<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17580

Description Uncharacterized protein
SequenceMSNRGNSSGSGSNSNISSSNRPEWLQQYDLIGKIGEGTYGLVFLAKIKSNRSKSIAIKKFKQSKDGDGVSPTAIREIMLLREITHDNVVKLVNVHINHIDMSLYLAFDYAEHDLYEIIRHHRDKVSQAINPYTVKSILWQLLNGLNYLHSNWIMHRDLKPSNILVMGDGEEQGVVKIADFGLARIYQAPLKPLFDNGVVVTIWYRSPELLLGGKHYTSAVDMWAVGCIFAELLTLKPLFQGQEVKATPNPFQKNGQHLPIFHIGKQISNTSKDTNIINHLTPIIYSPYSDSPGLYSVVHLSPKNPAYDLLSKMLEYDPRKRITAAQALEHEYFRMEPLPGRNALVPPQPGEKIVNYPTRPVDTNTDFEGTTSLQPTQQASGNVVSGGQHVMPTRNVPRPMHMAGMQRMQQQQQNMAAYGLASQAAMGGGGGAMNPGNIPMQRGVAAQQQQQQQQQQGTGKALKLSRDFTFEHLKSEKCKNKICCF
Length485
PositionKinase
OrganismLactuca sativa (Garden lettuce)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Cichorioideae> Cichorieae> Lactucinae> Lactuca.
Aromaticity0.08
Grand average of hydropathy-0.438
Instability index45.57
Isoelectric point9.26
Molecular weight54101.22
Publications
PubMed=28401891

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IBA:GO_Central
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IBA:GO_Central

GO - Biological Process
protein phosphorylation	GO:0006468	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17580
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     155.42|      35|      39|     379|     414|       1
---------------------------------------------------------------------------
  350-  378 (27.75/12.84)	.......GEKIVnyPTRPVDTNTDFEGTTSLQPTQQ.
  380-  414 (66.59/38.46)	SGNVVSGGQHVM..PTRNVPRPMHMAGMQRMQQQQQN
  422-  456 (61.08/38.75)	SQAAMGGGGGAM..NPGNIPMQRGVAAQQQQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.31|      30|      44|     164|     195|       2
---------------------------------------------------------------------------
  164-  195 (48.19/42.32)	LVMGDGEEQGVVKIADFGLarIYQA..PLKPLFD
  209-  240 (50.12/36.79)	LLLGGKHYTSAVDMWAVGC..IFAEllTLKPLFQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17580 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MEPLPGRNALVPPQPGEKIVNYPTRPVDTNTDFEGTTSLQPTQQASGNVVSGGQHVMPTRNVPRPMHMAGMQRMQQQQQNMAAYGLASQAAMGGGGGAMNPGNIPMQRGVAAQQQQQQQQQQGTGKALKLSRDFTF
335
470










Molecular Recognition Features






MoRF SequenceStartStop




1) KSIAIKKFK
53
61