Description | Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MATGQDASMEEILWRSPPHVQMMGGYLHSNNILFYFAESPFFDATSNNASLAIQANYNEAFRHFVETREAFEARLKTMQGLEFIVAYDPLQAAAQSDTRFAHEPSNIWVIRKQTRQKRAGQEDEVAVLSTYFVVGDCIYMAPSVASVVGNRILSAVTSLSSLLKTASSLPTFTASHGYTYMPSAPKQLDAGQAGAQSQQSKENTPMPDADATAKGPLLGSQMANTGSVFQDTRTLAESFNLLSRYGDEFMDESPLVGEPGSFILSRSGDAERGPGAKQLAPPGVIPRVGTPQLKGETPGRTATPAASDEATLRKGKSKAGS |
Length | 321 |
Position | Head |
Organism | Aspergillus taichungensis |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus. |
Aromaticity | 0.08 |
Grand average of hydropathy | -0.351 |
Instability index | 49.71 |
Isoelectric point | 5.62 |
Molecular weight | 34512.24 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 PIRNR:PIRNR013286 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP17562 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 61.85| 19| 20| 229| 248| 1 --------------------------------------------------------------------------- 228- 247 (30.39/22.34) VFQDTRTL...AESFnLLSRYGD 248- 269 (31.46/18.26) EFMDESPLvgePGSF.ILSRSGD --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 52.78| 16| 22| 179| 198| 2 --------------------------------------------------------------------------- 179- 198 (25.49/20.61) TYMPSApkqlDAGQAGA..QSQ 204- 221 (27.29/12.79) TPMPDA....DATAKGPllGSQ --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 40.39| 11| 23| 272| 282| 3 --------------------------------------------------------------------------- 272- 282 (20.45/10.34) RGPGAKQLAPP 294- 304 (19.94/ 9.91) KGETPGRTATP --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) GRTATPAASDEATLRKGKSKAGS 2) QLAPPGVIPRVGTPQLKGET | 299 278 | 321 297 |
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