<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17587

Description Uncharacterized protein
SequenceMDNNPQNSGAQSLRPPAIGSIGSQSFGTNFSIQFRPVVPSQQGQAHAFMQSGSGSQQYRPQFSQPRPGQPPSSQAMPMSSYMQQQPNMPMSSSSSSSSSSYTFTAPSFGTNVSSQFQMQTPVGGQPWPSSGNQGPLAVAPMPQTGHQPTNQQALNVLHSSSQEASSDWQEYTAGDGRRYYYNKNTKQSSWEKPLELMTPLERADASTVWKEFTTAEGKKYYYNKDTKQSKWTIPEELKLAREQAEKEASRSSQTEMVTNPNAPAISTPSALDQSSVNDISSTIPRVASSPAPHNVGSESSSVAIPLNPAVVAASMIPPNLHSSPMKMEDSSSHGVPKTLDGVSTHDTEEAKKGMAVAGKVNTTQIEEKVVDDEPFIYASKQEAKVAFKALLEDANVEADWNWEQAMRVIINDKRYGALKTLGERKQAFNEYLMQRKKLEAEERRLRQRKAKEEFTKMLEESKELTSSMRWSKAMAMFEDDERYKAVDRPSDREDLFQNYLVDLQKKERAKAQEEQRQYRSEYKQFLETCGLIKVDTQWRKVQDRLEDDERCSRLDKIDRLEIFQEYIRDLEKEEDEQRKIKKEHIKRVERKNRDEFRKMMEEDVNSGTLTAKTQWRDYCQKVKESVAYQAVASNTSGSTPKDLFEDVAEELEKKYHDDKTRVKDAMKLKKVSVVPTWTFEDFKAAIEDDIISSLSDINLQLVYEDVVERAKEKEEKEAKKRQRLTKEFTDLLYDIKDITASSTWEECQPLFEETSEYRGIGDEGVAREAFEEYVARLVDKAKERERKREEDKVRKEEKERRKEKERREKEKEKEKRLKKDKDDSDSENLDMMMEITTTTTKEDKKRDKKHRKRHHHQQQQQDDNDDDATSDKDEREDLDSSSKKSSSRRHGKKSRKHASAYSPESDSRDSESKHKKQKRDSRKNGNGGGEELEDGELGAGEDGEIQ
Length946
PositionUnknown
OrganismLactuca sativa (Garden lettuce)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Cichorioideae> Cichorieae> Lactucinae> Lactuca.
Aromaticity0.07
Grand average of hydropathy-1.212
Instability index56.23
Isoelectric point5.86
Molecular weight108485.85
Publications
PubMed=28401891

Function

Annotated function 
GO - Cellular Component
U1 snRNP	GO:0005685	IBA:GO_Central
U2-type prespliceosome	GO:0071004	IBA:GO_Central

GO - Biological Function
RNA binding	GO:0003723	IBA:GO_Central

GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro
mRNA splicing, via spliceosome	GO:0000398	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17587
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     169.42|      36|      38|     168|     205|       1
---------------------------------------------------------------------------
  168-  196 (49.07/26.70)	..........WQEYTA..GDGRRYYYNKNTKQSSWEKPLEL
  199-  237 (62.54/39.67)	PLERADAstvWKEFTT..AEGKKYYYNKDTKQSKWTIPEEL
  420-  443 (27.26/11.18)	..............TL..GE.RKQAFNEYLMQRKKLEAEER
  444-  472 (30.55/10.68)	RLRQRKA...KEEFTKmlEESKEL.....TSSMRWSK....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     131.31|      21|      30|      19|      41|       2
---------------------------------------------------------------------------
   19-   39 (40.84/18.49)	GSIGSQ.........SFGTNFSIQFRPVVP
   52-   70 (37.47/16.29)	GS.GSQ.........QYRPQFS.QPRPGQP
   73-   89 (24.92/10.06)	....SQ.........AMPMSSYMQQQPNMP
   92-  121 (28.07/ 9.46)	SSSSSSsssytftapSFGTNVSSQFQMQTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      88.88|      22|      22|     273|     294|       3
---------------------------------------------------------------------------
  273-  294 (38.16/24.08)	QSSV..NDISS.TIP....RVASSPAPHN
  295-  319 (25.69/13.83)	VGSE..SS.SV.AIPlnpaVVAASMIPPN
  322-  346 (25.03/13.29)	SSPMkmEDSSShGVP....KTLDGVSTHD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     335.19|      51|      56|     784|     834|       4
---------------------------------------------------------------------------
  508-  561 (37.50/12.24)	RAKAQEE.QRqYR.SEYK............................qfletcglikvdtQWR...KVQDRLE.DDERCSRL.DKiD...R...........LE
  568-  602 (48.58/17.88)	RDLEKEE.DE.QR.KIKK.........................................EHI...KRVER.............K.N...RD....EFRKMMEE
  651-  734 (34.92/10.93)	LEKKYHD.DK.TRvKDAMklkkvsvvptwtfedfkaaieddiisslsdinlqlvyedvvERA...KEKE..EKEAKKRQRL.TK...........EFTDLLYD
  740-  783 (26.37/ 6.58)	ASSTWEEcQP.LF.EETS.........................................EYRgigDEGVAREAFEEYVARLvDK.A...KE............
  784-  834 (83.19/35.49)	RERKREE.DK.VR.KEEK.........................................ERR...KEKERREKEKEKEKRL.KK.D...KDDSDSENLDMMME
  839-  883 (57.16/22.25)	TTK...E.DK..K.RDKK.........................................HRK...RHHHQQQQQDDNDDDA.TS.D...KD..EREDLDSSSK
  885-  933 (47.47/17.31)	SSSRRHG.KK.SR.KHAS.........................................AYS...PESDSRDSES.KHKKQ.KR.DsrkNGNGGGEELE....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.21|      13|      65|     405|     417|       6
---------------------------------------------------------------------------
  405-  417 (23.58/13.56)	AMRVIINDKRYGA
  473-  485 (23.63/13.60)	AMAMFEDDERYKA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17587 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ASMIPPNLHSSPMKMEDSSSHGVPKTLDGVSTHDTEEAKKGMAVAGKVNTT
2) NFSIQFRPVVPSQQGQAHAFMQSGSGSQQYRPQFSQPRPGQPPSSQAMPMSSYMQQQPNMPMSSSSSSSSSSYTFT
3) RERKREEDKVRKEEKERRKEKERREKEKEKEKRLKKDKDDSDSENLDMMMEITTTTTKEDKKRDKKHRKRHHHQQQQQDDNDDDATSDKDEREDLDSSSKKSSSRRHGKKSRKHASAYSPESDSRDSESKHKKQKRDSRKNGNGGGEELEDGELGAGEDGEIQ
4) VSSQFQMQTPVGGQPWPSSGNQGPLAVAPMPQTGHQPTNQQALNVLHSSSQEASSDWQEYTAGDGR
5) WTIPEELKLAREQAEKEASRSSQTEMVTNPNAPAISTPSALDQSSVNDISSTIPRVASSPAPHNVGSESSSVA
313
29
784
112
231
363
104
946
177
303










Molecular Recognition Features






MoRF SequenceStartStop




1) FSIQFR
2) GKKYY
3) GRRYYYN
4) KHRKRHHHQQ
5) KKSRKHASAYS
6) SKHKKQKRDSRK
30
217
176
849
892
912
35
221
182
858
902
923