Description | Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MADGQQRALTTAFAPPPPLWKHFTPDNLKKLEQIKKEASKNEDGKPQKKKWTAAELRSLDLPPELRLLVPPDIPTSGQYSVFGEVQNLSTALPELKDQGITQLYPSPGGEADREPSSEPARPLNHAYYLLKISKSLLLNFLEFVGLLSITPEQYESKVEDLRNLFVNAHHLLNLYRPHQARESLITMMEEQLSRTREEIQEMDKLKAEVTSALDRLKSQGIDVDATIGEEAKKATALAEPAQDNSKLIWDLLDDVN |
Length | 256 |
Position | Middle |
Organism | Aspergillus taichungensis |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus. |
Aromaticity | 0.06 |
Grand average of hydropathy | -0.590 |
Instability index | 37.20 |
Isoelectric point | 5.20 |
Molecular weight | 28816.37 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364060 ECO:0000256 ARBA:ARBA00003669 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP17568 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 78.40| 22| 45| 5| 26| 1 --------------------------------------------------------------------------- 5- 26 (43.69/22.23) QQRALTTA....FAPPPPLWKHFTPD 47- 72 (34.72/16.47) QKKKWTAAelrsLDLPPELRLLVPPD --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 84.55| 26| 118| 87| 113| 3 --------------------------------------------------------------------------- 87- 113 (42.11/28.38) NLSTALPELKDQGItQLYPSPGGEADR 208- 233 (42.44/24.29) EVTSALDRLKSQGI.DVDATIGEEAKK --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) KLIWDLLDDV 2) KPQKKKWTAAELRSLDLPPELRL 3) PLWKHFTPDNLKKLEQIKKEASKNE | 246 45 18 | 255 67 42 |
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