<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17505

Description mediator of RNA polymerase II transcription subunit 6-like
SequenceMATPPVASVPPANQGLEGGQPAPPAPPGTDMTGICFRDQLWLNTYPLDRNLVFDYFALSPFYDWTCNNEQLRMRSIHPLDLSHLSKMAGIEYMLYEVMEPHLFVIRKQKRDGPEKVTPMLTYYVLDGSIYQAPQLCNVFAARVGRALYYISKAFTTAASKLEKIGYVDAENDSAALESKVAKETIDFKEVKRVDHILASLQRKLPPAPPPPPFPEGYVPPHTADAEKGPEGPQSGEPQAPSVDPIIDQGPAKRMKI
Length256
PositionHead
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.09
Grand average of hydropathy-0.378
Instability index55.60
Isoelectric point5.77
Molecular weight28364.20
Publications
PubMed=27145194

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coactivator activity	GO:0003713	IBA:GO_Central

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17505
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.98|      14|      30|      35|      48|       1
---------------------------------------------------------------------------
   35-   48 (29.10/15.50)	CFRDQLWL.NTYPLD
   66-   80 (21.89/10.30)	CNNEQLRMrSIHPLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      29.93|       9|      24|     115|     124|       2
---------------------------------------------------------------------------
  115-  124 (13.17/10.84)	KVTPMLtYYV
  142-  150 (16.76/ 8.70)	RVGRAL.YYI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.13|      12|     199|       4|      15|       3
---------------------------------------------------------------------------
    4-   15 (24.63/ 7.83)	PPVASVPPANQG
  205-  216 (27.50/ 9.43)	PPAPPPPPFPEG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17505 with Med6 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ASLQRKLPPAPPPPPFPEGYVPPHTADAEKGPEGPQSGEPQAPSVDPIIDQGPAKRM
198
254










Molecular Recognition Features






MoRF SequenceStartStop




1) LASLQRK
2) VDPIIDQGPAKRMKI
197
242
203
256