<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17485

Description mediator of RNA polymerase II transcription subunit 23
SequenceMDQTQHQRPVPASAPAPASRAYQFHPARAAIVDLFDLYLGRSSRQKPEDSSREPPNKTQKRVHALNRELPPRNEQFLIDFEQLQSQFAEQDQLRSVTESIFISLVVKCSGHAPRAEFLLFALRNLCTIGFINWDTLLPSLLSSVSSAEMTVGSQAMPAVSSTSLPQTGMLPPSSSIPNPSTFQSSNPASPLTTVHGIGSPAQCALEPPPCATLSPVKSSDILCNGQQPTARINSSIRDNAISSLRQLCCKIILTGLEFDLKPVTHAEIFYHMLNWLVNWDQRQQGIDEFDGAKSWRPHKALIEWLHSCLDVIWLLVEEDKCRVPYYELLRSGLQFIENIPDDEALFTLILEIHRRRDMMAMHMQMLDQHLHCPTFGTHRVLSQTTPNISGEATANARYSPITYPSVLGEPLHGEDLAMSIQKGSLDWERALRCIRHALRSTPSPDWWKRVLLVAPSYRSPQAPTPGAVFTSEMICEATIDRIVELLKFTNSEINCWQEWLVFSDIFFFLMKSGCIDFVDFVDKLVSRVMEGDQHILRTNHVTWLLVQLLRVELVMNALNSDARKVETTRKVLSFHREDRSSDPNNPQSILLDFISSCQNLRIWSLNTSTREYLNNEQLQKGKQIDEWWRQVSKGDRKMDYMNMDDRSIGMFWVVSYTMAQPACETVMNWLSSAGVTEFLPGPNLQSNERLMVMREVSPLPMSLLCGFSMNLCSKLAYQMEETLFSGQGVPNIAMVETYTRLLLIAPHSLFRPHFSNLAQRNPSLLSKPGVTLLVLEILNYRLLPLYRYEGKSKALMYDVTKIISTLKGKRGDHRVFRLAENLCMNLIFSLRDFFSVKREGKGPTEFTETLNRITIITLAITIKTRGIADADHLLYLQTMVEQIMATSLHTWSEKTVRYFPSVLREALMGRMDKRSLEIQAWQKAETTVINQCTQLLSPSADPSYVTTYISHSFPMHRRYLCAGAWILMHGHPENINSVNLARVLREFSPEDVTENIYTMVDVLVHHIQMELQHGHPLQDLLLKVCANLAFFVWTHELLPLDILLLALIDRDDDPHALRIVINLLERQELLQRVKLYCMNRGTPEHWLYTGMFKRVELQKALGNHLSWKDRYPTFFDDVAARLLPVVPLIVYRLIENDATDPAERILAMYSSFLAFHPLRFTFVRDILAYFYGHLPGKLIVGILNVLDLSKIPYSESFPQLISSSNPVMCPPMDYFTTLLLGLVNNVIPPLHNNSRFGSMCDPSGRTPYNKTAATSQSGLANASEGQKSFYQIQDPGTYTQLVLETAVIELLSLPVSASQIVSSLVQIVVNIQPTLIQSSNGLHGAPNGVGQASVLPTSPSGGSTDSLSAGRSTPLVSGINTSNIVSRSGYTCQQLSCLLIQACGLLLAQLPPEFHLQLYAEASRIIKESWWLTDGKRSLGELDSAVGYALLDPTWAAQDNTSTAIGNTVALLHSFFTNLPQEWLEGTHVIIKHLRPVTSVAMLRIAFRIMGPLLPRLANAHSLFNKVQ
Length1508
PositionTail
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.08
Grand average of hydropathy-0.083
Instability index49.80
Isoelectric point6.60
Molecular weight170029.99
Publications
PubMed=27145194

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central

GO - Biological Function
GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17485
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     206.55|      69|     124|     675|     750|       1
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  675-  750 (107.83/85.01)	VTEF...LPGPnlQSNERlmVMREVSPLPMSLLCG....FSMNLCSKLAYQMEETLfsgQGVPNIAM.VETYTRLLLIAPHSLF
  799-  875 (98.71/59.83)	VTKIistLKGK..RGDHR..VFRLAENLCMNLIFSlrdfFSVKREGKGPTEFTETL...NRITIITLaITIKTRGIADADHLLY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     122.26|      39|      45|     911|     955|       2
---------------------------------------------------------------------------
  913-  955 (59.78/57.07)	KRSLEIQAW..QKAETTVINQC..TQLLSPSAdPSYVTTYIshsFPM
  957-  999 (62.47/38.03)	RRYLCAGAWilMHGHPENINSVnlARVLREFS.PEDVTENI...YTM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.05|      30|      45|      71|     100|       3
---------------------------------------------------------------------------
   71-  100 (51.50/33.27)	PRNEQFLIDFEQLQS.QFAEQDQ.LRSVTESI
  113-  144 (44.55/27.73)	PRAEFLLFALRNLCTiGFINWDTlLPSLLSSV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     347.39|     112|     963|     373|     500|       5
---------------------------------------------------------------------------
  373-  500 (173.07/136.00)	PTFGTHRVLS..QTTPNISGEATANAryspITYPSVLGEPL.hgedlAMSIQKGSLDWERALRCIRHALRsTPSPDWW....KRVLLVAPSYRSPQAPTPgaVFTSEMICEATIDRIVELLK..FTNseINcwQEWL
 1339- 1464 (174.32/97.54)	PSGGSTDSLSagRSTPLVSGINTSNI....VSRSGYTCQQLsclliqACGLLLAQLPPEFHLQLYAEASR.IIKESWWltdgKRSLGELDSAVGYALLDP..TWAAQDNTSTAIGNTVALLHsfFTN..LP..QEWL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     260.37|      85|     470|     578|     672|       6
---------------------------------------------------------------------------
  578-  672 (137.36/105.58)	DRSSDPNNPQSI..LLDFISSCQNLRIWSLNTSTRE.YLNNE.....QLQK..GKQIDewWRqvskgDRKMDYmnMDD...RSIGMFWVVSYTMAQ.....PAcETVMNWLSS
 1049- 1151 (123.02/70.31)	DRDDDPHALRIVinLLERQELLQRVKLYCMNRGTPEhWLYTGmfkrvELQKalGNHLS..WK.....DRYPTF..FDDvaaRLLPVVPLIVYRLIEndatdPA.ERILAMYSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.41|      16|      19|     165|     183|       7
---------------------------------------------------------------------------
  165-  183 (21.96/18.06)	PQTGmLPPSSSIPNPStfQ
  187-  202 (26.45/10.66)	PASP.LTTVHGIGSPA..Q
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17485 with Med23 domain of Kingdom Viridiplantae
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