<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17499

Description pre-mRNA-processing protein 40C isoform X1
SequenceMASPAWLTQEIQPSASQAPVPGTSAVVSSGGPSTPTAAAPAPGAVTPTSKGLLGTASGSTQGPNQARFSNAPGYAVAPPLFSYNVLSNASTPPGSSQQSSSNSVINSNPPASPLLVQLPVSGVSSSSSPSFSYNISQSSVAFPSNQQFQSSGNSLTAVAQEAGTLSSASTIPQPVSLPADNSTSSTIPVSSISSLNQVTSWVPSAPSFFMPPGMPGTPGTPGPPGIAAPAQISSNLTVLSVATDSSSSAVPRPTMPTAPVLSSSAVQTANYPYASFPAMAAPPQGMWLQPSQMGGLPRSPFQPYPAAFPGPFPLPARGMALPSVPLPDSQPPGVTPLGTAPTISVSSAASGHMLAGTLRMQPELPPPGIDNRKNVEEVGTQDGAAVKEQLDAWTAHKTEAGVVYYYNAVTGESTYDKPLGFKGEHDKVHVQPTPVSTTSILGTDWVLVTTSDGKKYYYNSKTKISSWQIPSEVTELKKKQDGEHSISLPHANLSTEKGSAPISLNAPAISTGGRDAMALKALAVPGSSSALDMIKKKLQDSGSPITSSPNPAPSGIAASELNGSRAVDTTVKGLQSEDSRDKLKDANGDGNMSDSSSDSEDADSGPTKEECIIQFKEMLKERGVAPFSKWEKELPKIVFDPRFKAIPSYSARRSLFEHYVKTRAEEERKEKRAAQKAAIEGFKQLLGEASEDIDHNTDYQTFRKKWGADPRFEVLDRKDREHLLNERVFPLKKAAEEKVQALRAAAATSFKSMLREKRDITANSRWSKVKDSLRNDSRYKSAKHEDREIFFNEYISELKAGEEQSEREAKAKREEQEKLKERERELRKRKEREEQEMERVRLKVRRKEAVASFQALLVEIIKDPQASWTESKPKLEKDPQGRATNTDLDPSDIEKLFREHIKMLNERCVQEFRYLLAEVLTAEAAAQETEEGKTVLNSWSTAKRLLKPDPRYNKMPRKEREVLWRRYADEILRRQKVALDQKEEKKHVESKGRNSADSGRFLSGSRRRTHDRR
Length1013
PositionUnknown
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.06
Grand average of hydropathy-0.654
Instability index58.80
Isoelectric point9.03
Molecular weight109946.92
Publications
PubMed=27145194

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
RNA polymerase binding	GO:0070063	IBA:GO_Central
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17499
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     449.28|      65|      65|     673|     737|       1
---------------------------------------------------------------------------
  553-  617 (32.95/14.23)	........PSGIAASElngsrAVD....TTVKG...LQSEDSRDklKDANGDgnmSDSSSDSEDADsgPTKEecI....IQF.K.......E.
  618-  654 (44.32/21.77)	MLKERgVAPFSKWEKE.....L......................................PKIVFD..PRFK..A....IPSySA.....RRS
  655-  722 (96.06/56.10)	LFEHY.V..KTRAEEErkekrAAQ...KAAIEGFKQLLGEASED..IDHNTD...YQTFRKKWGAD..PRFE..V....LDR.KD.....REH
  723-  789 (91.10/52.81)	LLNER.VFPLKKAAEE..kvqALR...AAAATSFKSMLRE.KRD..ITANSR...WSKVKDSLRND..SRYK..S....AKH.ED.....REI
  790-  834 (50.21/25.68)	FFNEY.ISEL.KAGEEqsereA.....KA.....KR...EEQEK..L.........KE.RER.........E..L....RKR.KE.....REE
  835-  900 (62.38/33.75)	QEMER.V.RLK.............vrrKEAVASFQALLVEIIK....DPQAS...WTESKPKLEKD..PQGR..AtntdLDP.SDieklfREH
  903-  962 (72.26/40.31)	MLNER.CV.......QefrylLAE...VLTAEAAAQ...ETEEG..KTVLNS...WSTAKRLLKPD..PRYN..K....MPR.KE.....REV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      96.17|      26|      27|     287|     313|       2
---------------------------------------------------------------------------
   47-   68 (28.06/ 8.65)	PTSKG......LL.....GTASGSTQ...GPNQARF
  277-  308 (39.19/18.90)	PA.MAappqgmWLqPSQMGGLPRSPF...QPYPAAF
  309-  335 (28.91/ 9.15)	PGPFP........lPARGMALPSVPLpdsQP.PGVT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     232.06|      45|      49|      79|     124|       3
---------------------------------------------------------------------------
   18-   90 (42.38/15.53)	APvPG..............TS...........AV.VSSGGPSTP.TAAAPAPGAVtptskgllgtasgstqgpnqarfsnapgyavapPLFSYNV.LSNAS
   91-  140 (66.36/31.76)	TP.PG..............SSQ.QSSSN....SV.INSNPPASPlLVQLPVSGVS.............................ssssPSFSYNI.SQSSV
  141-  169 (30.92/ 9.35)	AF.PS..............NQQfQSSGN....SL.TAVAQEAG....................................................tLSSAS
  170-  207 (45.37/17.14)	TI.PQ..............PVS.LPADN....ST.SST..........IPVSSIS..............................slnQVTSW.V.PSAPS
  210-  270 (47.02/18.03)	MP.PGmpgtpgtpgppgiaAPA.QISSNltvlSVaTDSSSSAVP....RPTMPTA.................................PVLSSSA.VQTAN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     111.51|      24|      50|     393|     416|       5
---------------------------------------------------------------------------
  393-  416 (43.38/29.27)	WTAHKTEAGVVYYY......NAVTGESTYD
  418-  444 (26.37/14.99)	PLGFKGEHDKVHVQptpvstTSILGT...D
  445-  468 (41.77/27.92)	WVLVTTSDGKKYYY......NSKTKISSWQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17499 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ALDQKEEKKHVESKGRNSADSGRFLSGSRRRTHDRR
2) DMIKKKLQDSGSPITSSPNPAPSGIAASELNGSRAVDTTVKGLQSEDSRDKLKDANGDGNMSDSSSDSEDADSGPTKEECI
3) GEEQSEREAKAKREEQEKLKERERELRKRKEREE
4) IPSEVTELKKKQDGEHSISLPHANLSTEKGSAPISLNAPAIS
5) LAGTLRMQPELPPPGIDNRKNVEEVGTQDGAAVKEQLDA
6) MASPAWLTQEIQPSASQAPVPGTSAVVSSGGPSTPTAAAPAPGAVTPTSKGLLGTASGSTQGPNQARFSNA
7) SSGNSLTAVAQEAGTLSSASTIPQPVSLPADNST
978
532
801
469
354
1
150
1013
612
834
510
392
71
183










Molecular Recognition Features






MoRF SequenceStartStop




1) FFNEYI
2) MASPAWLTQEI
3) WRRYA
790
1
964
795
11
968