<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17497

Description mediator of RNA polymerase II transcription subunit 33A-like isoform X1
SequenceMAVSVHTGIWDSVRELTRVAQRKGSDPLHWALQVSSNLNSAGVALPSAELADVLVSYICWDNNLPILWKFLEKALVLKIVPPMFVLALLSTRVIPHRKSWPVAYRLYLELLKRHAFALKFQINDLNYQKVMESIDDVLLLSQRFGMTPSEPGILVVQFIFSIVWQLLDATLDDEGLLELTSDEKSIWATKSQDMQIDYHDIYDEKRAELQERLQNENTVMSVDLIGQFLQNKVISRIIFLARRNMPTHWVHFIQRLRLLETNSSALRNSNALTPEALHQLTSDAPTVLSREYKTTSLQKFHAVMAFGSLSSSAGPCQGANRSALWLPLDLLLEDVMDGCLVNATSAIEIISGLIKTLQAINGTSWHDTFLALWIASLRLVQRERDPIEGPVPRLDTRLCILLSITTLVVADLIEEESAPVDETECGSTNHWKDKKVTGKCHNDLVSSLQILRDYQGLLTPPQSVVSAANQAAAKAMLFASGINVGSAYFECIGLKDMPINCSGNMRHLIVEACIARNLLDTSAYLWPGYVNGQINQIPHSVPAQAPSWSSFMKGAPLTPLLINALVSTPASSLAELEKIFDIAVKGTDDEKISAATILCGASLIRGWNIQEHTIHFIARLLSPPAPPKYCGNGSHLIGYAPMLNVLIVGIASIDCIQIFSLHGLVPQLACSLMPICEVFGSCVPDVPWVLTNGEEVSAHAVFSNAFILLLKLWRFNHPPLEHGVGETPTVGSQLTPEYLLLLRNSHLVSSGNVNKSRNRRRLSAVASLLSPQPVFVDSFPKLKAWHRQHQACIASTLSGLVHGTPVHKIVDGLLNMMFKKINRGGQSLTVTSGSSSSSGPGNEDTSLRPKLPSWDILEAVPFVVDAALTACAHGKLSPRELATGLKDLADFLPASLATIVSYFSAEVTRGVWKPAFMNGTDWPSPAANLFNVEEQIKKILATTGVDIPSLSAGGSSPSTLPLPLAAFVSLTITYKIDRASERFLNLAGPALESLAAGCPWPCMPIVASLWTQKAKRWSDFLVFSASQTVFLHNSDAVVQLLKSCFAATLGLNDIPISSSGGVGALLGHGFGSHFCGGISPVAPGILYLRVYRSIRDIVFITEEVVSLLMHSVRDIVSSGLPRERLENLRTSKIGMRYRQVSLAASMTRVKVAAALGASLVWLSGGLSLVQSLIKETLPSWFISVHRSELEEGSEGMVAMLAGYALAYFAVLCGAFAWGVDSTSSASKRRPKILGTHLEFLASAVDGKISLGCDWATWRAYVSGFVTLMVGCTPNWALEVDADVLKRLSNGLRLWNEEELALALLGIGGVGTMGAAAELIIENDM
Length1324
PositionTail
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.07
Grand average of hydropathy0.205
Instability index39.00
Isoelectric point6.44
Molecular weight144172.12
Publications
PubMed=27145194

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17497
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     299.13|      74|     303|     532|     607|       1
---------------------------------------------------------------------------
  533-  607 (119.26/87.99)	QINQIPHSVPAQ.APSWSSFMK.GAPLTPLLINALVS.TPASSLAE.LEKIFDIAVKGTDDEKISAATILcGASLIRGW
  935-  998 (76.83/45.10)	QIKKILATTGVD.IPSLSAGGS.SPSTLPLPLAAFVSlTITYKIDRaSERFLNLA..GPALESLAAGC...........
 1001- 1070 (103.04/65.11)	PCMPIVASLWTQkAKRWSDFLVfSASQTVFLHN.......SDAVVQ.LLKSCFAATLGLNDIPISSSGGV.GALLGHGF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     114.40|      34|     160|     457|     492|       2
---------------------------------------------------------------------------
  457-  492 (54.37/40.28)	LLTPPQSVVSAANqaAAKAMLFASGIN...VGSAYFECI
  620-  656 (60.03/38.39)	LLSPPAPPKYCGN..GSHLIGYAPMLNvliVGIASIDCI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.95|      17|     160|     161|     177|       3
---------------------------------------------------------------------------
  161-  177 (30.51/17.37)	SIVWQLLDATLDD..EGLL
  322-  340 (27.43/14.85)	SALWLPLDLLLEDvmDGCL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.50|      12|     365|     244|     255|       4
---------------------------------------------------------------------------
  244-  255 (26.52/19.64)	NMPTHWVHFIQR
  608-  619 (22.98/15.96)	NIQEHTIHFIAR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.57|      20|     365|     734|     823|       5
---------------------------------------------------------------------------
  697-  717 (32.58/64.46)	SAHAVFSNAFIlLLKLWRFNH
  770-  789 (39.99/64.69)	SPQPVFVDSFP.KLKAWHRQH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.27|      10|     930|     145|     154|       8
---------------------------------------------------------------------------
  145-  154 (20.70/11.22)	GMTPSEPGIL
 1077- 1086 (19.57/10.20)	GISPVAPGIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.34|      13|    1243|      24|      37|      12
---------------------------------------------------------------------------
   24-   37 (21.68/14.32)	GSDPlHWALQVSSN
 1270- 1282 (26.66/13.59)	GCTP.NWALEVDAD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.70|      27|     728|     369|     398|      14
---------------------------------------------------------------------------
  369-  398 (39.01/35.69)	FLALWIASLrLVQRERDPIEGPVPRldTRL
 1099- 1125 (45.68/29.23)	FITEEVVSL.LMHSVRDIVSSGLPR..ERL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17497 with Med33 domain of Kingdom Viridiplantae
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