<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17567

Description Mediator of RNA polymerase II transcription subunit 16
SequenceMPLMMEDDGINMEDLFGQTGSFDMPPPSHPPNKALSHRLDEMRLSGCCQKIAWSRQGCVAYVSADATKVNLRYLHCQPADGKWDLSDDNPSTLPMETLPGHVVVHLSWNELGSDLAVIESSGRVSIFSIGIALNSVNAYRPAVDPDDDSAQVVGMMWLNSQRSVHAFNQAAKVQGRWAYSPFRRRPIGPFSPVHKSALVCVTKSGVIKFLYQSPDNRWGEISAELKNTSYSDRLLTHAALSSTQGGVLLVTHSVCQKICFYRVHINWTPPQYDSAQLKQVPVQFPAPTFRFSHVKVETPGGVPGPLHGEHDRSDHLCPIPSALYCLTRLDIILAAQDNAAGSTTNPWIVAIYSIPPHAASGLPQQSRPSTVIVRWQLDSAPHGLHPKFDEVASKKGPVQNKPKAVLRRLEDIQTDRYPISVDPTEYGNVVTVTFDDGSVAFYDPKTMSPFSGVDDANTVTSLAQAGFHYPLDPASGLHIDFSPSGCLAATLNGDGQVQLRGMEHSYGVENEGYDENKFSAAVAALTLAFSRGCGSEVNTDDIIMLARRQLSPDAQVSLVTEVYRALPINCDYTQEHEKQEKLMSNTYIPRCLSLQAALGFKDQFTSRSLASAIPWAILQIRHAAILYPFLFQYSKGVQGEPHDPDVLRTVLGNTKWALDFSHYLLNELFELADELESVASDPETLSQKLKSTASLPLIILLSSMSRAYLRIICRGLRGIYTGYANAAFTGDSRIYYTEIRQTLDASPVRVDVYEKFVAGIDSAVRHAYHGAGFGDAERPGPEKELLVNARIPPVLVTAVGTIFRQTLGVIKPEVDRLAIYMADYSWLGVGGDRRADVWRREREIDIVRKMPLRVTSAAAAAAAAASQVNNNGGVNQQQNQQQQQQPPRRRRCVRCCGLSDGSNPLRTGPIGYRLIHRLGYVRQCVCGGLWALEVEPVSLSG
Length941
PositionTail
OrganismAspergillus taichungensis
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus.
Aromaticity0.08
Grand average of hydropathy-0.228
Instability index44.92
Isoelectric point6.54
Molecular weight103520.23
Publications









Function






Annotated function

Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors. 


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17567
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     117.13|      43|      56|     445|     499|       1
---------------------------------------------------------------------------
  445-  499 (59.54/61.70)	KTMSPFSGVD....DANTVtSLAQAgfhypldpasGLHIDFSpSGC...........LA.ATLNGDGQVQL
  500-  558 (57.59/31.78)	RGMEHSYGVEnegyDENKF.SAAVA..........ALTLAFS.RGCgsevntddiimLArRQLSPDAQVSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.90|      26|      59|      84|     110|       4
---------------------------------------------------------------------------
   84-  110 (43.92/34.09)	DLSDDNPSTLPMETLPGHVVVHlSWNE
  144-  169 (47.98/32.53)	DPDDDSAQVVGMMWLNSQRSVH.AFNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.85|      30|      38|     615|     651|       7
---------------------------------------------------------------------------
  615-  647 (47.89/47.92)	WAiLQIRHaaILYPFLFQYSKGVQGEPHDPDVL
  656-  685 (51.96/30.06)	WA.LDFSH..YLLNELFELADELESVASDPETL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.13|      23|      38|     376|     398|       8
---------------------------------------------------------------------------
  376-  398 (41.41/23.86)	QLDSAPHGLHP.KFDEVAS...KKGPV
  413-  439 (31.72/16.67)	QTDRYPISVDPtEYGNVVTvtfDDGSV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17567 with Med16 domain of Kingdom Fungi
Unable to open file!