<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17626

Description Uncharacterized protein
SequenceMSSRNGGGDSIGFDKAMRHNWSQHAKYLSQDKILKSNFLISLSTQKLSVEEIKAATARSFSCKVQNVTKAHNSQAEKAWQALSNLKLSSRSYIKPGKSRKVEKNGYSASFQDDKRASQQCSSDGNNKFTAQTWEDQNSNENNVEHIKPDQTTNLSTTVTTSVTETKRAETIQNGGYESDSTSVCRNDISGINRNHAKNWYHLHGLQEIDDEETYQNLDVDQTLTEHFQSSCTIQQSISSSPPFTPAANNSIVACEDISLPPELDVDCGHGFKACIQLPKLFQLGTCPEAATHLQDMKDMLISISNDLIDNDSELNSDELEKLRHDRLQLKKQIQQLKQYCSSILMDDEGCKTNFSAFTTARDLKYQTPLAFTSRVDPVRLDDQFYMHNKWDPPSISCSSVGNFGNFSTPVERELYVRKNVKVNYIDGSDDKKWSKKDFSWTKKLEANNKKVFGNHSFRPNQREVINATMSGNDVFVLMPTGGGKSLTYQLPALICPGVTLVISPLVSLIQDQIMHLLQANIPAAYLSSNMEWTKQQDILRDLCSGHCSYKLLYVTPEKVAKSDALLRQLENLYARELLDRIVIDEAHCVSQWGHDFRPDYQSLGILKQKFPNIPLLALTATATASVKEDVVQALGLVDCIIFRQSFNRPNLRFSVIPKTKKCMEDIDTFIKDNHFDECGIIYCLSRNDCEKVAKKLQEFGHKAAFYHASMDPDERASVQKMWSKDEVNIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQHSSCILYYSYSDYIRVKHMLSHGSIEQSSFASRSTTLNSGRVLETNTENLLRMVSYCENEVDCRRFLQLVHFGEKFDPLSCKKTCDNCSKTHTLVDKDVTQIAKHLVELVKSVRQEFSGTYVLEVYRGSMNQIVKKNQHDTLKLHGAGKNVAKGDASRVLRHLVIEEILLEDIKKSDLYGSVSSILKVNEKKACNLLEGQKTIMLRFPSVVRVSKSTTTTPAKGFLTSSKQTPSRVDTPAPAQSQPEVDSNLSTKLYGALRELRTLLVKEAAEGVMAYHIFGNATLKSISRRVPRTKEELLEINGIGKAKVSKYGDRVLETIEITLNEYISINVDSDSDSINFPKRGHDNDFTYKEPDSTNGLEIVDYPDDDQSTWRL
Length1150
PositionUnknown
OrganismLactuca sativa (Garden lettuce)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Cichorioideae> Cichorieae> Lactucinae> Lactuca.
Aromaticity0.07
Grand average of hydropathy-0.521
Instability index42.28
Isoelectric point7.04
Molecular weight129505.83
Publications
PubMed=28401891

Function

Annotated function 
GO - Cellular Component
chromosome	GO:0005694	IBA:GO_Central
cytoplasm	GO:0005737	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IBA:GO_Central
ATP binding	GO:0005524	IEA:UniProtKB-KW
four-way junction helicase activity	GO:0009378	IBA:GO_Central
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA duplex unwinding	GO:0032508	IBA:GO_Central
DNA recombination	GO:0006310	IBA:GO_Central
DNA repair	GO:0006281	IBA:GO_Central
DNA unwinding involved in DNA replication	GO:0006268	IBA:GO_Central
double-strand break repair via homologous recombination	GO:0000724	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17626
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     209.89|      72|     137|     905|     980|       2
---------------------------------------------------------------------------
  905-  980 (108.62/96.29)	IVKKNQHDTLKLHGAGKNVAKGDASRVLRhlVIEEIL.LEDIKKSDL..YGS..VSSI.LKVNEKKACNLLEGQKTImlRFP
 1039- 1116 (101.27/75.72)	LVKEAAEGVMAYHIFGNATLKSISRRVPR..TKEELLeINGIGKAKVskYGDrvLETIeITLNEYISINVDSDSDSI..NFP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     183.18|      57|      91|      49|     106|       3
---------------------------------------------------------------------------
   49-  106 (89.27/62.35)	VEEIKAATARSFSCKV.QNVTKAHNSQAEKAWQALSNLKLSSRSYIKpGKSRKVEKNGY
  143-  200 (93.91/60.62)	VEHIKPDQTTNLSTTVtTSVTETKRAETIQNGGYESDSTSVCRNDIS.GINRNHAKNWY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.35|      18|      97|     671|     700|       4
---------------------------------------------------------------------------
  682-  700 (29.65/37.36)	YCLSRNDCEKVAkKLQEFG
  828-  845 (35.70/13.80)	YCENEVDCRRFL.QLVHFG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.38|      13|     138|     445|     460|       7
---------------------------------------------------------------------------
  445-  457 (23.64/22.68)	EANNKKVFGNHSF
  463-  475 (22.74/ 9.93)	EVINATMSGNDVF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.65|      18|      18|     237|     254|       9
---------------------------------------------------------------------------
  237-  254 (32.18/23.90)	ISSSPPFTPAANNSIVAC
  257-  274 (34.47/26.23)	ISLPPELDVDCGHGFKAC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.69|      24|     455|     388|     413|      10
---------------------------------------------------------------------------
  388-  413 (41.37/32.70)	NKWDPpsISC.SSVGNFGNFSTPVERE
  846-  870 (41.32/25.33)	EKFDP..LSCkKTCDNCSKTHTLVDKD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17626 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KVEKNGYSASFQDDKRASQQCSSDGNNKFTAQTWEDQNSNENNVEHIKPDQTTNLSTTVTTSVTETKRAETIQNGGYESD
100
179










Molecular Recognition Features






MoRF SequenceStartStop




1) LEIVDYPDD
1135
1143