<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17525

Description mediator of RNA polymerase II transcription subunit 15a-like
SequenceMRQGLGVKPGVFQQHLSGGQRAAYSHQQLKSGGSFPISSPQLQVASPQILQHSSPQIDQQNVLSSLTKAGTPLQSASSPFVVPSPSTPLAPSPMPGDAEKPITGVSSHSNAGNIGHQQTSGVGAPVPSLAIGTPGISASPLLAEFTGQDGTLGNALMNVSGKSSITEQPLERLIKAVKSMSPKALSASVSDIGSVVSMIDRIASSAPGNGSRAAVGEDLVAMTKCRLQARNFITQDGTNGTRKMKRYTSAMPLSVVSSAGSMNDNFKQLMGSETSDLESTATSSVKRPRIEVNPALLEEIREINQGLFDTVVDISDEDVDPTATAAAADGGEGTIVKCSFIAVALSPNLKSQYTSAQMSPIQPLRLLVPSNYPNCSPILLDKFPVEVSKKYEDLSVKAKSRFSISLRTLSQPMSLGQIARTWDVCARAVISEHAQQSGGGTFSSKYGTWENCLSTA
Length456
PositionTail
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.04
Grand average of hydropathy-0.198
Instability index51.82
Isoelectric point8.50
Molecular weight47754.44
Publications
PubMed=27145194

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17525
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     275.21|      76|      84|     122|     201|       1
---------------------------------------------------------------------------
   36-  124 (77.19/43.19)	PIssPQ....LQVASPQIlqHSSP..QID.Q...Q.....NVL......SSLTKagTPLQSASSPFVVPSP..STPLApspmpgdaekpitgvsS.HSNA.GNIgHQQTSGVGA
  125-  204 (118.98/79.38)	PV..PS....LAIGTPGI..SASP..LLA.EFTGQDGTLGNALMnvsgKSSITE..QPLERLIKAVKSMSP..KALSA................S.VSDI.GSV.VSMIDRIAS
  205-  287 (79.04/44.41)	SA..PGngsrAAVGEDLV..AMTKcrLQArNFITQDGTNGTRKM....KRYTSA..MPL.SVVSSAGSMNDnfKQLMG................SeTSDLeSTA.TSSVKR...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.65|      15|     404|      21|      35|       2
---------------------------------------------------------------------------
   21-   35 (28.64/20.68)	RAAYS.HQQLKSGGSF
  427-  442 (24.01/15.99)	RAVISeHAQQSGGGTF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.90|      22|      48|     345|     366|       3
---------------------------------------------------------------------------
  345-  366 (38.32/23.89)	LSPNLKSQYTSAQMSPIQPLRL
  394-  415 (35.58/21.66)	LSVKAKSRFSISLRTLSQPMSL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17525 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LQSASSPFVVPSPSTPLAPSPMPGDAEKPITGVSSHSNAGNIGHQQTSGVGAPVPSL
2) PQLQVASPQILQHSSPQIDQQNVLSSLTKAG
3) RQGLGVKPGVFQQHLSGGQRAAYSHQQLKSGGSFPIS
73
40
2
129
70
38










Molecular Recognition Features






MoRF SequenceStartStop




NANANA