<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17621

Description Uncharacterized protein
SequenceMNIEGFTLLQFRFLVPPQQGQFRPMGQGMPPGQSQPPQFSQPHQQMSPWPRPSQPANATSSFIAPPMPYMQHPNMTCTSSSQNSATTNTHLPGLTGPGAPLSSSFTFITSSFGHPQNAMNASSNQQAMNVPNVFQEASSDWQEFIAADGRRYFYNKRTKMSSWEKPLELMTPVEKADSSTFWKEFTTAEGKRYYYNKETKQSKWTIPDELKMAREQAEKEASRSSQSLSSGSSVNDSCLTIPVVAVKPHSPVSPTVNDAPSVLVNTSSSPKTNLEITSSNDVANALDEASMQDIKEAKKDISDVGKVNVTLLEEKVMDAEPLLYANKKEAKLAFRSLLESANLEADWSWEQAMRVIINDKRYGALKTLGERKQAFNEYLVEKKKLEAEEKRLKLKKAKDEFMQMLEESKELTSSMRWSKAIALFEDDKRYKAIERPSEREDLFQDYLVDLKKKERAKLQEEKRQNRLEYRHFLETCGFIKVDTQWRKVKDWLEDDERCSRLEKIDRLEIFQEYIRELEKEDDEQRKLKKEEIKKMERKNRDEFSKMMEEHVVSGMLTVNTQWVDYFQKVKESEAYHAVASNTSGATAKDLFEDVAEELEKKYHDDKTRVKDALKIKKVSVAATWTFKDFKDAIQDDIISPPLSDINLQLVFEDLLKRAKEKEKKEHKRRRNLAKDFTQLLDNIKEINASSTWEDCKQLFEESNVYRSIGDEKFCQVAFEEYVARLVEKGTDNKHKQEDEKMKREKKEKGKDRERKHGQSPIDHRKSRKHVSHESDDESKHKRHKDDGEHVHDHEEELEDGEIC
Length803
PositionUnknown
OrganismLactuca sativa (Garden lettuce)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Cichorioideae> Cichorieae> Lactucinae> Lactuca.
Aromaticity0.08
Grand average of hydropathy-0.991
Instability index54.34
Isoelectric point6.22
Molecular weight93112.64
Publications
PubMed=28401891

Function

Annotated function 
GO - Cellular Component
U1 snRNP	GO:0005685	IBA:GO_Central
U2-type prespliceosome	GO:0071004	IBA:GO_Central

GO - Biological Function
RNA binding	GO:0003723	IBA:GO_Central

GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro
mRNA splicing, via spliceosome	GO:0000398	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17621
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     484.47|      66|      66|     319|     384|       1
---------------------------------------------------------------------------
  319-  384 (99.74/44.95)	AEPLLYANKKEAKLA..FRSLL.E....S.AN.LEADWSWEQAMRVIINDKRYGAL..KTLGER.K..Q.AFNEY...LVEKKK
  387-  452 (90.91/40.46)	AEEKRLKLKK.AKDE..FMQMLeE....S.KE.LTSSMRWSKAIALFEDDKRYKAI..ERPSER.E..D.LFQDY...LVDLKK
  454-  519 (86.29/38.11)	ERAKLQEEKRQNRLE..YRHFL.E....T.CGfIKVDTQWRKVKDWLEDDERCSRL..EKI.DR.L..E.IFQEY...IRELEK
  529-  597 (71.01/30.35)	KEEIKKMERKN.RDE..FSKMM.EehvvS.GM.LTVNTQWVDYFQKVKESEAYHAVasNTSGATaK..D.LFEDV......AEE
  598-  660 (75.37/32.56)	LEKKYHDDKTRVKDA..LK..I.K....K.VS.VAATWTFKDFKDAIQDDIISPPL..SDI.NL.Q..L.VFEDL...LKRAKE
  661-  728 (61.14/25.33)	KEK..KEHKRRRNLAkdFTQLL.D....NiKE.INASSTWEDCKQLFEESNVY.....RSIGDE.KfcQvAFEEYvarLVEK..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.64|      14|      17|      16|      31|       2
---------------------------------------------------------------------------
   16-   31 (27.86/21.26)	PPQQGQfrPMGQGMP.P
   36-   50 (27.78/14.41)	PPQFSQ..PHQQMSPwP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     155.00|      40|      40|     138|     177|       3
---------------------------------------------------------------------------
  138-  177 (77.80/50.39)	SSDWQEFIAADGRRYFYNKRTKMSSWEKPLELMTPVEKAD
  179-  218 (77.20/49.94)	STFWKEFTTAEGKRYYYNKETKQSKWTIPDELKMAREQAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      61.57|      14|      17|     763|     777|       4
---------------------------------------------------------------------------
  743-  753 (15.70/ 6.06)	REKKEK....GKDRE
  763-  777 (20.96/15.82)	HRKSRKHVsHESDDE
  783-  796 (24.91/14.02)	HKDDGEHV.HDHEEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.52|      14|      16|     242|     257|       5
---------------------------------------------------------------------------
  242-  257 (21.44/19.45)	PVVAVKPHSpvSPTVN
  260-  273 (25.07/14.89)	PSVLVNTSS..SPKTN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      65.51|      16|      16|      89|     104|       6
---------------------------------------------------------------------------
   73-   85 (16.22/ 7.01)	...PNMTC.TSSSQNSA
   89-  104 (27.69/16.53)	THLPGLTG.PGAPLSSS
  106-  122 (21.60/11.48)	TFITSSFGhPQNAMNAS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17621 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EKGTDNKHKQEDEKMKREKKEKGKDRERKHGQSPIDHRKSRKHVSHESDDESKHKRHKDDGEHVHDHEEELEDGEIC
2) PQQGQFRPMGQGMPPGQSQPPQFSQPHQQMSPWPRPSQPANATSSFIAPPMPYMQHPNMTCTSSSQNSATTNTHLPGLTG
727
17
803
96










Molecular Recognition Features






MoRF SequenceStartStop




1) IDHRKSRKHV
2) KHKRHK
761
779
770
784