIYTNERRLLLHENVISTNGKNNHKFGRIPSPKNVKIEEVMASISALLHFPNSNGNGIDDSHGVKRPVGPVVSEGPTPGCEECRRAKRQKVEEKSPFLHLSDDEDIWWVRKGGVTVKPMDSFRVDPPVKPIKQPTRGRQKIVRKTQSLAQLAAARIEGSQGASTSHVCDSRVNCPHHRNGTDVSKPPDSVGITNSAGIGNSRDISSIGKVIKRIPLDEKRVIVVWLMGIVKQLVEEAGKVTDSGPKSGQFGRNLPVVDDKGLGKWKLGEDELSNILYLMDVCDDLVSAARFLVWLLPKVHVNPIPTVHGGRNVMIVPRNVENQLCAVGEAYILSSLKRYENILAAADLIPETLTAMMHRASLVMSSNGRLSGSPSLIFSRQILKKYADVATVIDWSKTFKTTSDKRLIMELESGRSSDGEFGFPLGVPAGIQDFDEFLRQKITGIRISRVGLGMRDTVQRLIDENIPSFYGQDKKSTFPVKRPVDDGYPIAQQVVKGLLDCMRQTGGAAQEGDPTLVAFAVSAVVTNVGQVIGKITEITPASCLFARHILKIHLTILSLLKDALGERQSRVFEIALATEASSALSQVFTPPKASRGQLQLSPDTRDPGVNSSNEKTYSKPAKTTGAISALVIGAVLQGIASLERMVTVFRLKEGLNVIQFVRSTRSNSNGNVRSTPVNDSKIDNLVEVSVHWFRVLIGNTRTVSDGFIVELLGESSIIALTRIQRMLPVNLVFPPAFAIFGFLIWKRFILNPNVITRDNITQLFQSLTSGITDAIKHLPFRDVCLRECSTLYDLVASDPTDSEFAAFLDSNAPKVSAFVPLRARVFLNSIIDCQLPPELVNPEDGNRVSGHSESLLEKLVHILDTLQPAKFHWQWVELRLLLNEQALIEKMEGRDASLVEALSSFSPDGTSENENNFIQMVLTRLLVRPDAAPLFSEVVHLLGRSLEDEVLLQAKWFLRGHDVLFGRKSIRQRLINIADSKGLSTKPQFSKPWGWCSGSNSIPGLKKGNQKRKFEVVEEGEVVEDGNGIETKRNTNIEAFVVTQQNVTERALVELLLPCIDESSEDSRVTFAGDLIKQMNEIEQQISGVTNGANKQAGMAVSGAEGPVSKANTRKGIRGGSPGLARRNPPPVEVILPSPSALRSSMSLRLQLLLRLLPVICADGEPSSRSMRHMLASVVLRLLGSRVVHEDADLSSPASRFSIKREVESMIESSGTVDLGGSLFDRLLLVLHALLSGCQPHWMKPKTLSKSTIEATTTTSLYDRDAAESLQNELDNMQLPEAVRWRIQTAMPFVFPSLKFTISCQPPNIPLSAVTSLQPPVPVPASGTIRNMPSRATSNGPTKPTKPIPPPTHVSSIPSSQPDPDTEIDPWTLLEDGAGSGPSSINGSAIAGTDHANLKASTWLKGAVRVRRMDLTYIGAIDDDS
Length2133
PositionKinase
OrganismLactuca sativa (Garden lettuce)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Cichorioideae> Cichorieae> Lactucinae> Lactuca.
Aromaticity0.06
Grand average of hydropathy-0.233
Instability index48.93
Isoelectric point8.99
Molecular weight235955.46
Publications
PubMed=28401891

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17637
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     207.56|      39|     510|    1143|    1206|       1
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  759-  788 (46.22/35.26)	........PNSN..GNGID..DSHGVKRPV..GPVVSEGPTPGC
  811-  845 (36.91/ 8.05)	....DEDIWWVRkgGVTVKpmDSFRVDPPVK...PI.KQPTRG.
 1167- 1206 (64.71/24.13)	QRLIDENIPSFY..GQDKK..STFPVKRPVDdGYPIAQQVVKGL
 1680- 1713 (59.72/18.06)	QRLI..NIADSK..GLSTK..PQFS..KPW..GWCSGSNSIPGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     426.31|     141|     363|     238|     403|       2
---------------------------------------------------------------------------
  238-  403 (205.61/170.43)	DKTRFLRSDQWTKDIIeyLQYLLDEFVSKNNSHSTLHL....KDRS....PQfAY.....GGGVQHKNDVLavVDGEEPSVHFkwwyvvriiqwhhaEglLLPSLIIDWVLNQLQEKEsLGTLQLLLPI..IYGVIETIILSQNYVRTLVAIAIRFIHEPSPGGsdlVENSRRAYTISALI
  601-  756 (220.69/125.34)	DLSRFFQSPGPLHDVI..VCWLDQHQVQNGEGFKRVQLliteLTRSgifyPQ.AYvreliVSGIMGKNDNL..LDIERKRRHY..............K..LLKHLPGSYVQDSLEEAQ.VADVSLISEAmqIYTNERRLLLHENVISTNGKNNHKFGRIPSPKN...VKIEEVMASISALL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     140.95|      45|     477|    1499|    1547|       3
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 1499- 1547 (69.60/49.89)	LYDLVASDPTDSEFAAFLDSNAP..KVSAFVPLrarVF..LNSIIDCQlPPEL
 1969- 2017 (71.35/40.17)	LYDRDAAESLQNELDNMQLPEAVrwRIQTAMPF...VFpsLKFTISCQ.PPNI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     129.66|      40|     219|    1804|    1846|       4
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 1804- 1846 (61.82/43.96)	QAGMAVSgAEGPVSKANTRKGIRGGS.PglARRNPPPVEV.ILPS
 2026- 2067 (67.83/37.73)	QPPVPVP.ASGTIRNMPSRATSNGPTkP..TKPIPPPTHVsSIPS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     160.95|      51|     362|     486|     543|       5
---------------------------------------------------------------------------
  486-  543 (78.90/64.91)	VAK..SVRELDKAVTHGDIG..SAYKClfeDFNDENVDRRWMADVSAGLQSslkwVGTVNSA
  850-  904 (82.05/49.71)	VRKtqSLAQLAAARIEGSQGasTSHVC...DSRVNCPHHRNGTDVSKPPDS....VGITNSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.69|      33|     477|      94|     130|       6
---------------------------------------------------------------------------
   94-  130 (47.51/47.90)	VEGLEESREISLSQIPTFTKpvILKCKeaIRKYHRAI
  567-  599 (57.18/41.60)	VEGVKFSGKRDFSQIYIATR..ILSMK..MRNKRRKV
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17637 with Med12 domain of Kingdom Viridiplantae
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