<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17486

Description mediator of RNA polymerase II transcription subunit 8 isoform X1
SequenceMEGVVVQNQSQQQQQQQQQQQQQQQPERLNQAVQQQLNLEAVKTRAISLFKAISRILEDFDAYARTNTTPKWQDILGQYSMVNLELFNIVDEIKKVSKAFVVNPKNVNAENSTILPVMLSSKLLPEMEMDDNSKREQLLHGMQNLPISSQIEKLKARIDMIGAACESAEKVLADTRKAYCFGTRQGPSIAPTLDKGQAAKIHEQENLLRAAVHLGEGLRMSGEQRQITPALPLHLVDVVTGGDGMQSFADTSGMYLKNNPMSSSNISGQGTLLSASASQLIGRSAASPGATSATSFDNTAASPLQYANSPRSGTNMMNTPSPQPQTPQQQQQQQQQQRQKLMQIPQHQPQILAQQQFRQSAMQGLAQNQLPQLHDLQGQAQQKFQSLHGQNQMQFSQAMGHQQFQRQLPSGHVQHGIGQSQLNQGNQMNRHLSQFSGNANSALFNAAQATSNTQMIPNISATMSSQSLIPRMQFGLSGSNPQRSHASQILSDQMFNMGAANPSGMMPIQQQQQQQQQQHGSQTAFGNMQPNAQNLQPGMVALQNTQQNLSNFSQQRQQNPQ
Length561
PositionHead
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.04
Grand average of hydropathy-0.722
Instability index57.03
Isoelectric point9.28
Molecular weight61916.63
Publications
PubMed=27145194

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17486
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.86|      19|      23|     283|     305|       2
---------------------------------------------------------------------------
  285-  305 (28.92/22.08)	AASPgaTSATSFDNTAA....SPLQ
  307-  329 (31.94/12.36)	ANSP..RSGTNMMNTPSpqpqTPQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     319.51|      91|     180|     191|     281|       4
---------------------------------------------------------------------------
  153-  264 (130.66/45.77)	KLKARIDMIGA.aceSAEK.............VLadtrkaycfgtrqgpsiaPTLD..KG....QAAK....IHEQENLLRAAVHLGEGLRMSGE...QRQITPALP.LHLVDVVTGGDGMQSFADT..SGMY.LKNNPMSSS
  371-  435 (76.59/23.84)	....................................................PQLHdlQG....QAQQkfqsLHGQNQM.....QFSQAMGHQQF...QRQ....LPsGH....VQHGIGQSQLNQG..NQM....NRHLSQF
  436-  550 (112.27/38.31)	SGNANSALFNAaqatSNTQmipnisatmssqsLI..................PRMQ..FGlsgsNPQR....SHASQILSDQMFNMGAA.NPSGMmpiQQQQQQQQQ.QHGSQTAFG..NMQPNAQNlqPGMVaLQNTQQNLS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17486 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ASQLIGRSAASPGATSATSFDNTAASPLQYANSPRSGTNMMNTPSPQPQTPQQQQQQQQQQRQKLMQIPQHQPQILAQQQFRQSAMQGLAQNQLPQLHDLQGQAQQKFQSLHGQNQMQFSQAMGHQQFQRQLPSGHVQHGIGQSQLNQGNQMNRHLSQFSGNANSALFNAAQATSNTQMIPNISATMS
2) QSLIPRMQFGLSGSNPQRSHASQILSDQMFNMGAANPSGMMPIQQQQQQQQQQHGSQTAFGNMQPNAQNLQPGMVALQNTQQNLSNFSQQRQQNPQ
277
466
464
561










Molecular Recognition Features






MoRF SequenceStartStop




NANANA