<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17558

Description Helix-loop-helix DNA-binding domain-domain-containing protein
SequenceMDQEQQGLSLQDISGPGDDDFSNFFAYGGHFAELDSHGSSDHQQPPPRSLSVSMPASTAPPTQDQWLQMDTTAFDSVMGDLPVDLAPHAHQSPSNGPAPASYAHAPMAPAFYSQKPSLPQVFHQQLTPDVQPQLHPSSQPSSQPYIPLGQTVIPPTPNSIELQGNAATYPRRIDDNHDLYDQYSRVDEQVLYTPLVSPAMTPLEAQLRLPEYTVPGEYFTPLTSPALEAQNANSNPYPFNPGPVSEMGFVPSPADSAMPGSSTPSSPAIIRHNHRPRPSTTTNKGFSTRAKKQQSPSVRPRTRKTSLLNINPDEILNGLNQDPSKSRPVGTSSLRYGSTESSGQDSVSPESLSEPLMPPPALPPARRSPAIAPQMSQSQNNEPATPAMLMRLQRQQQQQQQQQQQQQQQQQQQQQQSPATNIPAPPVSSGPYDDIMEDITLPEAANPTSYLARPEVPRIDTAVRTIAPSPASGVKSTPNLEPKSAPDRPLGSVAPSPRSIAMPSPSGPVGKKSDTPKLGPMARKRQSLSSSQPSPNLRPKISPSIKPMVRGDGVSSESSALYLASKSNYQHILDGTLLPGVSYPETLAENLSSKRTNHKLAEQGRRNRINTALKEIETLIPSAFVQMKNAKEAAACNVKVSEKEKEKNSNAQISKASTVEMAIDYIKALQQELKETKGKLVTAESRLKESAGNAESHKEGVTSPESGQAKSNTEAENASPSSSA
Length724
PositionTail
OrganismAspergillus taichungensis
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus.
Aromaticity0.04
Grand average of hydropathy-0.780
Instability index79.15
Isoelectric point6.31
Molecular weight78032.81
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
DNA binding	GO:0003677	IEA:UniProtKB-KW
protein dimerization activity	GO:0046983	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17558
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     130.77|      24|      25|     447|     470|       1
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  359-  373 (27.41/ 7.09)	P......PALP...PARR......SPA.IAP
  447-  470 (37.81/12.77)	PTSYLARPEVPRIDTAVR......TIA.PSP
  482-  505 (39.75/13.82)	PKSAPDRP.LGSVAPSPR......SIAmPSP
  508-  535 (25.80/ 6.22)	PVG..KKSDTPKLGPMARkrqslsSSQ.PSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     444.90|     122|     179|      53|     175|       2
---------------------------------------------------------------------------
   53-  169 (202.74/81.25)	......S.MP......................ASTAPPTQDQWLQMDTTAFDSVMGDLPVDLAPHAHQSP.SNGPAPASYAHAPMAP.AFYSQKPSL.PQVFHQQL...TPD.VQPQLH..PS.SQP...SSQP.Y.IPlGQTVIPPTPNSIELQ.GNAATY
  170-  237 (91.70/31.40)	PRRIDD..................................................................NHD..............LYDQYSRVdEQVLY......TPL.VSPAMT..PL.EAQ...LRLPeYtVP.GEYFTPLTSPALEAQnANSNPY
  251-  348 (111.47/39.82)	PSPADSA.MP......................GSST.PSSPAIIR...................HNHR......PRPSTTTNKGFSTrAKKQQSPSVrPRTRKTSLlniNPDeILNGLNqdPSkSRPvgtSSLR.Y.............GSTESS.GQDSVS
  349-  425 (38.99/ 8.76)	PESLSEPlMPppalpparrspaiapqmsqsqnNEPATPAMLMRLQRQQQQQQQQQQQQQQQQQQQQQQSPaTNIPAP.....................................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.02|      14|      26|     553|     566|       3
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  553-  566 (23.80/18.37)	GVS.SESSALYLASK
  580-  594 (20.22/14.18)	GVSyPETLAENLSSK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17558 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AELDSHGSSDHQQPPPRSLSVSMPASTAPPTQDQWLQMDTTAF
2) LPQVFHQQLTPDVQPQLHPSSQPSSQPYIPLGQTVIPPTPNSIELQGNAATYPRRIDDNHDLYDQYSR
3) TKGKLVTAESRLKESAGNAESHKEGVTSPESGQAKSNTEAENASPSSSA
4) VMGDLPVDLAPHAHQSPSNGPAPASYAHAPMAP
5) VPGEYFTPLTSPALEAQNANSNPYPFNPGPVSEMGFVPSPADSAMPGSSTPSSPAIIRHNHRPRPSTTTNKGFSTRAKKQQSPSVRPRTRKTSLLNINPDEILNGLNQDPSKSRPVGTSSLRYGSTESSGQDSVSPESLSEPLMPPPALPPARRSPAIAPQMSQSQNNEPATPAMLMRLQRQQQQQQQQQQQQQQQQQQQQQQSPATNIPAPPVSSGPYDDIMEDITLPEAANPTSYLARPEVPRIDTAVRTIAPSPASGVKSTPNLEPKSAPDRPLGSVAPSPRSIAMPSPSGPVGKKSDTPKLGPMARKRQSLSSSQPSPNLRPKISPSIKPMVRGDG
32
118
676
77
214
74
185
724
109
553










Molecular Recognition Features






MoRF SequenceStartStop




1) LRPKISPSIKPMV
2) MDQEQQGLSLQDISGPGDDDFSNFFAYGGHFAELD
3) PYDDIMEDITL
537
1
431
549
35
441