<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17489

Description mediator of RNA polymerase II transcription subunit 8 isoform X4
SequenceMEGVVVQNQSQQQQQQQQQQQQQQQPERLNQAVQQQLNLEAVKTRAISLFKAISRILEDFDAYARTNTTPKWQDILGQYSMVNLELFNIVDEIKKVSKAFVVNPKNVNAENSTILPVMLSSKLLPEMEMDDNSKREQLLHGMQNLPISSQIEKLKARIDMIGAACESAEKVLADTRKAYCFGTRQGPSIAPTLDKGQAAKIHEQENLLRAAVHLGEGLRMSGEQRQITPALPLHLVDVVTGGDGMQSFADTSGMYLKNNPMSSSNISGQGTLLSASASQLIGRSAASPGATSATSFDNTAASPLQYANSPRSGTNMMNTPSPQPQTPQQQQQQQQQQRQKLMQIPQHQPQILAQQQFRQSAMQGLAQNQLPQLHDLQGQAQQKFQSLHGQNQMQFSQAMGHQQFQRQLPSGHVQHGIGQSQLNQGNQMNRHLSQFSGNANSALFNAAQATSNTQMIPNISATMSSQSLIPRMQCLIWEQPILVV
Length484
PositionHead
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.04
Grand average of hydropathy-0.599
Instability index55.79
Isoelectric point8.90
Molecular weight53503.72
Publications
PubMed=27145194

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17489
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     389.50|      81|     311|       1|      81|       1
---------------------------------------------------------------------------
    1-   81 (136.09/43.84)	MEGVVVQNQSQQQQQQQQQQQQQQ.......QPE.RL.NQAV.QQQLNLEAVKTRAISLF..KA....ISRILEDF.DAYA.RTNTTPKWQDIL..GQYSM
  117-  197 (70.81/19.87)	...VMLSSKLLPEMEMDDNSKREQ.......LLH.GMqNLPI.SSQ..IEKLKAR.IDMI..GAacesAEKVLADTrKAYCfGTRQGPSIAPTLdkGQ...
  317-  393 (109.93/34.24)	MNTPSPQPQTPQQQQQQQQQQRQKlmqipqhQPQ.IL.A....QQQFRQSAMQGLAQNQL..PQ........LHDL.QGQA.Q....QKFQSLH..GQNQM
  402-  468 (72.68/20.55)	..................QQFQRQ.......LPSgHV.QHGIgQSQLNQGNQMNRHLSQFsgNA....NSALFNAA.QATS.NTQMIPNISATM..SSQSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      32.79|      10|      24|     277|     288|       2
---------------------------------------------------------------------------
  277-  288 (13.05/10.57)	ASQLigRSAASP
  301-  310 (19.74/ 9.08)	ASPL..QYANSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.42|      12|      23|     203|     214|       3
---------------------------------------------------------------------------
  203-  214 (19.79/12.75)	EQENLLRA.AVHL
  223-  235 (17.64/10.58)	EQRQITPAlPLHL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17489 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ASQLIGRSAASPGATSATSFDNTAASPLQYANSPRSGTNMMNTPSPQPQTPQQQQQQQQQQRQKLMQIPQHQPQILAQQQFRQSAMQGLAQNQLPQLHDLQGQAQQKFQSLHGQNQMQFSQAMGHQQFQRQLPSGHVQHGIGQSQLNQGNQMNRHLSQFSG
277
437










Molecular Recognition Features






MoRF SequenceStartStop




NANANA